| Mlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonuclease MV Rogacheva, CM Manhart, C Chen, A Guarne, J Surtees, E Alani Journal of Biological Chemistry 289 (9), 5664-5673, 2014 | 158 | 2014 |
| Roles for mismatch repair family proteins in promoting meiotic crossing over CM Manhart, E Alani DNA repair 38, 84-93, 2016 | 121 | 2016 |
| The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans CM Manhart, X Ni, MA White, J Ortega, JA Surtees, E Alani PLoS biology 15 (4), e2001164, 2017 | 74 | 2017 |
| Multiple C-terminal tails within a single E. coli SSB homotetramer coordinate DNA replication and repair E Antony, E Weiland, Q Yuan, CM Manhart, B Nguyen, AG Kozlov, ... Journal of molecular biology 425 (23), 4802-4819, 2013 | 70 | 2013 |
| High-throughput universal DNA curtain arrays for single-molecule fluorescence imaging IF Gallardo, P Pasupathy, M Brown, CM Manhart, DP Neikirk, E Alani, ... Langmuir 31 (37), 10310-10317, 2015 | 64 | 2015 |
| mlh3 mutations in baker’s yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide N Al-Sweel, V Raghavan, A Dutta, VP Ajith, L Di Vietro, N Khondakar, ... PLoS genetics 13 (8), e1006974, 2017 | 37 | 2017 |
| The rate of polymerase release upon filling the gap between Okazaki fragments is inadequate to support cycling during lagging strand synthesis PR Dohrmann, CM Manhart, CD Downey, CS McHenry Journal of Molecular Biology 414 (1), 15-27, 2011 | 36 | 2011 |
| Intrinsically disordered regions regulate both catalytic and non-catalytic activities of the MutLα mismatch repair complex Y Kim, CM Furman, CM Manhart, E Alani, IJ Finkelstein Nucleic Acids Research 47 (4), 1823-1835, 2019 | 35 | 2019 |
| The PriA replication restart protein blocks replicase access prior to helicase assembly and directs template specificity through its ATPase activity CM Manhart, CS McHenry Journal of Biological Chemistry 288 (6), 3989-3999, 2013 | 30 | 2013 |
| Bacteriophage SPP1 DNA replication strategies promote viral and disable host replication in vitro EM Seco, JC Zinder, CM Manhart, A Lo Piano, CS McHenry, S Ayora Nucleic acids research 41 (3), 1711-1721, 2013 | 26* | 2013 |
| Identification of subunit binding positions on a model fork and displacements that occur during sequential assembly of the Escherichia coli primosome CM Manhart, CS McHenry Journal of Biological Chemistry 290 (17), 10828-10839, 2015 | 14 | 2015 |
| DNA replication and mismatch repair safeguard against metabolic imbalances CM Manhart, E Alani Proceedings of the National Academy of Sciences 114 (22), 5561-5563, 2017 | 12 | 2017 |
| Exo1 protects DNA nicks from ligation to promote crossover formation during meiosis M Gioia, L Payero, S Salim, G Fajish V, AF Farnaz, G Pannafino, JJ Chen, ... Plos Biology 21 (4), e3002085, 2023 | 5 | 2023 |
| The mismatch repair endonuclease MutLα tethers duplex regions of DNA together and relieves DNA torsional tension SJ Witte, IM Rosa, BW Collingwood, JM Piscitelli, CM Manhart Nucleic Acids Research 51 (6), 2725-2739, 2023 | 4 | 2023 |
| Exo1-protected DNA nicks direct crossover formation in meiosis M Gioia, L Payero, G Pannafino, JJ Chen, S Salim, G Fajith, AF Farnaz, ... bioRxiv, 2021.08. 29.458102, 2021 | 2 | 2021 |
| Aberrant cytoplasmic localization of MLH1 characterizes a sub-clonal breast cancer cell population that seeds recurrence A Mazumder, JT DeWitt, E Oropeza, N Punturi, D Lozano, ... bioRxiv, 2024.02. 27.582389, 2024 | 1 | 2024 |
| The Mlh1-Pms1 endonuclease uses ATP to preserve DNA discontinuities as strand discrimination signals to facilitate mismatch repair JM Piscitelli, SJ Witte, YS Sakinejad, CM Manhart bioRxiv, 2024.06. 13.598860, 2024 | 1 | 2024 |
| The DNA repair endonuclease MutLalpha is activated by a novel mechanism that promotes action at a distance SJ Witte, IM Rosa, CM Manhart FASEB journal: official publication of the Federation of American Societies …, 2022 | | 2022 |
| DNA repair| DNA Mismatch Repair in Mammals CM Manhart Elsevier, 2021 | | 2021 |
| Identification of Subunit Binding Positions on a Model Fork and Displacements that Occur During Sequential Assembly of the E. coli Primosome CM Manhart, CS McHenry | | 2015 |
Eric AlaniProfessor of Genetics, Cornell University在 cornell.edu 的电子邮件经过验证
