关注
Thierry BRUN
Thierry BRUN
在 unige.ch 的电子邮件经过验证
标题
引用次数
引用次数
年份
Metabolic fate of glucose in purified islet cells: glucose-regulated anaplerosis in β cells
F Schuit, A De Vos, S Farfari, K Moens, D Pipeleers, T Brun, M Prentki
Journal of Biological Chemistry 272 (30), 18572-18579, 1997
5181997
Mitochondrial dysfunction in pancreatic β cells
S Supale, N Li, T Brun, P Maechler
Trends in Endocrinology & Metabolism 23 (9), 477-487, 2012
3042012
MAFA controls genes implicated in insulin biosynthesis and secretion
H Wang, T Brun, K Kataoka, AJ Sharma, CB Wollheim
Diabetologia 50, 348-358, 2007
2542007
Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1
VM Schwitzgebel, A Mamin, T Brun, B Ritz-Laser, M Zaiko, A Maret, ...
The Journal of Clinical Endocrinology & Metabolism 88 (9), 4398-4406, 2003
2092003
Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E β-cells and human islets through a SIRT1-dependent mechanism
L Vetterli, T Brun, L Giovannoni, D Bosco, P Maechler
Journal of Biological Chemistry 286 (8), 6049-6060, 2011
1962011
The diabetes-linked transcription factor PAX4 promotes β-cell proliferation and survival in rat and human islets
T Brun, I Franklin, L St-Onge, A Biason-Lauber, EJ Schoenle, ...
The Journal of cell biology 167 (6), 1123-1135, 2004
1942004
Long-term exposure of beta-INS cells to high glucose concentrations increases anaplerosis, lipogenesis, and lipogenic gene expression.
E Roche, S Farfari, LA Witters, F Assimacopoulos-Jeannet, S Thumelin, ...
Diabetes 47 (7), 1086-1094, 1998
1881998
Evidence for an anaplerotic/malonyl-CoA pathway in pancreatic β-cell nutrient signaling
T Brun, E Roche, F Assimacopoulos-Jeannet, BE Corkey, KH Kim, ...
Diabetes 45 (2), 190-198, 1996
1791996
Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1).
T Brun, E Roche, KH Kim, M Prentki
Journal of Biological Chemistry 268 (25), 18905-18911, 1993
1701993
Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic β-cell line INS-1
T Brun, F Assimacopoulos-Jeannet, BE Corkey, M Prentki
Diabetes 46 (3), 393-400, 1997
1481997
Increased fat intake during lactation modifies hypothalamic-pituitary-adrenal responsiveness in developing rat pups: a possible role for leptin
G Trottier, KG Koski, T Brun, DJ Toufexis, D Richard, CD Walker
Endocrinology 139 (9), 3704-3711, 1998
1321998
NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion
N Li, B Li, T Brun, C Deffert-Delbouille, Z Mahiout, Y Daali, XJ Ma, ...
Diabetes 61 (11), 2842-2850, 2012
1312012
Transient oxidative stress damages mitochondrial machinery inducing persistent β-cell dysfunction
N Li, T Brun, M Cnop, DA Cunha, DL Eizirik, P Maechler
Journal of Biological Chemistry 284 (35), 23602-23612, 2009
1172009
Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets
BR Gauthier, T Brun, EJ Sarret, H Ishihara, O Schaad, P Descombes, ...
Journal of Biological Chemistry 279 (30), 31121-31130, 2004
1002004
Role of mitochondria in β-cell function and dysfunction
P Maechler, N Li, M Casimir, L Vetterli, F Frigerio, T Brun
The Islets of Langerhans, 193-216, 2010
932010
Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity
A Biason-Lauber, B Boehm, M Lang-Muritano, BR Gauthier, T Brun, ...
Diabetologia 48, 900-905, 2005
872005
A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease.
T Brun, BR Gauthier
Journal of molecular endocrinology 40 (2), 37-45, 2008
722008
The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1
T Brun, KHH He, R Lupi, B Boehm, A Wojtusciszyn, N Sauter, M Donath, ...
Human molecular genetics 17 (4), 478-489, 2008
712008
In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice
KHH He, PI Lorenzo, T Brun, CM Jimenez Moreno, D Aeberhard, ...
Diabetes 60 (6), 1705-1715, 2011
642011
Transcriptional response of pancreatic beta cells to metabolic stimulation: large scale identification of immediate-early and secondary response genes
DA Glauser, T Brun, BR Gauthier, W Schlegel
BMC molecular biology 8, 1-15, 2007
642007
系统目前无法执行此操作,请稍后再试。
文章 1–20