Androgen-induced TOP2B-mediated double-strand breaks and prostate cancer gene rearrangements MC Haffner, MJ Aryee, A Toubaji, DM Esopi, R Albadine, B Gurel, ... Nature genetics 42 (8), 668-675, 2010 | 635 | 2010 |
Tracking the clonal origin of lethal prostate cancer MC Haffner, T Mosbruger, DM Esopi, H Fedor, CM Heaphy, DA Walker, ... The Journal of clinical investigation 123 (11), 4918-4922, 2013 | 513 | 2013 |
miR-21: an androgen receptor–regulated microRNA that promotes hormone-dependent and hormone-independent prostate cancer growth J Ribas, X Ni, M Haffner, EA Wentzel, AH Salmasi, WH Chowdhury, ... Cancer research 69 (18), 7165-7169, 2009 | 470 | 2009 |
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers MC Haffner, A Chaux, AK Meeker, DM Esopi, J Gerber, LG Pellakuru, ... Oncotarget 2 (8), 627, 2011 | 466 | 2011 |
DNA hypomethylation arises later in prostate cancer progression than CpG island hypermethylation and contributes to metastatic tumor heterogeneity S Yegnasubramanian, MC Haffner, Y Zhang, B Gurel, TC Cornish, Z Wu, ... Cancer research 68 (21), 8954-8967, 2008 | 316 | 2008 |
Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers MC Haffner, IE Kronberger, JS Ross, CE Sheehan, M Zitt, G Mühlmann, ... Human pathology 40 (12), 1754-1761, 2009 | 280 | 2009 |
DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases MJ Aryee, W Liu, JC Engelmann, P Nuhn, M Gurel, MC Haffner, D Esopi, ... Science translational medicine 5 (169), 169ra10-169ra10, 2013 | 258 | 2013 |
Effect of bipolar androgen therapy for asymptomatic men with castration-resistant prostate cancer: results from a pilot clinical study MT Schweizer, ES Antonarakis, H Wang, AS Ajiboye, A Spitz, H Cao, ... Science translational medicine 7 (269), 269ra2-269ra2, 2015 | 242 | 2015 |
ERG gene rearrangements are common in prostatic small cell carcinomas TL Lotan, NS Gupta, W Wang, A Toubaji, MC Haffner, A Chaux, JL Hicks, ... Modern pathology 24 (6), 820-828, 2011 | 218 | 2011 |
Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth J Lin, MC Haffner, Y Zhang, BH Lee, WN Brennen, J Britton, SK Kachhap, ... The Prostate 71 (4), 333-343, 2011 | 202 | 2011 |
Genomic and phenotypic heterogeneity in prostate cancer MC Haffner, W Zwart, MP Roudier, LD True, WG Nelson, JI Epstein, ... Nature Reviews Urology 18 (2), 79-92, 2021 | 186 | 2021 |
Decreased 5-hydroxymethylcytosine is associated with neural progenitor phenotype in normal brain and shorter survival in malignant glioma BA Orr, MC Haffner, WG Nelson, S Yegnasubramanian, CG Eberhart PloS one 7 (7), e41036, 2012 | 186 | 2012 |
Comprehensive evaluation of programmed death-ligand 1 expression in primary and metastatic prostate cancer MC Haffner, G Guner, D Taheri, GJ Netto, DN Palsgrove, Q Zheng, ... The American journal of pathology 188 (6), 1478-1485, 2018 | 135 | 2018 |
Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis B Benzon, SG Zhao, MC Haffner, M Takhar, N Erho, K Yousefi, P Hurley, ... Prostate cancer and prostatic diseases 20 (1), 28-35, 2017 | 131 | 2017 |
Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer K Boudadi, DL Suzman, V Anagnostou, W Fu, B Luber, H Wang, ... Oncotarget 9 (47), 28561, 2018 | 126 | 2018 |
Combination of methylated-DNA precipitation and methylation-sensitive restriction enzymes (COMPARE-MS) for the rapid, sensitive and quantitative detection of DNA methylation S Yegnasubramanian, X Lin, MC Haffner, AM DeMarzo, WG Nelson Nucleic acids research 34 (3), e19-e19, 2006 | 122 | 2006 |
Transcription-induced DNA double strand breaks: both oncogenic force and potential therapeutic target? MC Haffner, AM De Marzo, AK Meeker, WG Nelson, ... Clinical Cancer Research 17 (12), 3858-3864, 2011 | 120 | 2011 |
Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations JM Gerber, JL Gucwa, D Esopi, M Gurel, MC Haffner, M Vala, WG Nelson, ... Oncotarget 4 (5), 715, 2013 | 119 | 2013 |
The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma A Hector, EA Montgomery, C Karikari, MI Canto, KB Dunbar, JS Wang, ... Cancer biology & therapy 10 (10), 1009-1018, 2010 | 108 | 2010 |
Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular colonization MC Haffner, C Weier, MM Xu, A Vaghasia, B Gürel, B Gümüşkaya, ... The Journal of pathology 238 (1), 31-41, 2016 | 94 | 2016 |