Structure, function, and pharmacology of NMDA receptor channels V Vyklicky, M Korinek, T Smejkalova, A Balik, B Krausova, M Kaniakova, ... Physiological research 63, S191, 2014 | 394 | 2014 |
Cholesterol modulates open probability and desensitization of NMDA receptors M Korinek, V Vyklicky, J Borovska, K Lichnerova, M Kaniakova, ... The Journal of physiology 593 (10), 2279-2293, 2015 | 102 | 2015 |
Neurosteroid modulation of N-methyl-D-aspartate receptors: molecular mechanism and behavioral effects M Korinek, V Kapras, V Vyklicky, E Adamusova, J Borovska, K Vales, ... Steroids 76 (13), 1409-1418, 2011 | 85 | 2011 |
Access of inhibitory neurosteroids to the NMDA receptor J Borovska, V Vyklicky, E Stastna, V Kapras, B Slavikova, M Horak, ... British journal of pharmacology 166 (3), 1069-1083, 2012 | 77 | 2012 |
Genetically targeted optical control of an endogenous G protein-coupled receptor PC Donthamsetti, J Broichhagen, V Vyklicky, C Stanley, Z Fu, M Visel, ... Journal of the American Chemical Society 141 (29), 11522-11530, 2019 | 64 | 2019 |
Conformational pathway provides unique sensitivity to a synaptic mGluR CH Habrian, J Levitz, V Vyklicky, Z Fu, A Hoagland, I McCort-Tranchepain, ... Nature communications 10 (1), 5572, 2019 | 63 | 2019 |
Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule V Vyklicky, B Krausova, J Cerny, A Balik, M Zapotocky, M Novotny, ... Scientific reports 5 (1), 10935, 2015 | 61 | 2015 |
Surface expression, function, and pharmacology of disease-associated mutations in the membrane domain of the human GluN2B subunit V Vyklicky, B Krausova, J Cerny, M Ladislav, T Smejkalova, B Kysilov, ... Frontiers in molecular neuroscience 11, 110, 2018 | 60 | 2018 |
Key amino acid residues within the third membrane domains of NR1 and NR2 subunits contribute to the regulation of the surface delivery of N-methyl-D-aspartate receptors M Kaniakova, B Krausova, V Vyklicky, M Korinek, K Lichnerova, L Vyklicky, ... Journal of Biological Chemistry 287 (31), 26423-26434, 2012 | 56 | 2012 |
Preferential inhibition of tonically over phasically activated NMDA receptors by pregnane derivatives V Vyklicky, T Smejkalova, B Krausova, A Balik, M Korinek, J Borovska, ... Journal of Neuroscience 36 (7), 2161-2175, 2016 | 53 | 2016 |
A New Class of Potent N-Methyl-d-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications E Kudova, H Chodounska, B Slavikova, M Budesinsky, M Nekardova, ... Journal of medicinal chemistry 58 (15), 5950-5966, 2015 | 39 | 2015 |
Pregnenolone sulfate activates NMDA receptor channels E Adamusova, O Cais, V Vyklicky, E Kudova, H Chodounska, M Horák, ... Physiological Research 62 (6), 731, 2013 | 28 | 2013 |
Positive Modulators of the N-Methyl-d-aspartate Receptor: Structure–Activity Relationship Study of Steroidal 3-Hemiesters B Krausova, B Slavikova, M Nekardova, P Hubalkova, V Vyklicky, ... Journal of medicinal chemistry 61 (10), 4505-4516, 2018 | 27 | 2018 |
Site of action of brain neurosteroid pregnenolone sulfate at the N-methyl-D-aspartate receptor BH Krausova, B Kysilov, J Cerny, V Vyklicky, T Smejkalova, M Ladislav, ... Journal of Neuroscience 40 (31), 5922-5936, 2020 | 26 | 2020 |
Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors SK Adla, B Slavikova, M Smidkova, E Tloustova, M Svoboda, V Vyklicky, ... Steroids 117, 52-61, 2017 | 26 | 2017 |
Total Synthesis of ent-Pregnanolone Sulfate and Its Biological Investigation at the NMDA Receptor V Kapras, V Vyklicky, M Budesinsky, I Cisarova, L Vyklicky, ... Organic letters 20 (4), 946-949, 2018 | 22 | 2018 |
Spectral-and time-resolved phosphorescence of photosensitizers and singlet oxygen: From in vitro towards in vivo V Vyklický, R Dědic, N Curkaniuk, J Hála Journal of luminescence 143, 729-733, 2013 | 19 | 2013 |
Neurosteroid-like Inhibitors of N-Methyl-d-aspartate Receptor: Substituted 2-Sulfates and 2-Hemisuccinates of Perhydrophenanthrene B Slavikova, H Chodounska, M Nekardova, V Vyklicky, M Ladislav, ... Journal of medicinal chemistry 59 (10), 4724-4739, 2016 | 18 | 2016 |
Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation V Vyklicky, C Stanley, C Habrian, EY Isacoff Nature communications 12 (1), 2694, 2021 | 16 | 2021 |
Palmitoylation controls NMDA receptor function and steroid sensitivity P Hubalkova, M Ladislav, V Vyklicky, T Smejkalova, BH Krausova, ... Journal of Neuroscience 41 (10), 2119-2134, 2021 | 16 | 2021 |