| Single-cell omics analysis reveals functional diversification of hepatocytes during liver regeneration T Chen, S Oh, S Gregory, X Shen, AM Diehl JCI insight 5 (22), 2020 | 60 | 2020 |
| Epithelial splicing regulatory protein 2–mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis J Hyun, Z Sun, AR Ahmadi, S Bangru, UV Chembazhi, K Du, T Chen, ... The Journal of clinical investigation 130 (4), 2129-2145, 2020 | 56 | 2020 |
| Targeting YAP-mediated HSC death susceptibility and senescence for treatment of liver fibrosis K Du, R Maeso-Díaz, SH Oh, E Wang, T Chen, C Pan, K Xiang, RK Dutta, ... Hepatology 77 (6), 1998-2015, 2023 | 22 | 2023 |
| Chromatin remodeling of colorectal cancer liver metastasis is mediated by an HGF‐PU. 1‐DPP4 axis L Wang, E Wang, J Prado Balcazar, Z Wu, K Xiang, Y Wang, Q Huang, ... Advanced Science 8 (19), 2004673, 2021 | 18 | 2021 |
| Integrated chromatin and transcriptomic profiling of patient-derived colon cancer organoids identifies personalized drug targets to overcome oxaliplatin resistance KL Tung, KY Chen, M Negrete, T Chen, A Safi, AA Aljamal, L Song, ... Genes & diseases 8 (2), 203-214, 2021 | 16 | 2021 |
| Aging reduces liver resiliency by dysregulating Hedgehog signaling R Maeso‐Díaz, GD Dalton, S Oh, K Du, L Tang, T Chen, RK Dutta, ... Aging Cell 21 (2), e13530, 2022 | 15 | 2022 |
| Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion NS Giroux, S Ding, MT McClain, TW Burke, E Petzold, HA Chung, ... Scientific reports 12 (1), 11714, 2022 | 11 | 2022 |
| Hepatocyte smoothened activity controls susceptibility to insulin resistance and nonalcoholic fatty liver disease T Chen, G Dalton, SH Oh, R Maeso-Diaz, K Du, RA Meyers, C Guy, ... Cellular and Molecular Gastroenterology and Hepatology 15 (4), 949-970, 2023 | 9 | 2023 |
| Targeting senescent hepatocytes using the thrombomodulin-PAR1 inhibitor vorapaxar ameliorates NAFLD progression R Maeso-Díaz, K Du, C Pan, CD Guy, SH Oh, T Chen, L Wang, DC Ko, ... Hepatology 78 (4), 1209-1222, 2023 | 8 | 2023 |
| Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity NS Giroux, S Ding, MT McClain, TW Burke, E Petzold, HA Chung, ... BioRxiv, 2020 | 3 | 2020 |
| Su1529 SMOOTHENED DEPENDENT HEDGEHOG SIGNALING ENSURES METABOLIC CONTROL BY MAINTAINING AUTOPHAGY AND PROTECTING AGAINST FERROPTOSIS JH Jun, T Chen, G Dalton, S Oh, R Maeso-Diaz, R Dutta, K Du, AM Diehl Gastroenterology 164 (6), S-1317-S-1318, 2023 | | 2023 |
| TARGETING SENESCENT HEPATOCYTES USING THETHBD-PAR1 INHIBITOR VORAPAXAR AMELIORATES NAFLD PROGRESSION K Du, RM Diaz, P Christopher, CD Guy, SH Oh, T Chen, L Tang, RK Dutta, ... HEPATOLOGY 76, S80-S81, 2022 | | 2022 |
| TARGETING YAP-MEDIATED HEPATIC STELLATE CELL DEATH SUSCEPTIBILITY AND SENESCENCE FOR TREATMENT OF LIVER FIBROSIS K Du, RM Diaz, SH Oh, RK Dutta, T Chen, JTA Chi, AM Diehl HEPATOLOGY 76, S50-S51, 2022 | | 2022 |
| Single-Cell Transcriptome Profiling Reveals Hedgehog Critically Regulates Hepatocyte Resiliency T Chen Duke University, 2022 | | 2022 |
| AGING REDUCES LIVER RESILIENCY BY DYSREGULATING HEDGEHOG SIGNALING R Maeso Diaz, GD Dalton, SH Oh, K Du, L Tang, T Chen, AM Diehl HEPATOLOGY 74, 103A-103A, 2021 | | 2021 |
| SINGLE CELL RNA SEQUENCING DATA FROM MICE IDENTIFIES INHIBITED HEDGEHOG SIGNALING IN HEPATOCYTES AS A CRITICAL EARLY EVENT IN HUMAN NAFLD T Chen, GD Dalton, SH Oh, RM Diaz, K Du, RA Myers, SG Gregory, ... HEPATOLOGY 74, 142A-142A, 2021 | | 2021 |
| A Beautiful Day in the Neighborhood: Application of Single‐Cell Transcriptomics to Unravel Liver Cell Heterogeneity in Diseased Human Livers T Chen, AM Diehl Hepatology 74 (2), 547-549, 2021 | | 2021 |
| DYNAMIC EPIGENETIC REPROGRAMMING ENABLES FUNCTIONAL DIVERSIFICATION OF HEPATOCYTES DURING LIVER REGENERATION T Chen, SH Oh, SG Gregory, X Shen, AM Diehl HEPATOLOGY 72, 119A-120A, 2020 | | 2020 |
