miR-124-3p functions as a tumor suppressor in breast cancer by targeting CBL Y Wang, L Chen, Z Wu, M Wang, F Jin, N Wang, X Hu, Z Liu, CY Zhang, ... BMC cancer 16, 1-9, 2016 | 121 | 2016 |
Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form H Yang, S Yang, L Jing, L Huang, L Chen, X Zhao, W Yang, Y Pan, P Yin, ... Nature communications 11 (1), 2582, 2020 | 68 | 2020 |
Lack of RAN-mediated toxicity in Huntington’s disease knock-in mice S Yang, H Yang, L Huang, L Chen, Z Qin, S Li, XJ Li Proceedings of the National Academy of Sciences 117 (8), 4411-4417, 2020 | 39 | 2020 |
MERTK activation drives osimertinib resistance in EGFR-mutant non–small cell lung cancer D Yan, JM Huelse, D Kireev, Z Tan, L Chen, S Goyal, X Wang, SV Frye, ... The Journal of Clinical Investigation 132 (15), 2022 | 24 | 2022 |
mirTrans: a resource of transcriptional regulation on microRNAs for human cell lines X Hua, R Tang, X Xu, Z Wang, Q Xu, L Chen, E Wingender, J Li, C Zhang, ... Nucleic acids research 46 (D1), D168-D174, 2018 | 23 | 2018 |
Identifying cell-specific microRNA transcriptional start sites X Hua, L Chen, J Wang, J Li, E Wingender Bioinformatics 32 (16), 2403-2410, 2016 | 23 | 2016 |
The novel BET degrader, QCA570, is highly active against the growth of human NSCLC cells and synergizes with osimertinib in suppressing osimertinib-resistant EGFR-mutant NSCLC … C Liu, L Qian, KA Vallega, G Ma, D Zong, L Chen, S Wang, ... American journal of cancer research 12 (2), 779, 2022 | 8 | 2022 |
CeDAR: incorporating cell type hierarchy improves cell type-specific differential analyses in bulk omics data L Chen, Z Li, H Wu Genome biology 24 (1), 37, 2023 | 7 | 2023 |
Subpopulation commensalism promotes Rac1-dependent invasion of single cells via laminin-332 SB Yoon, L Chen, IE Robinson, TO Khatib, RA Arthur, H Claussen, ... Journal of Cell Biology 223 (6), e202308080, 2024 | 1 | 2024 |
scCTS: identifying the cell type-specific marker genes from population-level single-cell RNA-seq L Chen, Z Guo, T Deng, H Wu Genome Biology 25 (1), 269, 2024 | | 2024 |
Deciphering the Cell Type Specific Activities from High-throughput Omics Data L Chen Emory University, 2023 | | 2023 |
Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1 infected women is associated with lower viral loads E El-Badry, L Chen, K Ghneim, Z Li, K Brooks, JW Rhodes, RP Sekaly, ... Frontiers in Immunology 15, 1507530, 0 | | |