Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity D Havrylyuk, B Zimenkovsky, O Vasylenko, L Zaprutko, A Gzella, R Lesyk European journal of medicinal chemistry 44 (4), 1396-1404, 2009 | 398 | 2009 |
New 5-substituted thiazolo [3, 2-b][1, 2, 4] triazol-6-ones: Synthesis and anticancer evaluation R Lesyk, O Vladzimirska, S Holota, L Zaprutko, A Gzella European journal of medicinal chemistry 42 (5), 641-648, 2007 | 210 | 2007 |
A facile synthesis and anticancer activity evaluation of spiro [thiazolidinone-isatin] conjugates D Kaminskyy, D Khyluk, O Vasylenko, L Zaprutko, R Lesyk Scientia pharmaceutica 79 (4), 763-778, 2011 | 114 | 2011 |
Multidirectional efficacy of biologically active nitro compounds included in medicines D Olender, J Żwawiak, L Zaprutko Pharmaceuticals 11 (2), 54, 2018 | 99 | 2018 |
Synthesis of some N-substituted nitroimidazole derivatives as potential antioxidant and antifungal agents D Olender, J Żwawiak, V Lukianchuk, R Lesyk, A Kropacz, A Fojutowski, ... European journal of medicinal chemistry 44 (2), 645-652, 2009 | 98 | 2009 |
Synthesis of new potential anticancer agents based on 4-thiazolidinone and oleanane scaffolds D Kaminskyy, B Bednarczyk-Cwynar, O Vasylenko, O Kazakova, ... Medicinal Chemistry Research 21, 3568-3580, 2012 | 80 | 2012 |
Molecular consortia—Various structural and synthetic concepts for more effective therapeutics synthesis A Pawełczyk, K Sowa-Kasprzak, D Olender, L Zaprutko International journal of molecular sciences 19 (4), 1104, 2018 | 68 | 2018 |
Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (HIMOXOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells N Lisiak, A Paszel-Jaworska, B Bednarczyk-Cwynar, L Zaprutko, ... Chemico-Biological Interactions 208, 47-57, 2014 | 53 | 2014 |
The analgesic and anti-inflammatory effect of new oleanolic acid acyloxyimino derivative B Bednarczyk-Cwynar, L Zaprutko, J Marciniak, G Lewandowski, M Szulc, ... European journal of pharmaceutical sciences 47 (3), 549-555, 2012 | 52 | 2012 |
Recent advances in synthesis and biological activity of triterpenic acylated oximes B Bednarczyk-Cwynar, L Zaprutko Phytochemistry Reviews 14, 203-231, 2015 | 51 | 2015 |
Triterpenoids. Part 21: Oleanolic acid azaderivatives as percutaneous transport promoters L Zaprutko, D Partyka, B Bednarczyk-Cwynar Bioorganic & medicinal chemistry letters 14 (18), 4723-4726, 2004 | 43 | 2004 |
Microwave assisted synthesis of fragrant jasmone heterocyclic analogues A Pawełczyk, L Zaprutko European journal of medicinal chemistry 41 (5), 586-591, 2006 | 41 | 2006 |
Anticancer effect of A-ring or/and C-ring modified oleanolic acid derivatives on KB, MCF-7 and HeLa cell lines B Bednarczyk–Cwynar, L Zaprutko, P Ruszkowski, B Hładoń Organic & Biomolecular Chemistry 10 (11), 2201-2205, 2012 | 38 | 2012 |
Targeting Nrf2-mediated gene transcription by triterpenoids and their derivatives A Loboda, E Rojczyk-Golebiewska, B Bednarczyk-Cwynar, Z Lucjusz, ... Biomolecules & therapeutics 20 (6), 499, 2012 | 37 | 2012 |
Strong and long-lasting antinociceptive and anti-inflammatory conjugate of naturally occurring oleanolic acid and aspirin B Bednarczyk-Cwynar, N Wachowiak, M Szulc, E Kamińska, A Bogacz, ... Frontiers in Pharmacology 7, 202, 2016 | 36 | 2016 |
Anti-COVID drugs: repurposing existing drugs or search for new complex entities, strategies and perspectives A Pawełczyk, L Zaprutko Future Medicinal Chemistry 12 (19), 1743-1757, 2020 | 34 | 2020 |
A brief history of taxol J Żwawiak, L Zaprutko Journal of Medical Science 83 (1), 47-52, 2014 | 33 | 2014 |
Synthesis of triterpenoid acylates: Effective reproduction inhibitors of influenza A (H1N1) and papilloma viruses OB Kazakova, NI Medvedeva, IP Baikova, GA Tolstikov, TV Lopatina, ... Russian journal of bioorganic chemistry 36, 771-778, 2010 | 31 | 2010 |
Nitrogenous triterpene derivatives. 10. Hemisuccinates of some oleanolic acid derivatives and their antiulcer effect U Wrzeciono, I Malecki, J Budzianowski, H Kierylowicz, L Zaprutko, ... Die Pharmazie 40 (8), 542-544, 1985 | 29 | 1985 |
Beckmann rearrangement of oxime obtained from oleanolic acid. Structure elucidation of the initial oxime B Bednarczyk-Cwynar, L Zaprutko, A Froelich Journal of Molecular Structure 1053, 115-121, 2013 | 27 | 2013 |