The first structure–activity relationship studies for designer receptors exclusively activated by designer drugs X Chen, H Choo, XP Huang, X Yang, O Stone, BL Roth, J Jin ACS chemical neuroscience 6 (3), 476-484, 2015 | 164 | 2015 |
Antiviral activities and cellular toxicities of modified 2′, 3′-dideoxy-2′, 3′-didehydrocytidine analogues LJ Stuyver, S Lostia, M Adams, JS Mathew, BS Pai, J Grier, PM Tharnish, ... Antimicrobial agents and chemotherapy 46 (12), 3854-3860, 2002 | 146 | 2002 |
Inhibition of Hepatitis C Replicon RNA Synthesis by β-D-2′-deoxy-2′-fluoro-2′-C-Methylcytidine: A Specific Inhibitor of Hepatitis C Virus Replication LJ Stuyver, TR McBrayer, PM Tharnish, J Clark, L Hollecker, S Lostia, ... Antiviral chemistry and chemotherapy 17 (2), 79-87, 2006 | 141 | 2006 |
In vitro solubility, stability and permeability of novel quercetin–amino acid conjugates MK Kim, K Park, W Yeo, H Choo, Y Chong Bioorganic & medicinal chemistry 17 (3), 1164-1171, 2009 | 137 | 2009 |
Enantiomeric Synthesis of d- and l-Cyclopentenyl Nucleosides and Their Antiviral Activity Against HIV and West Nile Virus GY Song, V Paul, H Choo, J Morrey, RW Sidwell, RF Schinazi, CK Chu Journal of Medicinal Chemistry 44 (23), 3985-3993, 2001 | 107 | 2001 |
L-nucleosides: antiviral activity and molecular mechanism G Gumina, Y Chong, H Choo, GY Song, CK Chu Current Topics in Medicinal Chemistry 2 (10), 1065-1086, 2002 | 97 | 2002 |
Novel quinazolinone derivatives as 5-HT7 receptor ligands YH Na, SH Hong, JH Lee, WK Park, DJ Baek, HY Koh, YS Cho, H Choo, ... Bioorganic & medicinal chemistry 16 (5), 2570-2578, 2008 | 93 | 2008 |
Stereoselective Synthesis and Antiviral Activity of d-2‘,3‘-Didehydro-2‘,3‘-dideoxy-2‘-fluoro-4‘-thionucleosides Y Chong, H Choo, Y Choi, J Mathew, RF Schinazi, CK Chu Journal of medicinal chemistry 45 (22), 4888-4898, 2002 | 87 | 2002 |
5- and 6-Exocyclic Products, cis-2,3,5-Trisubstituted Tetrahydrofurans, and cis-2,3,6-Trisubstituted Tetrahydropyrans via Prins-Type Cyclization SN Chavre, H Choo, JK Lee, AN Pae, Y Kim, YS Cho The Journal of organic chemistry 73 (19), 7467-7471, 2008 | 77 | 2008 |
Synthesis, Anti-HIV Activity, and Molecular Mechanism of Drug Resistance of l-2‘,3‘-Didehydro-2‘,3‘-dideoxy-2‘-fluoro-4‘-thionucleosides H Choo, Y Chong, Y Choi, J Mathew, RF Schinazi, CK Chu Journal of medicinal chemistry 46 (3), 389-398, 2003 | 71 | 2003 |
Replicon cell culture system as a valuable tool in antiviral drug discovery against hepatitis C virus N Horscroft, VCH Lai, W Cheney, N Yao, JZ Wu, Z Hong, W Zhong Antiviral Chemistry and Chemotherapy 16 (1), 1-12, 2005 | 70 | 2005 |
Benzimidazole derivatives as potent JAK1-selective inhibitors MK Kim, H Shin, K Park, H Kim, J Park, K Kim, J Nam, H Choo, Y Chong Journal of Medicinal Chemistry 58 (18), 7596-7602, 2015 | 69 | 2015 |
2, 6-Bis-arylmethyloxy-5-hydroxychromones with antiviral activity against both hepatitis C virus (HCV) and SARS-associated coronavirus (SCV) MK Kim, MS Yu, HR Park, KB Kim, C Lee, SY Cho, J Kang, H Yoon, ... European journal of medicinal chemistry 46 (11), 5698-5704, 2011 | 68 | 2011 |
A curcumin-based molecular probe for near-infrared fluorescence imaging of tau fibrils in Alzheimer's disease K Park, Y Seo, MK Kim, K Kim, YK Kim, H Choo, Y Chong Organic & biomolecular chemistry 13 (46), 11194-11199, 2015 | 65 | 2015 |
Enhanced stability and intracellular accumulation of quercetin by protection of the chemically or metabolically susceptible hydroxyl groups with a pivaloxymethyl (POM) promoiety MK Kim, KS Park, C Lee, HR Park, H Choo, Y Chong Journal of medicinal chemistry 53 (24), 8597-8607, 2010 | 63 | 2010 |
New Serotonin 5-HT6 Ligands from Common Feature Pharmacophore Hypotheses HJ Kim, MR Doddareddy, H Choo, YS Cho, KT No, WK Park, AN Pae Journal of chemical information and modeling 48 (1), 197-206, 2008 | 63 | 2008 |
Novel GSK-3β inhibitors from sequential virtual screening HJ Kim, H Choo, YS Cho, KT No, AN Pae Bioorganic & medicinal chemistry 16 (2), 636-643, 2008 | 61 | 2008 |
Pharmacokinetic enhancement of the hepatitis C virus protease inhibitors VX-950 and SCH 503034 by co-dosing with ritonavir DJ Kempf, C Klein, HJ Chen, LL Klein, C Yeung, JT Randolph, YY Lau, ... Antiviral Chemistry and Chemotherapy 18 (3), 163-167, 2007 | 60 | 2007 |
Water-soluble and cleavable quercetin–amino acid conjugates as safe modulators for P-glycoprotein-based multidrug resistance MK Kim, H Choo, Y Chong Journal of medicinal chemistry 57 (17), 7216-7233, 2014 | 58 | 2014 |
3D pharmacophore based virtual screening of T-type calcium channel blockers MR Doddareddy, H Choo, YS Cho, H Rhim, HY Koh, JH Lee, SW Jeong, ... Bioorganic & Medicinal Chemistry 15 (2), 1091-1105, 2007 | 58 | 2007 |