| The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. A Inoue, M Yanagisawa, S Kimura, Y Kasuya, T Miyauchi, K Goto, ... Proceedings of the national academy of sciences 86 (8), 2863-2867, 1989 | 3553 | 1989 |
| Primary structure, synthesis, and biological activity of rat endothelin, an endothelium-derived vasoconstrictor peptide. M Yanagisawa, A Inoue, T Ishikawa, Y Kasuya, S Kimura, S Kumagaye, ... Proceedings of the National Academy of Sciences 85 (18), 6964-6967, 1988 | 731 | 1988 |
| Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo J Ishida, T Hashimoto, Y Hashimoto, S Nishiwaki, T Iguchi, S Harada, ... Journal of Biological Chemistry 279 (25), 26274-26279, 2004 | 633 | 2004 |
| Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death H Le-Niculescu, E Bonfoco, Y Kasuya, FX Claret, DR Green, M Karin Molecular and cellular biology 19 (1), 751-763, 1999 | 578 | 1999 |
| Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt K Yamagata, H Daitoku, Y Takahashi, K Namiki, K Hisatake, K Kako, ... Molecular cell 32 (2), 221-231, 2008 | 480 | 2008 |
| Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle. K Goto, Y Kasuya, N Matsuki, Y Takuwa, H Kurihara, T Ishikawa, S Kimura, ... Proceedings of the National Academy of Sciences 86 (10), 3915-3918, 1989 | 480 | 1989 |
| Attenuated defense response and low basal blood pressure in orexin knockout mice Y Kayaba, A Nakamura, Y Kasuya, T Ohuchi, M Yanagisawa, I Komuro, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2003 | 424 | 2003 |
| Endogenous endothelin-1 participates in the maintenance of cardiac function in rats with congestive heart failure: marked increase in endothelin-1 production in the failing heart S Sakai, T Miyauchi, T Sakurai, Y Kasuya, M Ihara, I Yamaguchi, K Goto, ... Circulation 93 (6), 1214-1222, 1996 | 396 | 1996 |
| Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1 S Asada, H Daitoku, H Matsuzaki, T Saito, T Sudo, H Mukai, S Iwashita, ... Cellular signalling 19 (3), 519-527, 2007 | 283 | 2007 |
| Structure-activity relationships of endothelin: importance of the C-terminal moiety S Kimura, Y Kasuya, T Sawamura, O Shinmi, Y Sugita, M Yanagisawa, ... Biochemical and biophysical research communications 156 (3), 1182-1186, 1988 | 258 | 1988 |
| Conversion of big endothelin-1 to 21-residue endothelin-1 is essential for expression of full vasoconstrictor activity: structure-activity relationships of big endothelin-1 S Kimura, Y Kasuya, T Sawamura, O Shinmi, Y Sugita, M Yanagisawa, ... Journal of Cardiovascular Pharmacology 13, S5-7, 1989 | 248 | 1989 |
| Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells. Y Takuwa, Y Kasuya, N Takuwa, M Kudo, M Yanagisawa, K Goto, ... The Journal of clinical investigation 85 (3), 653-658, 1990 | 245 | 1990 |
| Molecular pharmacology and pathophysiological significance of endothelin K Goto, H Hama, Y Kasuya The Japanese Journal of Pharmacology 72 (4), 261-290, 1996 | 220 | 1996 |
| Endothelin-1–Induced Cardiac Hypertrophy Is Inhibited by Activation of Peroxisome Proliferator–Activated Receptor-α Partly Via Blockade of c-Jun NH2-Terminal … Y Irukayama-Tomobe, T Miyauchi, S Sakai, Y Kasuya, T Ogata, ... Circulation 109 (7), 904-910, 2004 | 177 | 2004 |
| Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice K Yanai, T Saito, Y Kakinuma, Y Kon, K Hirota, K Taniguchi-Yanai, ... Journal of Biological Chemistry 275 (1), 5-8, 2000 | 169 | 2000 |
| Endothelin-1 induces vasoconstriction through two functionally distinct pathways in porcine coronary artery: contribution of phosphoinositide turnover Y Kasuya, Y Takuwa, M Yanagisawa, S Kimura, K Goto, T Masaki Biochemical and biophysical research communications 161 (3), 1049-1055, 1989 | 152 | 1989 |
| Up-regulation of CXC chemokines and their receptors: implications for proinflammatory microenvironments of ovarian carcinomas and endometriosis M Furuya, T Suyama, H Usui, Y Kasuya, M Nishiyama, N Tanaka, ... Human pathology 38 (11), 1676-1687, 2007 | 135 | 2007 |
| Molecular identification of guanine‐nucleotide‐binding regulatory proteins which couple to endothelin receptors M Takigawa, T Sakurai, Y Kasuya, Y Abe, T Masaki, K Goto European journal of biochemistry 228 (1), 102-108, 1995 | 133 | 1995 |
| Role of endothelin‐1 in astrocyte responses after acute brain damage H Hama, Y Kasuya, T Sakurai, G Yamada, N Suzuki, T Masaki, K Goto Journal of neuroscience research 47 (6), 590-602, 1997 | 106 | 1997 |
| Action of endothelin-1 on rat astrocytes through the ETB receptor H Hama, T Sakurai, Y Kasuya, M Fujiki, T Masaki, K Goto Biochemical and biophysical research communications 186 (1), 355-362, 1992 | 106 | 1992 |
