Complement and microglia mediate early synapse loss in Alzheimer mouse models S Hong, VF Beja-Glasser, BM Nfonoyim, A Frouin, S Li, S Ramakrishnan, ... Science 352 (6286), 712-716, 2016 | 2702 | 2016 |
Soluble oligomers of amyloid β protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake S Li, S Hong, NE Shepardson, DM Walsh, GM Shankar, D Selkoe Neuron 62 (6), 788-801, 2009 | 1168 | 2009 |
Microglia states and nomenclature: A field at its crossroads RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ... Neuron 110 (21), 3458-3483, 2022 | 669 | 2022 |
New insights on the role of microglia in synaptic pruning in health and disease S Hong, L Dissing-Olesen, B Stevens Current opinion in neurobiology 36, 128-134, 2016 | 585 | 2016 |
Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice Q Shi, S Chowdhury, R Ma, KX Le, S Hong, BJ Caldarone, B Stevens, ... Science translational medicine 9 (392), eaaf6295, 2017 | 486 | 2017 |
Complement C3-deficient mice fail to display age-related hippocampal decline Q Shi, KJ Colodner, SB Matousek, K Merry, S Hong, JE Kenison, JL Frost, ... Journal of Neuroscience 35 (38), 13029-13042, 2015 | 351 | 2015 |
Microglia modulate neurodegeneration in Alzheimer’s and Parkinson’s diseases T Bartels, S De Schepper, S Hong Science 370 (6512), 66-69, 2020 | 277 | 2020 |
Assessing disease onset and progression in the SOD1 mouse model of ALS P Weydt, SY Hong, M Kliot, T Möller Neuroreport 14 (7), 1051-1054, 2003 | 259 | 2003 |
Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes S Hong, BL Ostaszewski, T Yang, TT O’Malley, M Jin, K Yanagisawa, S Li, ... Neuron 82 (2), 308-319, 2014 | 231 | 2014 |
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain SE Marsh, AJ Walker, T Kamath, L Dissing-Olesen, TR Hammond, ... Nature neuroscience 25 (3), 306-316, 2022 | 204 | 2022 |
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia H Fu, B Liu, JL Frost, S Hong, M Jin, B Ostaszewski, GM Shankar, ... Glia 60 (6), 993-1003, 2012 | 188 | 2012 |
Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival P Weydt, S Hong, A Witting, T Möller, N Stella, M Kliot Amyotrophic Lateral Sclerosis 6 (3), 182-184, 2005 | 134 | 2005 |
LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-β peptide in a blood–brain barrier in vitro model B Nazer, S Hong, DJ Selkoe Neurobiology of disease 30 (1), 94-102, 2008 | 132 | 2008 |
New ELISAs with high specificity for soluble oligomers of amyloid β-protein detect natural Aβ oligomers in human brain but not CSF T Yang, S Hong, T O'Malley, RA Sperling, DM Walsh, DJ Selkoe Alzheimer's & Dementia 9 (2), 99-112, 2013 | 128 | 2013 |
Dynamic analysis of amyloid β-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aβ during age-related plaque formation S Hong, O Quintero-Monzon, BL Ostaszewski, DR Podlisny, ... Journal of Neuroscience 31 (44), 15861-15869, 2011 | 122 | 2011 |
Histone deacetylase inhibition modulates kynurenine pathway activation in yeast, microglia, and mice expressing a mutant huntingtin fragment F Giorgini, T Moller, W Kwan, D Zwilling, JL Wacker, S Hong, LCL Tsai, ... Journal of Biological Chemistry 283 (12), 7390-7400, 2008 | 112 | 2008 |
Microglia: phagocytosing to clear, sculpt, and eliminate S Hong, B Stevens Developmental cell 38 (2), 126-128, 2016 | 109 | 2016 |
Endocannabinoids accumulate in spinal cord of SOD1G93A transgenic mice A Witting, P Weydt, S Hong, M Kliot, T Mőller, N Stella Journal of neurochemistry 89 (6), 1555-1557, 2004 | 105 | 2004 |
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease S De Schepper, JZ Ge, G Crowley, LSS Ferreira, D Garceau, CE Toomey, ... Nature neuroscience 26 (3), 406-415, 2023 | 95 | 2023 |
Physical and functional interaction between the α-and γ-secretases: a new model of regulated intramembrane proteolysis AC Chen, S Kim, N Shepardson, S Patel, S Hong, DJ Selkoe Journal of Cell Biology 211 (6), 1157-1176, 2015 | 64 | 2015 |