From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations G Veit, RG Avramescu, AN Chiang, SA Houck, Z Cai, KW Peters, JS Hong, ... Molecular biology of the cell 27 (3), 424-433, 2016 | 603 | 2016 |
Mechanism-based corrector combination restores ΔF508-CFTR folding and function T Okiyoneda, G Veit, JF Dekkers, M Bagdany, N Soya, H Xu, A Roldan, ... Nature chemical biology 9 (7), 444-454, 2013 | 453 | 2013 |
Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression G Veit, RG Avramescu, D Perdomo, PW Phuan, M Bagdany, PM Apaja, ... Science translational medicine 6 (246), 246ra97-246ra97, 2014 | 330 | 2014 |
Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain G Veit, B Kobbe, DR Keene, M Paulsson, M Koch, R Wagener Journal of Biological Chemistry 281 (6), 3494-3504, 2006 | 314 | 2006 |
Type XIV collagen regulates fibrillogenesis HL Ansorge, X Meng, G Zhang, G Veit, M Sun, JF Klement, DP Beason, ... Journal of Biological Chemistry 284 (13), 8427-8438, 2009 | 207 | 2009 |
Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination G Veit, A Roldan, MA Hancock, DF Da Fonte, H Xu, M Hussein, S Frenkiel, ... JCI insight 5 (18), 2020 | 190 | 2020 |
Type XII collagen regulates osteoblast polarity and communication during bone formation Y Izu, M Sun, D Zwolanek, G Veit, V Williams, B Cha, KJ Jepsen, M Koch, ... Journal of Cell Biology 193 (6), 1115-1130, 2011 | 148 | 2011 |
Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in humans and mice Y Zou, D Zwolanek, Y Izu, S Gandhy, G Schreiber, K Brockmann, ... Human molecular genetics 23 (9), 2339-2352, 2014 | 133 | 2014 |
Structure-guided combination therapy to potently improve the function of mutant CFTRs G Veit, H Xu, E Dreano, RG Avramescu, M Bagdany, LK Beitel, A Roldan, ... Nature medicine 24 (11), 1732-1742, 2018 | 131 | 2018 |
Proinflammatory Cytokine Secretion is Suppressed by TMEM16A or CFTR Channel Activity in Human Cystic Fibrosis Bronchial Epithelia G Veit, F Bossard, J Goepp, AS Verkman, LJV Galietta, JW Hanrahan, ... Molecular Biology of the Cell, 2012 | 119 | 2012 |
Collagen XII interacts with avian tenascin-X through its NC3 domain G Veit, U Hansen, DR Keene, P Bruckner, R Chiquet-Ehrismann, ... Journal of biological chemistry 281 (37), 27461-27470, 2006 | 105 | 2006 |
The cysteine-rich domain of snake venom metalloproteinases is a ligand for von Willebrand factor A domains: role in substrate targeting SMT Serrano, J Kim, D Wang, B Dragulev, JD Shannon, HH Mann, G Veit, ... Journal of Biological Chemistry 281 (52), 39746-39756, 2006 | 99 | 2006 |
Synergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy PW Phuan, G Veit, J Tan, A Roldan, WE Finkbeiner, GL Lukacs, ... Molecular pharmacology 86 (1), 42-51, 2014 | 82 | 2014 |
Chaperone-independent peripheral quality control of CFTR by RFFL E3 ligase T Okiyoneda, G Veit, R Sakai, M Aki, T Fujihara, M Higashi, ... Developmental cell 44 (6), 694-708. e7, 2018 | 76 | 2018 |
Expression of type XXIII collagen mRNA and protein M Koch, G Veit, S Stricker, P Bhatt, S Kutsch, P Zhou, E Reinders, ... Journal of Biological Chemistry 281 (30), 21546-21557, 2006 | 74 | 2006 |
Zebrafish collagen XII is present in embryonic connective tissue sheaths (fascia) and basement membranes HL Bader, DR Keene, B Charvet, G Veit, W Driever, M Koch, F Ruggiero Matrix Biology 28 (1), 32-43, 2009 | 69 | 2009 |
Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell M Bagdany, G Veit, R Fukuda, RG Avramescu, T Okiyoneda, I Baaklini, ... Nature communications 8 (1), 398, 2017 | 68 | 2017 |
Elexacaftor co-potentiates the activity of F508del and gating mutants of CFTR G Veit, C Vaccarin, GL Lukacs Journal of Cystic Fibrosis 20 (5), 895-898, 2021 | 67 | 2021 |
Ribosomal stalk protein silencing partially corrects the ΔF508-CFTR functional expression defect G Veit, K Oliver, PM Apaja, D Perdomo, A Bidaud-Meynard, ST Lin, J Guo, ... PLoS biology 14 (5), e1002462, 2016 | 59 | 2016 |
Shedding of collagen XXIII is mediated by furin and depends on the plasma membrane microenvironment G Veit, EP Zimina, CW Franzke, S Kutsch, U Siebolds, MK Gordon, ... Journal of Biological Chemistry 282 (37), 27424-27435, 2007 | 58 | 2007 |