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Charles M Baum
Charles M Baum
Mirati Therapeutics
在 mirati.com 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
RJ Motzer, TE Hutson, P Tomczak, MD Michaelson, RM Bukowski, O Rixe, ...
New England Journal of Medicine 356 (2), 115-124, 2007
72802007
Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial
GD Demetri, AT van Oosterom, CR Garrett, ME Blackstein, MH Shah, ...
The Lancet 368 (9544), 1329-1338, 2006
32552006
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal …
RJ Motzer, MD Michaelson, BG Redman, GR Hudes, G Wilding, RA Figlin, ...
Journal of Clinical Oncology 24 (1), 16-24, 2006
21602006
Sunitinib in patients with metastatic renal cell carcinoma
RJ Motzer, BI Rini, RM Bukowski, BD Curti, DJ George, GR Hudes, ...
Jama 295 (21), 2516-2524, 2006
16342006
Isolation of a candidate human hematopoietic stem-cell population.
CM Baum, IL Weissman, AS Tsukamoto, AM Buckle, B Peault
Proceedings of the National Academy of Sciences 89 (7), 2804-2808, 1992
15521992
Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor
MC Heinrich, RG Maki, CL Corless, CR Antonescu, A Harlow, D Griffith, ...
Journal of clinical oncology 26 (33), 5352-5359, 2008
9882008
Activity of sunitinib in patients with advanced neuroendocrine tumors
MH Kulke, HJ Lenz, NJ Meropol, J Posey, DP Ryan, J Picus, E Bergsland, ...
Journal of Clinical Oncology 26 (20), 3403-3410, 2008
7652008
Human hematopoietic stem cell
A Tsukamoto, CM Baum, Y Aihara, I Weissman
US Patent 5,061,620, 1991
667*1991
Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
HJ Burstein, AD Elias, HS Rugo, MA Cobleigh, AC Wolff, PD Eisenberg, ...
Journal of Clinical Oncology 26 (11), 1810-1816, 2008
6472008
Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins
SE DePrimo, CL Bello, J Smeraglia, CM Baum, D Spinella, BI Rini, ...
Journal of translational medicine 5, 1-11, 2007
3862007
Prognostic nomogram for sunitinib in patients with metastatic renal cell carcinoma
RJ Motzer, RM Bukowski, RA Figlin, TE Hutson, MD Michaelson, ST Kim, ...
Cancer: Interdisciplinary International Journal of the American Cancer …, 2008
2732008
Implantation and maintenance of functional human bone marrow in SCID-hu mice
S Kyoizumi, CM Baum, H Kaneshima, JM McCune, EJ Yee, R Namikawa
2611992
Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor
A Norden-Zfoni, J Desai, J Manola, P Beaudry, J Force, R Maki, ...
Clinical Cancer Research 13 (9), 2643-2650, 2007
2502007
Phase III randomized trial of sunitinib malate (SU11248) versus interferon-alfa (IFN-α) as first-line systemic therapy for patients with metastatic renal cell carcinoma (mRCC)
RJ Motzer, TE Hutson, P Tomczak, MD Michaelson, RM Bukowski, O Rixe, ...
Journal of Clinical Oncology 24 (18_suppl), LBA3-LBA3, 2006
2042006
Lymphoid reconstitution of the human fetal thymus in SCID mice with CD34+ precursor cells.
B Peault, IL Weissman, C Baum, JM McCune, A Tsukamoto
The Journal of experimental medicine 174 (5), 1283-1286, 1991
1821991
Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure
GD Demetri, MC Heinrich, JA Fletcher, CDM Fletcher, ...
Clinical Cancer Research 15 (18), 5902-5909, 2009
1782009
Human hematopoietic stem cell
A Tsukamoto, CM Baum, Y Aihara, I Weissman
US Patent 5,716,827, 1998
1701998
Phase 3, multicenter, randomized, double-blind, placebo-controlled trial of SU11248 in patients (pts) following failure of imatinib for metastatic GIST
GD Demetri, AT Van Oosterom, M Blackstein, C Garrett, M Shah, ...
Journal of Clinical Oncology 23 (16_suppl), 4000-4000, 2005
1672005
SU11248, a multi-targeted tyrosine kinase inhibitor, can overcome imatinib (IM) resistance caused by diverse genomic mechanisms in patients (pts) with metastatic …
GD Demetri, J Desai, JA Fletcher, JA Morgan, CDM Fletcher, ...
Journal of Clinical Oncology 22 (14_suppl), 3001-3001, 2004
1662004
Phase 2 trials of SU11248 show antitumor activity in second-line therapy for patients with metastatic renal cell carcinoma (RCC)
RJ Motzer, BI Rini, MD Michaelson, BG Redman, GR Hudes, G Wilding, ...
Journal of Clinical Oncology 23 (16_suppl), 4508-4508, 2005
1632005
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