Lynx1, a cholinergic brake, limits plasticity in adult visual cortex H Morishita, JM Miwa, N Heintz, TK Hensch Science 330 (6008), 1238-1240, 2010 | 446 | 2010 |
lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS JM Miwa, I Ibanez-Tallon, GW Crabtree, R Sanchez, A Sali, LW Role, ... Neuron 23 (1), 105-114, 1999 | 369 | 1999 |
Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1 I Ibañez-Tallon, JM Miwa, HL Wang, NC Adams, GW Crabtree, SM Sine, ... Neuron 33 (6), 893-903, 2002 | 252 | 2002 |
Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses JM Miwa, R Freedman, HA Lester Neuron 70 (1), 20-33, 2011 | 239 | 2011 |
In vivo activation of midbrain dopamine neurons via sensitized, high-affinity α6∗ nicotinic acetylcholine receptors RM Drenan, SR Grady, P Whiteaker, T McClure-Begley, S McKinney, ... Neuron 60 (1), 123-136, 2008 | 235 | 2008 |
The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo JM Miwa, TR Stevens, SL King, BJ Caldarone, I Ibanez-Tallon, C Xiao, ... Neuron 51 (5), 587-600, 2006 | 193 | 2006 |
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery HA Lester, C Xiao, R Srinivasan, CD Son, J Miwa, R Pantoja, ... The AAPS journal 11, 167-177, 2009 | 184 | 2009 |
Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning R Srinivasan, R Pantoja, FJ Moss, EDW Mackey, CD Son, J Miwa, ... Journal of General Physiology 137 (1), 59-79, 2011 | 182 | 2011 |
Cholinergic modulation of locomotion and striatal dopamine release is mediated by α6α4* nicotinic acetylcholine receptors RM Drenan, SR Grady, AD Steele, S McKinney, NE Patzlaff, JM McIntosh, ... Journal of Neuroscience 30 (29), 9877-9889, 2010 | 146 | 2010 |
A role for LYNX2 in anxiety-related behavior AB Tekinay, Y Nong, JM Miwa, I Lieberam, I Ibanez-Tallon, P Greengard, ... Proceedings of the National Academy of Sciences 106 (11), 4477-4482, 2009 | 133 | 2009 |
Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo I Ibañez-Tallon, H Wen, JM Miwa, J Xing, AB Tekinay, F Ono, P Brehm, ... Neuron 43 (3), 305-311, 2004 | 107 | 2004 |
Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response R Srinivasan, CI Richards, C Xiao, D Rhee, R Pantoja, DA Dougherty, ... Molecular pharmacology 81 (6), 759-769, 2012 | 74 | 2012 |
Lynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum WA Nichols, BJ Henderson, C Yu, RL Parker, CI Richards, HA Lester, ... Journal of Biological Chemistry 289 (45), 31423-31432, 2014 | 72 | 2014 |
Optimizing cholinergic tone through lynx modulators of nicotinic receptors: implications for plasticity and nicotine addiction JM Miwa, HA Lester, A Walz Physiology 27 (4), 187-199, 2012 | 66 | 2012 |
Trafficking of α4* nicotinic receptors revealed by superecliptic phluorin: effects of a β4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine CI Richards, R Srinivasan, C Xiao, EDW Mackey, JM Miwa, HA Lester Journal of Biological Chemistry 286 (36), 31241-31249, 2011 | 66 | 2011 |
TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus JI Hurtado-Zavala, B Ramachandran, S Ahmed, R Halder, C Bolleyer, ... Nature communications 8 (1), 15878, 2017 | 56 | 2017 |
Psychiatric drugs bind to classical targets within early exocytotic pathways: therapeutic effects HA Lester, JM Miwa, R Srinivasan Biological psychiatry 72 (11), 907-915, 2012 | 56 | 2012 |
Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus C Xiao, JM Miwa, BJ Henderson, Y Wang, P Deshpande, SL McKinney, ... Journal of Neuroscience 35 (9), 3734-3746, 2015 | 46 | 2015 |
Lynx prototoxins: Roles of endogenous mammalian neurotoxin-like proteins in modulating nicotinic acetylcholine receptor function to influence complex biological processes JM Miwa, KR Anderson, KM Hoffman Frontiers in pharmacology 10, 343, 2019 | 42 | 2019 |
Enhancement in motor learning through genetic manipulation of the Lynx1 gene JM Miwa, A Walz PloS one 7 (11), e43302, 2012 | 42 | 2012 |