Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation S Dimmeler, I Fleming, B Fisslthaler, C Hermann, R Busse, AM Zeiher Nature 399 (6736), 601-605, 1999 | 4453 | 1999 |
Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase I Fleming, R Busse American Journal of Physiology-Regulatory, Integrative and Comparative …, 2003 | 1313 | 2003 |
Cytochrome P450 2C is an EDHF synthase in coronary arteries B Fisslthaler, R Popp, L Kiss, M Potente, DR Harder, I Fleming, R Busse Nature 401 (6752), 493-497, 1999 | 1137 | 1999 |
EDHF: bringing the concepts together R Busse, G Edwards, M Félétou, I Fleming, PM Vanhoutte, AH Weston Trends in pharmacological sciences 23 (8), 374-380, 2002 | 1069 | 2002 |
Phosphorylation of Thr495 Regulates Ca2+/Calmodulin-Dependent Endothelial Nitric Oxide Synthase Activity I Fleming, B Fisslthaler, S Dimmeler, BE Kemp, R Busse Circulation research 88 (11), e68-e75, 2001 | 930 | 2001 |
Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes C Badorff, RP Brandes, R Popp, S Rupp, C Urbich, A Aicher, I Fleming, ... Circulation 107 (7), 1024-1032, 2003 | 878 | 2003 |
Endothelial aging RP Brandes, I Fleming, R Busse Cardiovascular research 66 (2), 286-294, 2005 | 810 | 2005 |
Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway G Julou-Schaeffer, GA Gray, I Fleming, C Schott, JR Parratt, JC Stoclet American Journal of Physiology-Heart and Circulatory Physiology 259 (4 …, 1990 | 679 | 1990 |
Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets B Wang, L Wu, J Chen, L Dong, C Chen, Z Wen, J Hu, I Fleming, ... Signal transduction and targeted therapy 6 (1), 94, 2021 | 617 | 2021 |
Signal transduction of eNOS activation I Fleming, R Busse Cardiovascular research 43 (3), 532-541, 1999 | 605 | 1999 |
Molecular mechanisms underlying the activation of eNOS I Fleming Pflügers Archiv-European Journal of Physiology 459, 793-806, 2010 | 561 | 2010 |
Endothelium-derived hyperpolarizing factor synthase (Cytochrome P450 2C9) is a functionally significant source of reactive oxygen species in coronary arteries I Fleming, UR Michaelis, D Bredenkötter, B Fisslthaler, F Dehghani, ... Circulation research 88 (1), 44-51, 2001 | 543 | 2001 |
Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor J Bauersachs, R Popp, M Hecker, E Sauer, I Fleming, R Busse Circulation 94 (12), 3341-3347, 1996 | 517 | 1996 |
Cytochrome p450 and vascular homeostasis I Fleming Circulation research 89 (9), 753-762, 2001 | 481 | 2001 |
Ultrastructure and molecular histology of rabbit hind-limb collateral artery growth (arteriogenesis) D Scholz, W Ito, I Fleming, E Deindl, A Sauer, M Wiesnet, R Busse, ... Virchows Archiv 436, 257-270, 2000 | 444 | 2000 |
Modulation of the Ca2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium J Vriens, G Owsianik, B Fisslthaler, M Suzuki, A Janssens, T Voets, ... Circulation research 97 (9), 908-915, 2005 | 434 | 2005 |
Endothelial dysfunction coincides with an enhanced nitric oxide synthase expression and superoxide anion production A Bouloumié, J Bauersachs, W Linz, BA Schölkens, G Wiemer, I Fleming, ... Hypertension 30 (4), 934-941, 1997 | 388 | 1997 |
Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress–induced nitric oxide production in native endothelial cells K Ayajiki, M Kindermann, M Hecker, I Fleming, R Busse Circulation research 78 (5), 750-758, 1996 | 385 | 1996 |
Phosphorylation and activation of the endothelial nitric oxide synthase by fluid shear stress Fisslthaler, Dimmeler, Hermann, Busse Acta Physiologica Scandinavica 168 (1), 81-88, 2000 | 380 | 2000 |
Ca2+-Independent Activation of the Endothelial Nitric Oxide Synthase in Response to Tyrosine Phosphatase Inhibitors and Fluid Shear Stress I Fleming, J Bauersachs, B Fisslthaler, R Busse Circulation research 82 (6), 686-695, 1998 | 366 | 1998 |