The nisin–lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics STD Hsu, E Breukink, E Tischenko, MAG Lutters, B De Kruijff, R Kaptein, ... Nature structural & molecular biology 11 (10), 963-967, 2004 | 670 | 2004 |
The α‐to‐β conformational transition of Alzheimer's Aβ‐(1–42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of β … S Tomaselli, V Esposito, P Vangone, NAJ van Nuland, AMJJ Bonvin, ... ChemBioChem 7 (2), 257-267, 2006 | 512 | 2006 |
Following protein folding in real time using NMR spectroscopy J Balbach, V Forge, NAJ van Nuland, SL Winder, PJ Hore, CM Dobson Nature structural biology 2 (10), 865-870, 1995 | 308 | 1995 |
Allostery and intrinsic disorder mediate transcription regulation by conditional cooperativity A Garcia-Pino, S Balasubramanian, L Wyns, E Gazit, H De Greve, ... Cell 142 (1), 101-111, 2010 | 281 | 2010 |
The Fic protein Doc uses an inverted substrate to phosphorylate and inactivate EF-Tu D Castro-Roa, A Garcia-Pino, S De Gieter, NAJ Van Nuland, R Loris, ... Nature chemical biology 9 (12), 811-817, 2013 | 202 | 2013 |
Protein folding monitored at individual residues during a two-dimensional NMR experiment J Balbach, V Forge, WS Lau, NAJ van Nuland, K Brew, CM Dobson Science 274 (5290), 1161-1163, 1996 | 176 | 1996 |
NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles: Conformational changes are a key to antimicrobial activity STD Hsu, E Breukink, G Bierbaum, HG Sahl, B De Kruijff, R Kaptein, ... Journal of Biological Chemistry 278 (15), 13110-13117, 2003 | 171 | 2003 |
Slow folding of muscle acylphosphatase in the absence of intermediates NAJ van Nuland, F Chiti, G Raugei, G Ramponi, CM Dobson Journal of molecular biology 283 (4), 883-891, 1998 | 135 | 1998 |
Solution structure of the pore-forming protein of Entamoeba histolytica O Hecht, NA Van Nuland, K Schleinkofer, AJ Dingley, H Bruhn, M Leippe, ... Journal of Biological Chemistry 279 (17), 17834-17841, 2004 | 129 | 2004 |
An extended sampling of the configurational space of HPr from E. coli BL de Groot, A Amadei, RM Scheek, NAJ Van Nuland, HJC Berendsen Proteins: Structure, Function, and Bioinformatics 26 (3), 314-322, 1996 | 118 | 1996 |
Slow cooperative folding of a small globular protein HPr NAJ Van Nuland, W Meijberg, J Warner, V Forge, RM Scheek, ... Biochemistry 37 (2), 622-637, 1998 | 116 | 1998 |
Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis MB Ekkelenkamp, M Hanssen, STD Hsu, A de Jong, D Milatovic, ... FEBS letters 579 (9), 1917-1922, 2005 | 113 | 2005 |
Mycoredoxin‐1 is one of the missing links in the oxidative stress defence mechanism of M ycobacteria K Van Laer, L Buts, N Foloppe, D Vertommen, K Van Belle, K Wahni, ... Molecular microbiology 86 (4), 787-804, 2012 | 111 | 2012 |
Function, diversity and therapeutic potential of the N-terminal domain of human chemokine receptors M Szpakowska, V Fievez, K Arumugan, N Van Nuland, JC Schmit, ... Biochemical pharmacology 84 (10), 1366-1380, 2012 | 110 | 2012 |
Mapping the targeted membrane pore formation mechanism by solution NMR: the nisin Z and lipid II interaction in SDS micelles ST Hsu, E Breukink, B de Kruijff, R Kaptein, AMJJ Bonvin, ... Biochemistry 41 (24), 7670-7676, 2002 | 102 | 2002 |
The high-resolution structure of the histidine-containing phosphocarrier protein HPr from Escherichia coli determined by restrained molecular dynamics from nuclear magnetic … NAJ van Nuland, IW Hangyi, RC van Schaik, HJC Berendsen, ... Journal of molecular biology 237 (5), 544-559, 1994 | 92 | 1994 |
Transient dynamics of Aβ contribute to toxicity in Alzheimer’s disease E Hubin, NAJ Van Nuland, K Broersen, K Pauwels Cellular and Molecular Life Sciences 71, 3507-3521, 2014 | 91 | 2014 |
High-resolution Structure of the Phosphorylated Form of the Histidine-containing Phosphocarrier Protein HPr fromEscherichia coliDetermined by Restrained Molecular Dynamics from … NAJ van Nuland, R Boelens, RM Scheek, GT Robillard Journal of molecular biology 246 (1), 180-193, 1995 | 88 | 1995 |
The solution structure of a transient photoreceptor intermediate: Δ25 photoactive yellow protein C Bernard, K Houben, NM Derix, D Marks, MA van der Horst, ... Structure 13 (7), 953-962, 2005 | 87 | 2005 |
Real-time NMR studies of protein folding NAJ van Nuland, V Forge, J Balbach, CM Dobson Accounts of chemical research 31 (11), 773-780, 1998 | 77 | 1998 |