Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells GH Mansour, MA El-Magd, DH Mahfouz, IA Abdelhamid, MF Mohamed, ... Bioorganic Chemistry 116, 105329, 2021 | 45 | 2021 |
Biological activities and docking studies on novel Bis 1, 4-DHPS linked to arene core via ether or ester linkage NS Ibrahim, MF Mohamed, AHM Elwahy, IA Abdelhamid Letters in Drug Design & Discovery 15 (10), 1036-1045, 2018 | 44 | 2018 |
Molecular studies on novel antitumor bis 1, 4-dihydropyridine derivatives against lung carcinoma and their limited side effects on normal melanocytes MF Mohamed, NS Ibrahim, AHM Elwahy, IA Abdelhamid Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 34 | 2018 |
Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic … MF Mohamed, FM Sroor, NS Ibrahim, GS Salem, HH El-Sayed, ... Investigational New Drugs 39, 98-110, 2021 | 32 | 2021 |
Design, synthesis, in vitro anticancer, molecular docking and SAR studies of new series of pyrrolo[2,3-d]pyrimidine derivatives FM Sroor, WM Tohamy, KMA Zoheir, NM Abdelazeem, KF Mahrous, ... BMC chemistry 17 (1), 106, 2023 | 15 | 2023 |
Impact of trifluoromethyl and sulfonyl groups on the biological activity of novel aryl-urea derivatives: Synthesis, in-vitro, in-silico and SAR studies FM Sroor, KF Mahrous, HAMA El-Kader, AM Othman, NS Ibrahim Scientific Reports 13 (1), 17560, 2023 | 13 | 2023 |
Synthesis, cytotoxicity and molecular docking simulation of novel bis-1, 4-dihydropyridines linked to aliphatic or arene core via amide or ester-amide linkages AM Abdella, AM Abdelmoniem, NS Ibrahim, SM El-Hallouty, ... Mini Reviews in Medicinal Chemistry 20 (9), 801-816, 2020 | 13 | 2020 |
In silico and in vitro studies of novel cyanoacrylamides incorporating pyrazole moiety against breast and prostate carcinomas FM Sroor, KF Mahrous, HI Shafey, NR Eid, IA Abdelhamid, NS Ibrahim Medicinal Chemistry Research 32 (6), 1190-1203, 2023 | 11 | 2023 |
Cytotoxic Effect of New (E)‐2‐Cyano‐N‐(tetrahydrobenzo[b]thiophen‐2‐yl)acrylamide Derivatives: Down‐Regulation of RBL2 and STAT2 and Triggering of DNA … NS Ibrahim, FM Sroor, KF Mahrous, JA Abd Elaleem, IA Abdelhamid ChemistrySelect 8 (33), e202301754, 2023 | 9 | 2023 |
Novel diphenyl ether-heterocycles hybrids: Synthesis via Hantzsch and Biginelli reactions, molecular docking simulation, and antimicrobial activities YA El-Gabry, ME Salem, NS Ibrahim, AHM Elwahy, IA Abdelhamid, ... Journal of Molecular Structure 1296, 136857, 2024 | 8 | 2024 |
Cytotoxic activity, apoptosis induction and cell cycle arrest in human breast cancer (MCF7) cells by a novel fluorinated tetrahydro-[1, 2, 4] Triazolo [3, 4-a] Isoquinolin … MF Mohamed, NS Ibrahim, SA Ibrahim, MA El-Manawaty, SM El-Hallouty, ... Polycyclic Aromatic Compounds 43 (1), 268-287, 2023 | 8 | 2023 |
Synthesis, molecular docking, and antimicrobial activity of novel scaffolds based on bis (thiazole) linked to 2-phenoxy-N-arylacetamide as new hybrid molecules AH Abdullah, NS Ibrahim, FK Algethami, AHM Elwahy, IA Abdelhamid, ... Journal of Molecular Structure 1302, 137506, 2024 | 7 | 2024 |
Novel Scaffolds Based on Bis-thiazole Connected to Quinoxaline or Thienothiophene through 2-Phenoxy-N-arylacetamide Groups as New Hybrid Molecules … ME Salem, AH Abdullah, NS Ibrahim, MEA Zaki, AHM Elwahy, ... ACS omega 8 (46), 44312-44327, 2023 | 7 | 2023 |
Computational studies and sever apoptotic bioactivity of new heterocyclic cyanoacrylamide based p-fluorophenyl and p-phenolic compounds against liver carcinoma (Hepg2) MF Mohamed, AA Saddiq, TM Al-Shaikh, NS Ibrahim, IA Abdelhamid Bioorganic Chemistry 114, 105147, 2021 | 7 | 2021 |
Synthesis and antibacterial activities of novel hybrid molecules based on benzothiazole, benzimidazole, benzoxazole, and pyrimidine derivatives, each connected to N … AHM Elwahy, HF Hammad, NS Ibrahim, HAS Al-Shamiri, AF Darweesh, ... Journal of Molecular Structure 1307, 137965, 2024 | 6 | 2024 |
Theoretical and molecular mechanistic investigations of novel (3-(furan-2-yl) pyrazol-4-yl) chalcones against lung carcinoma cell line (A549) MF Mohamed, NS Ibrahim, AA Saddiq, OA Almaghrabi, ME Al-Hazemi, ... Naunyn-Schmiedeberg's Archives of Pharmacology 396 (4), 719-736, 2023 | 6 | 2023 |
Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma MF Mohamed, NS Ibrahim, AA Saddiq, IA Abdelhamid Scientific Reports 13 (1), 22486, 2023 | 4 | 2023 |
Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene … NS Ibrahim, HA Sayed, M Sharaky, HM Diab, AHM Elwahy, ... Naunyn-Schmiedeberg's Archives of Pharmacology, 1-17, 2024 | 3 | 2024 |
Synthesis, molecular docking simulation, and antimicrobial activities of novel bis-heterocycles linked to piperazine and vanillin units as novel hybrid molecules via Hantzsch … IMZ Fares, NE Mahmoud, IA Abdelhamid, AHM Elwahy, ... Results in Chemistry 10, 101684, 2024 | 2 | 2024 |
Novel α-Cyano-Indolyl Chalcones as Anti-Cancer Candidates, Induce G1/S Cell Cycle Arrest and Sequentially Activate Caspases-7, 8, and 9 in Breast Carcinoma AA Kashmiry, NS Ibrahim, MF Mohamed, IA Abdelhamid Polycyclic Aromatic Compounds, 1-20, 2024 | 1 | 2024 |