Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial N Sprigg, K Flaherty, JP Appleton, RAS Salman, D Bereczki, M Beridze, ... The Lancet 391 (10135), 2107-2115, 2018 | 372 | 2018 |
Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a … PM Bath, LJ Woodhouse, JP Appleton, M Beridze, H Christensen, ... The Lancet 391 (10123), 850-859, 2018 | 159 | 2018 |
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial RAS Salman, MS Dennis, PAG Sandercock, CLM Sudlow, JM Wardlaw, ... The Lancet 393 (10191), 2613-2623, 2019 | 157 | 2019 |
Prehospital transdermal glyceryl trinitrate in patients with ultra-acute presumed stroke (RIGHT-2): an ambulance-based, randomised, sham-controlled, blinded, phase 3 trial PM Bath, P Scutt, CS Anderson, JP Appleton, E Berge, L Cala, M Dixon, ... The Lancet 393 (10175), 1009-1020, 2019 | 141 | 2019 |
Hypercholesterolaemia and vascular dementia JP Appleton, P Scutt, N Sprigg, PM Bath Clinical Science 131 (14), 1561-1578, 2017 | 138 | 2017 |
Nitric oxide donors (nitrates), L‐arginine, or nitric oxide synthase inhibitors for acute stroke PMW Bath, K Krishnan, JP Appleton Cochrane Database of Systematic Reviews, 2017 | 121 | 2017 |
Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data G Thomalla, F Boutitie, H Ma, M Koga, P Ringleb, LH Schwamm, O Wu, ... The Lancet 396 (10262), 1574-1584, 2020 | 112 | 2020 |
Blood pressure management in acute stroke JP Appleton, N Sprigg, PM Bath Stroke and Vascular Neurology 1 (2), 2016 | 100 | 2016 |
Clinical neurology: why this still matters in the 21st century DJ Nicholl, JP Appleton Journal of Neurology, Neurosurgery & Psychiatry 86 (2), 229-233, 2015 | 95 | 2015 |
Imaging markers of small vessel disease and brain frailty, and outcomes in acute stroke JP Appleton, LJ Woodhouse, A Adami, JL Becker, E Berge, LA Cala, ... Neurology 94 (5), e439-e452, 2020 | 85 | 2020 |
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART … RAS Salman, DP Minks, D Mitra, MA Rodrigues, P Bhatnagar, ... The Lancet Neurology 18 (7), 643-652, 2019 | 75 | 2019 |
Cilostazol for secondary prevention of stroke and cognitive decline: systematic review and meta-analysis C McHutchison, GW Blair, JP Appleton, FM Chappell, F Doubal, PM Bath, ... Stroke 51 (8), 2374-2385, 2020 | 67 | 2020 |
Noncontrast computed tomography signs as predictors of hematoma expansion, clinical outcome, and response to tranexamic acid in acute intracerebral hemorrhage ZK Law, A Ali, K Krishnan, A Bischoff, JP Appleton, P Scutt, L Woodhouse, ... Stroke 51 (1), 121-128, 2020 | 53 | 2020 |
Blood pressure in acute stroke: to treat or not to treat: that is still the question PM Bath, JP Appleton, K Krishnan, N Sprigg Stroke 49 (7), 1784-1790, 2018 | 47 | 2018 |
The TOS study: can we use our patients to help improve clinical assessment? DJ Nicholl, CP Yap, V Cahill, J Appleton, E Willetts, S Sturman The journal of the Royal College of Physicians of Edinburgh 42 (4), 306-310, 2012 | 43 | 2012 |
Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non … RAS Salman, C Keerie, J Stephen, S Lewis, J Norrie, MS Dennis, ... The Lancet Neurology 20 (10), 842-853, 2021 | 42 | 2021 |
Prehospital transdermal glyceryl trinitrate for ultra-acute intracerebral hemorrhage: data from the RIGHT-2 trial PM Bath, LJ Woodhouse, K Krishnan, JP Appleton, CS Anderson, ... Stroke 50 (11), 3064-3071, 2019 | 38 | 2019 |
Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: the … GW Blair, JP Appleton, K Flaherty, F Doubal, N Sprigg, R Dooley, ... EClinicalMedicine 11, 34-43, 2019 | 37 | 2019 |
Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in … JP Appleton, P Scutt, M Dixon, H Howard, L Haywood, D Havard, ... International Journal of Stroke 14 (2), 191-206, 2019 | 29 | 2019 |
Effects of antiplatelet therapy after stroke caused by intracerebral hemorrhage: extended follow-up of the RESTART randomized clinical trial RAS Salman, MS Dennis, PAG Sandercock, CLM Sudlow, JM Wardlaw, ... JAMA neurology 78 (10), 1179-1186, 2021 | 28 | 2021 |