| Overcoming the challenges of solid bridging and constriction during Pd-Catalyzed C− N bond formation in microreactors RL Hartman, JR Naber, N Zaborenko, SL Buchwald, KF Jensen Organic Process Research & Development 14 (6), 1347-1357, 2010 | 274 | 2010 |
| Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation T Noël, JR Naber, RL Hartman, JP McMullen, KF Jensen, SL Buchwald Chemical Science 2 (2), 287-290, 2011 | 254 | 2011 |
| Multistep microchemical synthesis enabled by microfluidic distillation RL Hartman, JR Naber, SL Buchwald, KF Jensen Angewandte Chemie 122 (5), 911-915, 2010 | 187 | 2010 |
| Packed-bed reactors for continuous-flow CN cross-coupling JR Naber, SL Buchwald Angew. Chem. Int. Ed 49, 9469-9474, 2010 | 134 | 2010 |
| Palladium‐Catalyzed Stille Cross‐Coupling Reaction of Aryl Chlorides using a Pre‐Milled Palladium Acetate and XPhos Catalyst System JR Naber, SL Buchwald Advanced Synthesis & Catalysis 350 (7‐8), 957-961, 2008 | 112 | 2008 |
| Photon Equivalents as a Parameter for Scaling Photoredox Reactions in Flow: Translation of Photocatalytic C− N Cross‐Coupling from Lab Scale to Multikilogram Scale EB Corcoran, JP McMullen, F Lévesque, MK Wismer, JR Naber Angewandte Chemie International Edition 59 (29), 11964-11968, 2020 | 111 | 2020 |
| Diastereoselective reductive amination of aryl trifluoromethyl ketones and α‐amino esters G Hughes, PN Devine, JR Naber, PD O'Shea, BS Foster, DJ McKay, ... Angewandte Chemie International Edition 46 (11), 1839-1842, 2007 | 63 | 2007 |
| Design of a kilogram scale, plug flow photoreactor enabled by high power LEDs F Lévesque, MJ Di Maso, K Narsimhan, MK Wismer, JR Naber Organic Process Research & Development 24 (12), 2935-2940, 2020 | 58 | 2020 |
| Development of an automated kinetic profiling system with online HPLC for reaction optimization M Christensen, F Adedeji, S Grosser, K Zawatzky, Y Ji, J Liu, JA Jurica, ... Reaction Chemistry & Engineering 4 (9), 1555-1558, 2019 | 52 | 2019 |
| Augmentation of postswelling surgical sealant potential of adhesive hydrogels TM Shazly, AB Baker, JR Naber, A Bon, KJ Van Vliet, ER Edelman Journal of biomedical materials research Part A 95 (4), 1159-1169, 2010 | 47 | 2010 |
| Advancing flow chemistry portability: a simplified approach to scaling up flow chemistry F Lévesque, NJ Rogus, G Spencer, P Grigorov, JP McMullen, ... Organic Process Research & Development 22 (8), 1015-1021, 2018 | 43 | 2018 |
| Development of an organometallic flow chemistry reaction at pilot-plant scale for the manufacture of verubecestat DA Thaisrivongs, JR Naber, NJ Rogus, G Spencer Organic Process Research & Development 22 (3), 403-408, 2018 | 43 | 2018 |
| Using flow to outpace fast proton transfer in an organometallic reaction for the manufacture of verubecestat (MK-8931) DA Thaisrivongs, JR Naber, JP McMullen Organic Process Research & Development 20 (11), 1997-2004, 2016 | 41 | 2016 |
| Stille cross-coupling reactions of aryl mesylates and tosylates using a biarylphosphine based catalyst system JR Naber, BP Fors, X Wu, J Gunn, SL Buchwald Heterocycles 80 (2), 1215, 2009 | 39 | 2009 |
| Development of a green and sustainable manufacturing process for gefapixant citrate (MK-7264) part 1: introduction and process overview H Ren, KM Maloney, K Basu, MJ Di Maso, GR Humphrey, F Peng, ... Organic Process Research & Development 24 (11), 2445-2452, 2020 | 31 | 2020 |
| Studies Toward the Scaling of Gas‐Liquid Photocycloadditions EB Corcoran, F Lévesque, JP McMullen, JR Naber ChemPhotoChem 2 (10), 931-937, 2018 | 25 | 2018 |
| A next generation synthesis of BACE1 inhibitor verubecestat (MK-8931) DA Thaisrivongs, WJ Morris, L Tan, ZJ Song, TW Lyons, JH Waldman, ... Organic letters 20 (6), 1568-1571, 2018 | 25 | 2018 |
| Preclinical experimental and mathematical approaches for assessing effective doses of inhaled drugs, using mometasone to support human dose predictions M Caniga, A Cabal, K Mehta, DS Ross, MA Gil, JD Woodhouse, J Eckman, ... Journal of aerosol medicine and pulmonary drug delivery 29 (4), 362-377, 2016 | 23 | 2016 |
| Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 2: Development of a Robust Process for Phenol Synthesis F Peng, GR Humphrey, KM Maloney, D Lehnherr, M Weisel, F Lévesque, ... Organic Process Research & Development 24 (11), 2453-2461, 2020 | 19 | 2020 |
| One-step synthesis of 2-fluoroadenine using hydrogen fluoride pyridine in a continuous flow operation N Salehi Marzijarani, DR Snead, JP McMullen, F Lévesque, M Weisel, ... Organic Process Research & Development 23 (8), 1522-1528, 2019 | 19 | 2019 |
