Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease S Morabito, E Miyoshi, N Michael, S Shahin, AC Martini, E Head, J Silva, ... Nature genetics 53 (8), 1143-1155, 2021 | 305 | 2021 |
hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data S Morabito, F Reese, N Rahimzadeh, E Miyoshi, V Swarup Cell reports methods 3 (6), 2023 | 79 | 2023 |
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ... Cell reports 39 (11), 2022 | 68 | 2022 |
Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease S Morabito, E Miyoshi, N Michael, V Swarup Human molecular genetics 29 (17), 2899-2919, 2020 | 62 | 2020 |
Apolipoprotein E/amyloid-β complex accumulates in alzheimer disease cortical synapses via apolipoprotein e receptors and is enhanced by APOE4 T Bilousova, M Melnik, E Miyoshi, BL Gonzalez, WW Poon, HV Vinters, ... The American journal of pathology 189 (8), 1621-1636, 2019 | 45 | 2019 |
Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta E Miyoshi, T Bilousova, M Melnik, D Fakhrutdinov, WW Poon, HV Vinters, ... Laboratory Investigation 101 (12), 1605-1617, 2021 | 41 | 2021 |
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2 T Bilousova, C Elias, E Miyoshi, MP Alam, C Zhu, J Campagna, K Vadivel, ... Biochemical and biophysical research communications 499 (4), 751-757, 2018 | 31 | 2018 |
High dimensional co-expression networks enable discovery of transcriptomic drivers in complex biological systems S Morabito, F Reese, N Rahimzadeh, E Miyoshi, V Swarup Biorxiv, 2022.09. 22.509094, 2022 | 26 | 2022 |
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation RG Lim, O Al-Dalahmah, J Wu, MP Gold, JC Reidling, G Tang, M Adam, ... Nature communications 13 (1), 7791, 2022 | 18 | 2022 |
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer’s Disease E Miyoshi, S Morabito, CM Henningfield, N Rahimzadeh, SK Shabestari, ... bioRxiv, 2023 | 6 | 2023 |
Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits AM Reyes-Ortiz, EM Abud, MS Burns, J Wu, SJ Hernandez, N McClure, ... Iscience 26 (1), 2023 | 5 | 2023 |
Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue Z Shi, S Das, S Morabito, E Miyoshi, V Swarup STAR protocols 3 (3), 101491, 2022 | 5 | 2022 |
Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer's disease and related tauopathies E Miyoshi, S Morabito, V Swarup Neurobiology of disease 160, 105530, 2021 | 5 | 2021 |
Single‐cell multi‐omics analysis identifies dynamic regulation of SREBF1 in Alzheimer’s disease V Swarup, S Morabito, E Miyoshi, N Michael, S Shahin, AC Martini, ... Alzheimer's & Dementia 17, e049956, 2021 | 4 | 2021 |
Single nuclei RNAseq analysis of HD mouse models and human brain reveals impaired oligodendrocyte maturation and potential role for thiamine metabolism RG Lim, O Al-Dalahmah, J Wu, MP Gold, JC Reidling, G Tang, M Adam, ... BioRxiv, 2022.06. 27.497613, 2022 | 3 | 2022 |
Single‐nuclei chromatin accessibility and transcriptomics unravels altered human oligodendrocyte heterogeneity in Alzheimer’s disease: Genetics: Genetics and omics of AD I S Morabito, E Miyoshi, N Michael, S Shahin, V Swarup Alzheimer's & Dementia 16, e036843, 2020 | 2 | 2020 |
Spatiotemporal transcriptomic characterization of an amyloid mouse model of Alzheimer’s disease E Miyoshi, S Morabito, CM Henningfield, N Michael, SK Shabestari, S Das, ... Alzheimer's & Dementia 18, e065285, 2022 | 1 | 2022 |
Rogue gene networks gone awry in Alzheimer's disease E Miyoshi, V Swarup Neural Regeneration Research 16 (12), 2415-2416, 2021 | 1 | 2021 |
Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer’s disease cortex M Melnik, E Miyoshi, R Ma, M Corrada, C Kawas, R Bohannan, ... Journal of Neuroscience Methods 406, 110137, 2024 | | 2024 |
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease LF Garcia‐Agudo, Z Shi, IF Smith, EA Kramár, K Tran, S Kawauchi, ... Alzheimer's & Dementia 20 (4), 2922-2942, 2024 | | 2024 |