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Joseph R Brady
Joseph R Brady
Graduate Research Assistant, Massachusetts Institute of Technology
在 mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
On-demand manufacturing of clinical-quality biopharmaceuticals
LE Crowell, AE Lu, KR Love, A Stockdale, SM Timmick, D Wu, Y Wang, ...
Nature biotechnology 36 (10), 988-995, 2018
1042018
Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice
NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ...
Proceedings of the National Academy of Sciences 118 (38), e2106845118, 2021
782021
Host-Informed Expression of CRISPR Guide RNA for Genomic Engineering in Komagataella phaffii
NC Dalvie, J Leal, CA Whittaker, Y Yang, JR Brady, KR Love, JC Love
ACS synthetic biology 9 (1), 26-35, 2019
502019
Comparative genome‐scale analysis of Pichia pastoris variants informs selection of an optimal base strain
JR Brady, CA Whittaker, MC Tan, DL Kristensen, D Ma, NC Dalvie, ...
Biotechnology and Bioengineering 117 (2), 543-555, 2020
392020
Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters
NC Dalvie, SA Rodriguez-Aponte, BL Hartwell, LH Tostanoski, ...
BioRxiv, 2021
192021
Alternative hosts as the missing link for equitable therapeutic protein production
JR Brady, JC Love
Nature Biotechnology 39 (4), 404-407, 2021
182021
Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
NC Dalvie, JR Brady, LE Crowell, MK Tracey, AM Biedermann, K Kaur, ...
Microbial Cell Factories 20 (1), 94, 2021
162021
Identifying improved sites for heterologous gene integration using ATAC-seq
JR Brady, MC Tan, CA Whittaker, NA Colant, NC Dalvie, KR Love, ...
ACS synthetic biology 9 (9), 2515-2524, 2020
162020
Rapid developability assessments to formulate recombinant protein antigens as stable, low-cost, multi-dose vaccine candidates: Case-study with non-replicating rotavirus (NRRV …
N Sawant, K Kaur, DA Holland, JM Hickey, S Agarwal, JR Brady, ...
Journal of pharmaceutical sciences 110 (3), 1042-1053, 2021
152021
Mechanism of thimerosal-induced structural destabilization of a recombinant rotavirus P [4] protein antigen formulated as a multi-dose vaccine
K Kaur, J Xiong, N Sawant, S Agarwal, JM Hickey, DA Holland, ...
Journal of pharmaceutical sciences 110 (3), 1054-1066, 2021
102021
Stimulation-induced changes at the electrode–tissue interface and their influence on deep brain stimulation
J Evers, K Sridhar, J Liegey, J Brady, H Jahns, M Lowery
Journal of neural engineering 19 (4), 046004, 2022
82022
Constructs and cells for enhanced protein expression
KR Love, JC Love, C Whittaker, J Brady, CB Matthews, N Colant, ...
US Patent App. 16/080,844, 2020
12020
Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffii
Y Yang, NC Dalvie, JR Brady, C Naranjo, T Lorgeree, S Rodriguez, ...
ESS Open Archive eprints 553, 55322456, 2024
2024
Manufacturing of Aglycosylated Monoclonal Antibodies in Yeast
NC Dalvie, JR Brady, C Naranjo, SR Aponte, R Johnston, JC Love
2022 AIChE Annual Meeting, 2022
2022
Modeling of copy number variability in Pichia pastoris
AE Lu, AJ Maloney, NC Dalvie, JR Brady, KR Love, JC Love, RD Braatz
Biotechnology and Bioengineering 118 (5), 1832-1839, 2021
2021
A multi-omics approach to improving productivity of therapeutic proteins in Pichia pastoris (Komagataella phaffii)
JR Brady
Massachusetts Institute of Technology, 2020
2020
Engineering quality and manufacturability of a trivalent protein subunit vaccine
N Dalvie, JR Brady, MK Tracey, L Crowell, DL Kristensen, KR Love, ...
2019 AIChE Annual Meeting, 2019
2019
Optimizing heterologous gene dosage in eukaryotes informed by omic analysis of over 125 yeast strains
J Brady, C Whittaker, M Tan, N Colant, K Love, J Love
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
Leveraging-omics techniques to enhance productivity of biologics in microbes
J Brady, C Whittaker, M Tang, N Colant, N Dalvie, K Love, J Love
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018
2018
Leptospirosis in two squirrel monkeys (Samiri sciureus) [Conference poster].
AM Lee, J Schoening, J Cassidy, J Bainbridge, J Brady, S Peters, ...
2018
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