The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin P Bargagna-Mohan, A Hamza, Y Kim, YKA Ho, N Mor-Vaknin, ... Chemistry & biology 14 (6), 623-634, 2007 | 366 | 2007 |
Most efficient cocaine hydrolase designed by virtual screening of transition states F Zheng, W Yang, MC Ko, J Liu, H Cho, D Gao, M Tong, HH Tai, ... Journal of the American Chemical Society 130 (36), 12148-12155, 2008 | 204 | 2008 |
Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp. TJ507A Z Hu, Y Wu, S Xie, W Sun, Y Guo, XN Li, J Liu, H Li, J Wang, Z Luo, Y Xue, ... Organic letters 19 (1), 258-261, 2017 | 116 | 2017 |
Combined 3D-QSAR modeling and molecular docking study on indolinone derivatives as inhibitors of 3-phosphoinositide-dependent protein kinase-1 MDM AbdulHameed, A Hamza, J Liu, CG Zhan Journal of chemical information and modeling 48 (9), 1760-1772, 2008 | 108 | 2008 |
Design, preparation, and characterization of high-activity mutants of human butyrylcholinesterase specific for detoxification of cocaine L Xue, MC Ko, M Tong, W Yang, S Hou, L Fang, J Liu, F Zheng, JH Woods, ... Molecular pharmacology 79 (2), 290-297, 2011 | 107 | 2011 |
Bioactive Acylphloroglucinols with Adamantyl Skeleton from Hypericum sampsonii H Zhu, C Chen, J Yang, XN Li, J Liu, B Sun, SX Huang, D Li, G Yao, Z Luo, ... Organic letters 16 (24), 6322-6325, 2014 | 100 | 2014 |
A highly efficient cocaine-detoxifying enzyme obtained by computational design F Zheng, L Xue, S Hou, J Liu, M Zhan, W Yang, CG Zhan Nature communications 5 (1), 3457, 2014 | 89 | 2014 |
Filicinic Acid Based Meroterpenoids with Anti-Epstein–Barr Virus Activities from Hypericum japonicum L Hu, Y Zhang, H Zhu, J Liu, H Li, XN Li, W Sun, J Zeng, Y Xue, Y Zhang Organic letters 18 (9), 2272-2275, 2016 | 72 | 2016 |
Reaction Pathway and Free Energy Profile for Papain-Catalyzed Hydrolysis of N-Acetyl-Phe-Gly 4-Nitroanilide D Wei, X Huang, J Liu, M Tang, CG Zhan Biochemistry 52 (30), 5145-5154, 2013 | 69 | 2013 |
Asperversiamides, Linearly Fused Prenylated Indole Alkaloids from the Marine-Derived Fungus Aspergillus versicolor H Li, W Sun, M Deng, Q Zhou, J Wang, J Liu, C Chen, C Qi, Z Luo, Y Xue, ... The Journal of Organic Chemistry 83 (15), 8483-8492, 2018 | 68 | 2018 |
Spiroaspertrione A, a bridged spirocyclic meroterpenoid, as a potent potentiator of oxacillin against methicillin-resistant Staphylococcus aureus from Aspergillus sp. TJ23 Y He, Z Hu, W Sun, Q Li, XN Li, H Zhu, J Huang, J Liu, J Wang, Y Xue, ... The Journal of Organic Chemistry 82 (6), 3125-3131, 2017 | 68 | 2017 |
(±)-Acortatarinowins A–F, Norlignan, Neolignan, and Lignan Enantiomers from Acorus tatarinowii Y Lu, Y Xue, J Liu, G Yao, D Li, B Sun, J Zhang, Y Liu, C Qi, M Xiang, ... Journal of Natural Products 78 (9), 2205-2214, 2015 | 68 | 2015 |
Armochaetoglobins A–J: Cytochalasan Alkaloids from Chaetomium globosum TW1-1, a Fungus Derived from the Terrestrial Arthropod Armadillidium vulgare C Chen, J Wang, J Liu, H Zhu, B Sun, J Wang, J Zhang, Z Luo, G Yao, ... Journal of Natural Products 78 (6), 1193-1201, 2015 | 68 | 2015 |
Structural revisions of a class of natural products: scaffolds of aglycon analogues of fusicoccins and cotylenins isolated from fungi Y Tang, Y Xue, G Du, J Wang, J Liu, B Sun, XN Li, G Yao, Z Luo, Y Zhang Angewandte Chemie 128 (12), 4137-4141, 2016 | 64 | 2016 |
Design of high-activity mutants of human butyrylcholinesterase against (−)-cocaine: structural and energetic factors affecting the catalytic efficiency F Zheng, W Yang, L Xue, S Hou, J Liu, CG Zhan Biochemistry 49 (42), 9113-9119, 2010 | 63 | 2010 |
Free energies of solvation with surface, volume, and local electrostatic effects and atomic surface tensions to represent the first solvation shell J Liu, CP Kelly, AC Goren, AV Marenich, CJ Cramer, DG Truhlar, ... Journal of chemical theory and computation 6 (4), 1109-1117, 2010 | 62 | 2010 |
Lignans from the Fruit of Schisandra glaucescens with Antioxidant and Neuroprotective Properties HY Yu, ZY Chen, B Sun, J Liu, FY Meng, Y Liu, T Tian, A Jin, HL Ruan Journal of natural products 77 (6), 1311-1320, 2014 | 61 | 2014 |
Fundamental reaction mechanism and free energy profile for (−)-cocaine hydrolysis catalyzed by cocaine esterase J Liu, A Hamza, CG Zhan Journal of the American Chemical Society 131 (33), 11964-11975, 2009 | 58 | 2009 |
Tricyclic Polyprenylated Acylphloroglucinols from St John’s Wort, Hypericum perforatum Y Guo, N Zhang, C Chen, J Huang, XN Li, J Liu, H Zhu, Q Tong, J Zhang, ... Journal of Natural Products 80 (5), 1493-1504, 2017 | 57 | 2017 |
Protoilludane, Illudalane, and Botryane Sesquiterpenoids from the Endophytic Fungus Phomopsis sp. TJ507A S Xie, Y Wu, Y Qiao, Y Guo, J Wang, Z Hu, Q Zhang, X Li, J Huang, ... Journal of natural products 81 (6), 1311-1320, 2018 | 55 | 2018 |