Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue AM Grabiec, S Krausz, W De Jager, T Burakowski, D Groot, ME Sanders, ... The journal of immunology 184 (5), 2718-2728, 2010 | 257 | 2010 |
Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay AM Grabiec, O Korchynskyi, PP Tak, KA Reedquist Annals of the rheumatic diseases 71 (3), 424-431, 2012 | 224 | 2012 |
The role of airway macrophages in apoptotic cell clearance following acute and chronic lung inflammation AM Grabiec, T Hussell Seminars in immunopathology 38, 409-423, 2016 | 172 | 2016 |
The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts K Klein, PA Kabala, AM Grabiec, RE Gay, C Kolling, LL Lin, S Gay, ... Annals of the rheumatic diseases 75 (2), 422-429, 2016 | 161 | 2016 |
Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes C Angiolilli, PA Kabala, AM Grabiec, IM Van Baarsen, BS Ferguson, ... Annals of the rheumatic diseases 76 (1), 277-285, 2017 | 150 | 2017 |
The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung T Fujimori, AM Grabiec, M Kaur, TJ Bell, N Fujino, PC Cook, FR Svedberg, ... Mucosal immunology 8 (5), 1021-1030, 2015 | 125 | 2015 |
Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on AM Grabiec, PP Tak, KA Reedquist Arthritis research & therapy 10 (5), 226, 2008 | 100 | 2008 |
Epigenetic regulation in bacterial infections: targeting histone deacetylases AM Grabiec, J Potempa Critical reviews in microbiology 44 (3), 336-350, 2018 | 98 | 2018 |
Function of histone deacetylase inhibitors in inflammation AM Grabiec, PP Tak, KA Reedquist Critical Reviews™ in Immunology 31 (3), 233-263, 2011 | 97 | 2011 |
Inflammatory cytokines epigenetically regulate rheumatoid arthritis fibroblast-like synoviocyte activation by suppressing HDAC5 expression C Angiolilli, AM Grabiec, BS Ferguson, C Ospelt, BM Fernandez, ... Annals of the rheumatic diseases 75 (2), 430-438, 2016 | 83 | 2016 |
Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective … D de Launay, MGH van de Sande, MJH de Hair, AM Grabiec, ... Annals of the rheumatic diseases 71 (3), 415-423, 2012 | 69 | 2012 |
Epigenetic regulation of inflammation in periodontitis: cellular mechanisms and therapeutic potential KT Jurdziński, J Potempa, AM Grabiec Clinical epigenetics 12 (1), 186, 2020 | 64 | 2020 |
JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis AM Grabiec, C Angiolilli, LM Hartkamp, LGM van Baarsen, PP Tak, ... Annals of the Rheumatic Diseases 74 (9), 1763-1771, 2015 | 61 | 2015 |
Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma AM Grabiec, N Denny, JA Doherty, KE Happonen, J Hankinson, ... Journal of Allergy and Clinical Immunology 140 (4), 1144-1146, 2017 | 54 | 2017 |
The ascent of acetylation in the epigenetics of rheumatoid arthritis AM Grabiec, KA Reedquist Nature Reviews Rheumatology 9 (5), 311-318, 2013 | 47 | 2013 |
Axl and MerTK receptor tyrosine kinases maintain human macrophage efferocytic capacity in the presence of viral triggers AM Grabiec, A Goenka, ME Fife, T Fujimori, T Hussell European journal of immunology 48 (5), 855-860, 2018 | 45 | 2018 |
An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness DF Patel, T Peiró, A Shoemark, S Akthar, SA Walker, AM Grabiec, ... Science translational medicine 10 (455), eaaq0693, 2018 | 39 | 2018 |
Reversal of TREM-1 ectodomain shedding and improved bacterial clearance by intranasal metalloproteinase inhibitors G Weiss, C Lai, ME Fife, AM Grabiec, B Tildy, RJ Snelgrove, G Xin, ... Mucosal Immunology 10 (4), 1021-1030, 2017 | 39 | 2017 |
Histone deacetylases in RA: epigenetics and epiphenomena AM Grabiec, KA Reedquist Arthritis research & therapy 12 (5), 142, 2010 | 39 | 2010 |
BET bromodomain inhibitors suppress inflammatory activation of gingival fibroblasts and epithelial cells from periodontitis patients A Maksylewicz, A Bysiek, KB Lagosz, JM Macina, M Kantorowicz, ... Frontiers in immunology 10, 933, 2019 | 36 | 2019 |