Plasmodium chaperonin TRiC/CCT identified as a target of the antihistamine clemastine using parallel chemoproteomic strategy KY Lu, B Quan, K Sylvester, T Srivastava, MC Fitzgerald, ER Derbyshire Proceedings of the National Academy of Sciences 117 (11), 5810-5817, 2020 | 48 | 2020 |
A human proteome microarray identifies that the heterogeneous nuclear ribonucleoprotein K (hnRNP K) recognizes the 5′ terminal sequence of the hepatitis C virus RNA B Fan, KY Lu, FXR Sutandy, YW Chen, K Konan, H Zhu, CC Kao, ... Molecular & Cellular Proteomics 13 (1), 84-92, 2014 | 48 | 2014 |
Tafenoquine: A Step toward Malaria Elimination: Published as part of the Biochemistry series “Biochemistry to Bedside” KY Lu, ER Derbyshire Biochemistry 59 (8), 911-920, 2020 | 41 | 2020 |
Profiling lipid–protein interactions using nonquenched fluorescent liposomal nanovesicles and proteome microarrays KY Lu, SC Tao, TC Yang, YH Ho, CH Lee, CC Lin, HF Juan, HC Huang, ... Molecular & Cellular Proteomics 11 (11), 1177-1190, 2012 | 38 | 2012 |
Identification of Hsp90 inhibitors with anti-Plasmodium activity D Posfai, AL Eubanks, AI Keim, KY Lu, GZ Wang, PF Hughes, N Kato, ... Antimicrobial agents and chemotherapy 62 (4), 10.1128/aac. 01799-17, 2018 | 36 | 2018 |
Discovery of druggable host factors critical to Plasmodium liver-stage infection R Raphemot, M Toro-Moreno, KY Lu, D Posfai, ER Derbyshire Cell chemical biology 26 (9), 1253-1262. e5, 2019 | 34 | 2019 |
Heterogeneous ribonucleoprotein K (hnRNP K) binds miR-122, a mature liver-specific microRNA required for hepatitis C virus replication B Fan, FXR Sutandy, GD Syu, S Middleton, G Yi, KY Lu, CS Chen, ... Molecular & Cellular Proteomics 14 (11), 2878-2886, 2015 | 34 | 2015 |
Phosphatidylinositol 3-phosphate and Hsp70 protect Plasmodium falciparum from heat-induced cell death KY Lu, CFA Pasaje, T Srivastava, DR Loiselle, JC Niles, E Derbyshire Elife 9, e56773, 2020 | 22 | 2020 |
A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity JG Ganley, A Pandey, K Sylvester, KY Lu, M Toro-Moreno, S Rütschlin, ... Cell Chemical Biology 27 (7), 817-826.e5, 2020 | 19 | 2020 |
Plasmodium PK9 inhibitors promote growth of liver-stage parasites R Raphemot, AL Eubanks, M Toro-Moreno, RA Geiger, PF Hughes, KY Lu, ... Cell chemical biology 26 (3), 411-419. e7, 2019 | 15 | 2019 |
Chemoproteomics for Plasmodium parasite drug target discovery KY Lu, C Mansfield, M Fitzgerald, E Derbyshire ChemBioChem, 2021 | 13 | 2021 |
Protein microarrays: flexible tools for scientific innovation J Neiswinger, I Uzoma, E Cox, HS Rho, G Song, C Paul, JS Jeong, KY Lu, ... Cold Spring Harbor Protocols 2016 (10), pdb. top081471, 2016 | 12 | 2016 |
Close the ring to break the cycle: tandem quinolone-alkyne-cyclisation gives access to tricyclic pyrrolo [1, 2-a] quinolin-5-ones with potent anti-protozoal activity D Szamosvári, K Sylvester, P Schmid, KY Lu, ER Derbyshire, T Böttcher Chemical Communications 55 (49), 7009-7012, 2019 | 11 | 2019 |
Overcoming biological barriers to improve treatment of a Staphylococcus aureus wound infection V Papadopoulou, AE Sidders, KY Lu, AZ Velez, PG Durham, DT Bui, ... Cell chemical biology 30 (5), 513-526. e5, 2023 | 8 | 2023 |
Chemoproteomics: Towards global drug target profiling KY Lu ChemBioChem 21 (22), 3189-3191, 2020 | 7 | 2020 |
Antibiotic Tolerance and Treatment Outcomes in Cystic Fibrosis Methicillin-Resistant Staphylococcus aureus Infections KY Lu, NJ Wagner, AZ Velez, A Ceppe, BP Conlon, MS Muhlebach Microbiology Spectrum, https://doi.org/10.1128/spectrum.04, 2022 | 4 | 2022 |
Inflammasome-mediated glucose limitation induces antibiotic tolerance in Staphylococcus aureus JE Beam, NJ Wagner, KY Lu, JB Parsons, VG Fowler, SE Rowe, ... Iscience 26 (10), 2023 | 3 | 2023 |
Characterization of lipid–protein interactions using nonquenched fluorescent liposomal nanovesicles and yeast proteome microarrays KY Lu, CS Chen, J Neiswinger, H Zhu Cold Spring Harbor Protocols 2016 (10), pdb. prot087981, 2016 | 3 | 2016 |
Liposomes in proteome microarrays for the study of lipid protein interactions KY Lu, GD Syu, CS Chen Liposomes Anal Methodol 30 (3), 139, 2016 | 3 | 2016 |
Plasmodium falciparum Chaperones and Stress Response KY Lu Duke University, 2020 | 1 | 2020 |