Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease J Park, R Shrestha, C Qiu, A Kondo, S Huang, M Werth, M Li, J Barasch, ... Science 360 (6390), 758-763, 2018 | 903 | 2018 |
Mitochondrial damage and activation of the STING pathway lead to renal inflammation and fibrosis KW Chung, P Dhillon, S Huang, X Sheng, R Shrestha, C Qiu, BA Kaufman, ... Cell metabolism 30 (4), 784-799. e5, 2019 | 395 | 2019 |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals A Giri, JN Hellwege, JM Keaton, J Park, C Qiu, HR Warren, ES Torstenson, ... Nature genetics 51 (1), 51-62, 2019 | 375 | 2019 |
Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment L Zhong, L Yao, RJ Tower, Y Wei, Z Miao, J Park, R Shrestha, L Wang, ... Elife 9, e54695, 2020 | 223 | 2020 |
Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets Z Miao, MS Balzer, Z Ma, H Liu, J Wu, R Shrestha, T Aranyi, A Kwan, ... Nature communications 12 (1), 2277, 2021 | 143 | 2021 |
The nuclear receptor ESRRA protects from kidney disease by coupling metabolism and differentiation P Dhillon, J Park, CH Del Pozo, L Li, T Doke, S Huang, J Zhao, HM Kang, ... Cell metabolism 33 (2), 379-394. e8, 2021 | 111 | 2021 |
Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration MS Balzer, T Doke, YW Yang, DL Aldridge, H Hu, H Mai, D Mukhi, Z Ma, ... Nature Communications 13 (1), 4018, 2022 | 78 | 2022 |
Defining the lineage of thermogenic perivascular adipose tissue AR Angueira, AP Sakers, CD Holman, L Cheng, MN Arbocco, F Shamsi, ... Nature metabolism 3 (4), 469-484, 2021 | 76 | 2021 |
Urinary single-cell profiling captures the cellular diversity of the kidney A Abedini, YO Zhu, S Chatterjee, G Halasz, K Devalaraja-Narashimha, ... Journal of the American Society of Nephrology 32 (3), 614-627, 2021 | 74 | 2021 |
Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis T Doke, A Abedini, DL Aldridge, YW Yang, J Park, CM Hernandez, ... Nature immunology 23 (6), 947-959, 2022 | 53 | 2022 |
A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury JY Kim, Y Bai, LA Jayne, RD Hector, AK Persaud, SS Ong, S Rojesh, ... Nature Communications 11 (1), 1924, 2020 | 38 | 2020 |
DNMT1 in Six2 progenitor cells is essential for transposable element silencing and kidney development SY Li, J Park, Y Guan, K Chung, R Shrestha, MB Palmer, K Susztak Journal of the American Society of Nephrology 30 (4), 594-609, 2019 | 36 | 2019 |
Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression A Abedini, J Levinsohn, KA Klötzer, B Dumoulin, Z Ma, J Frederick, ... bioRxiv, 2022.10. 24.513598, 2022 | 20 | 2022 |
Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice YW Yang, B Poudel, J Frederick, P Dhillon, R Shrestha, Z Ma, J Wu, ... Molecular Therapy 30 (7), 2491-2504, 2022 | 12 | 2022 |
Comprehensive single cell RNAseq analysis of the kidney reveals novel cell types and unexpected cell plasticity J Park, R Shrestha, C Qiu, A Kondo, S Huang, M Werth, M Li, J Barasch, ... bioRxiv, 203125, 2017 | 9 | 2017 |
Systematic benchmarking of single-cell ATAC-sequencing protocols FV De Rop, G Hulselmans, C Flerin, P Soler-Vila, A Rafels, V Christiaens, ... Nature biotechnology, 1-11, 2023 | 8 | 2023 |
Single-cell multi-scale footprinting reveals the modular organization of DNA regulatory elements Y Hu, S Ma, VK Kartha, FM Duarte, M Horlbeck, R Zhang, R Shrestha, ... bioRxiv, 2023 | 7 | 2023 |
Induction of IRAK-M in melanoma induces caspase-3 dependent apoptosis by reducing TRAF6 and calpastatin levels D Geng, N Ciavattone, JJ Lasola, R Shrestha, A Sanchez, J Guo, A Vlk, ... Communications Biology 3 (1), 306, 2020 | 6 | 2020 |
Unified mouse and human kidney single-cell expression atlas reveal commonalities and differences in disease states J Zhou, A Abedini, MS Balzer, R Shrestha, P Dhillon, H Liu, H Hu, ... Journal of the American Society of Nephrology 34 (11), 1843-1862, 2023 | 5 | 2023 |
Single cell resolution regulatory landscape of the mouse kidney highlights cellular differentiation programs and renal disease targets Z Miao, MS Balzer, Z Ma, H Liu, J Wu, R Shrestha, T Aranyi, A Kwan, ... bioRxiv, 2020.05. 24.113910, 2020 | 3 | 2020 |