Conditional expression of heterozygous or homozygous Jak2V617F from its endogenous promoter induces a polycythemia vera–like disease H Akada, D Yan, H Zou, S Fiering, RE Hutchison, MG Mohi Blood, The Journal of the American Society of Hematology 115 (17), 3589-3597, 2010 | 284 | 2010 |
Combining the allosteric inhibitor asciminib with ponatinib suppresses emergence of and restores efficacy against highly resistant BCR-ABL1 mutants CA Eide, MS Zabriskie, SLS Stevens, O Antelope, NA Vellore, H Than, ... Cancer Cell 36 (4), 431-443. e5, 2019 | 176 | 2019 |
Characterization of a DRE-binding transcription factor from a halophyte Atriplex hortensis YG Shen, WK Zhang, DQ Yan, BX Du, JS Zhang, Q Liu, SY Chen Theoretical and Applied Genetics 107, 155-161, 2003 | 167 | 2003 |
Age-related mutations and chronic myelomonocytic leukemia CC Mason, JS Khorashad, SK Tantravahi, TW Kelley, MS Zabriskie, ... Leukemia 30 (4), 906-913, 2016 | 143 | 2016 |
Critical requirement for Stat5 in a mouse model of polycythemia vera D Yan, RE Hutchison, G Mohi Blood, The Journal of the American Society of Hematology 119 (15), 3539-3549, 2012 | 141 | 2012 |
A salt-responsive receptor-like kinase gene regulated by the ethylene signaling pathway encodes a plasma membrane serine/threonine kinase XJ He, ZG Zhang, DQ Yan, JS Zhang, SY Chen Theoretical and Applied Genetics 109, 377-383, 2004 | 94 | 2004 |
Autocrine Tnf signaling favors malignant cells in myelofibrosis in a Tnfr2-dependent fashion WL Heaton, AV Senina, AD Pomicter, ME Salama, PM Clair, D Yan, ... Leukemia 32 (11), 2399-2411, 2018 | 48 | 2018 |
SIRT5 is a druggable metabolic vulnerability in acute myeloid leukemia D Yan, A Franzini, AD Pomicter, BJ Halverson, O Antelope, CC Mason, ... Blood cancer discovery 2 (3), 266-287, 2021 | 43 | 2021 |
Differential biological activity of disease-associated JAK2 mutants H Zou, D Yan, G Mohi FEBS letters 585 (7), 1007-1013, 2011 | 37 | 2011 |
Novel halophyte EREBP/AP2_type DNA binding protein improves salt tolerance in transgenic tobacco S Yi-Guo, YAN Dong-Qing, Z Wan-Ke, DU Bao-Xin, Z Jin-Song, LIU Qiang, ... Journal of Integrative Plant Biology 45 (1), 82, 2003 | 37 | 2003 |
JAK2 ex13InDel drives oncogenic transformation and is associated with chronic eosinophilic leukemia and polycythemia vera AB Patel, A Franzini, E Leroy, SJ Kim, AD Pomicter, L Genet, M Xiao, ... Blood, The Journal of the American Society of Hematology 134 (26), 2388-2398, 2019 | 33 | 2019 |
The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations A Franzini, AD Pomicter, D Yan, JS Khorashad, SK Tantravahi, H Than, ... Blood Advances 3 (20), 2949-2961, 2019 | 33 | 2019 |
Nuclear–cytoplasmic transport is a therapeutic target in myelofibrosis D Yan, AD Pomicter, S Tantravahi, CC Mason, AV Senina, JM Ahmann, ... Clinical Cancer Research 25 (7), 2323-2335, 2019 | 33 | 2019 |
Overexpression of proline transporter gene isolated from halophyte confers salt tolerance in Arabidopsis S Yi-Guo, Z Wan-Ke, YAN Dong-Qing, DU Bao-Xing, Z Jin-Song, ... Journal of Integrative Plant Biology 44 (8), 956, 2002 | 28 | 2002 |
STAT3 mutations are not sufficient to induce large granular lymphocytic leukaemia in mice A Dutta, D Yan, RE Hutchison, G Mohi British journal of haematology 180 (6), 911, 2018 | 22 | 2018 |
Deletion of Stat3 enhances myeloid cell expansion and increases the severity of myeloproliferative neoplasms in Jak2V617F knock-in mice D Yan, F Jobe, RE Hutchison, G Mohi Leukemia 29 (10), 2050-2061, 2015 | 20 | 2015 |
MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis H Zhao, AD Pomicter, AM Eiring, A Franzini, J Ahmann, JY Hwang, ... Blood, The Journal of the American Society of Hematology 139 (5), 761-778, 2022 | 12 | 2022 |
Extreme mutational selectivity of axitinib limits its potential use as a targeted therapeutic for BCR-ABL1-positive leukemia MS Zabriskie, CA Eide, D Yan, NA Vellore, AD Pomicter, SL Savage, ... Leukemia 30 (6), 1418-1421, 2016 | 11 | 2016 |
Tyrosine 201 is required for constitutive activation of JAK2V617F and efficient induction of myeloproliferative disease in mice D Yan, RE Hutchison, G Mohi Blood, The Journal of the American Society of Hematology 120 (9), 1888-1898, 2012 | 11 | 2012 |
Dasatinib overcomes stroma-based resistance to the FLT3 inhibitor quizartinib using multiple mechanisms AB Patel, AD Pomicter, D Yan, AM Eiring, O Antelope, JA Schumacher, ... Leukemia 34 (11), 2981-2991, 2020 | 10 | 2020 |