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Emily Miyoshi
Emily Miyoshi
Senior Bioinformatics Scientist, n-Lorem
在 uci.edu 的电子邮件经过验证
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引用次数
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Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s disease
S Morabito, E Miyoshi, N Michael, S Shahin, AC Martini, E Head, J Silva, ...
Nature genetics 53 (8), 1143-1155, 2021
3052021
hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data
S Morabito, F Reese, N Rahimzadeh, E Miyoshi, V Swarup
Cell reports methods 3 (6), 2023
792023
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ...
Cell reports 39 (11), 2022
682022
Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease
S Morabito, E Miyoshi, N Michael, V Swarup
Human molecular genetics 29 (17), 2899-2919, 2020
622020
Apolipoprotein E/amyloid-β complex accumulates in alzheimer disease cortical synapses via apolipoprotein e receptors and is enhanced by APOE4
T Bilousova, M Melnik, E Miyoshi, BL Gonzalez, WW Poon, HV Vinters, ...
The American journal of pathology 189 (8), 1621-1636, 2019
452019
Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta
E Miyoshi, T Bilousova, M Melnik, D Fakhrutdinov, WW Poon, HV Vinters, ...
Laboratory Investigation 101 (12), 1605-1617, 2021
412021
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2
T Bilousova, C Elias, E Miyoshi, MP Alam, C Zhu, J Campagna, K Vadivel, ...
Biochemical and biophysical research communications 499 (4), 751-757, 2018
312018
High dimensional co-expression networks enable discovery of transcriptomic drivers in complex biological systems
S Morabito, F Reese, N Rahimzadeh, E Miyoshi, V Swarup
Biorxiv, 2022.09. 22.509094, 2022
262022
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation
RG Lim, O Al-Dalahmah, J Wu, MP Gold, JC Reidling, G Tang, M Adam, ...
Nature communications 13 (1), 7791, 2022
182022
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer’s Disease
E Miyoshi, S Morabito, CM Henningfield, N Rahimzadeh, SK Shabestari, ...
bioRxiv, 2023
62023
Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits
AM Reyes-Ortiz, EM Abud, MS Burns, J Wu, SJ Hernandez, N McClure, ...
Iscience 26 (1), 2023
52023
Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue
Z Shi, S Das, S Morabito, E Miyoshi, V Swarup
STAR protocols 3 (3), 101491, 2022
52022
Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer's disease and related tauopathies
E Miyoshi, S Morabito, V Swarup
Neurobiology of disease 160, 105530, 2021
52021
Single‐cell multi‐omics analysis identifies dynamic regulation of SREBF1 in Alzheimer’s disease
V Swarup, S Morabito, E Miyoshi, N Michael, S Shahin, AC Martini, ...
Alzheimer's & Dementia 17, e049956, 2021
42021
Single nuclei RNAseq analysis of HD mouse models and human brain reveals impaired oligodendrocyte maturation and potential role for thiamine metabolism
RG Lim, O Al-Dalahmah, J Wu, MP Gold, JC Reidling, G Tang, M Adam, ...
BioRxiv, 2022.06. 27.497613, 2022
32022
Single‐nuclei chromatin accessibility and transcriptomics unravels altered human oligodendrocyte heterogeneity in Alzheimer’s disease: Genetics: Genetics and omics of AD I
S Morabito, E Miyoshi, N Michael, S Shahin, V Swarup
Alzheimer's & Dementia 16, e036843, 2020
22020
Spatiotemporal transcriptomic characterization of an amyloid mouse model of Alzheimer’s disease
E Miyoshi, S Morabito, CM Henningfield, N Michael, SK Shabestari, S Das, ...
Alzheimer's & Dementia 18, e065285, 2022
12022
Rogue gene networks gone awry in Alzheimer's disease
E Miyoshi, V Swarup
Neural Regeneration Research 16 (12), 2415-2416, 2021
12021
Simultaneous isolation of intact brain cells and cell-specific extracellular vesicles from cryopreserved Alzheimer’s disease cortex
M Melnik, E Miyoshi, R Ma, M Corrada, C Kawas, R Bohannan, ...
Journal of Neuroscience Methods 406, 110137, 2024
2024
BIN1K358R suppresses glial response to plaques in mouse model of Alzheimer's disease
LF Garcia‐Agudo, Z Shi, IF Smith, EA Kramár, K Tran, S Kawauchi, ...
Alzheimer's & Dementia 20 (4), 2922-2942, 2024
2024
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