Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism T Ha, AY Ting, J Liang, WB Caldwell, AA Deniz, DS Chemla, PG Schultz, ... Proceedings of the National Academy of Sciences 96 (3), 893-898, 1999 | 719 | 1999 |
Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of Förster distance dependence and subpopulations AA Deniz, M Dahan, JR Grunwell, T Ha, AE Faulhaber, DS Chemla, ... Proceedings of the National Academy of Sciences 96 (7), 3670-3675, 1999 | 694 | 1999 |
Single-molecule protein folding: diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2 AA Deniz, TA Laurence, GS Beligere, M Dahan, AB Martin, DS Chemla, ... Proceedings of the National Academy of Sciences 97 (10), 5179-5184, 2000 | 584 | 2000 |
Interplay of α-synuclein binding and conformational switching probed by single-molecule fluorescence ACM Ferreon, Y Gambin, EA Lemke, AA Deniz Proceedings of the National Academy of Sciences 106 (14), 5645-5650, 2009 | 451 | 2009 |
Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA DM Mitrea, JA Cika, CS Guy, D Ban, PR Banerjee, CB Stanley, A Nourse, ... elife 5, e13571, 2016 | 440 | 2016 |
Single-molecule biophysics: at the interface of biology, physics and chemistry AA Deniz, S Mukhopadhyay, EA Lemke Journal of the Royal Society Interface 5 (18), 15-45, 2008 | 390 | 2008 |
Reentrant phase transition drives dynamic substructure formation in ribonucleoprotein droplets PR Banerjee, AN Milin, MM Moosa, PL Onuchic, AA Deniz Angewandte Chemie 129 (38), 11512-11517, 2017 | 362 | 2017 |
Modulation of allostery by protein intrinsic disorder ACM Ferreon, JC Ferreon, PE Wright, AA Deniz Nature 498 (7454), 390-394, 2013 | 355 | 2013 |
A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures S Mukhopadhyay, R Krishnan, EA Lemke, S Lindquist, AA Deniz Proceedings of the National Academy of Sciences 104 (8), 2649-2654, 2007 | 354 | 2007 |
Self-interaction of NPM1 modulates multiple mechanisms of liquid–liquid phase separation DM Mitrea, JA Cika, CB Stanley, A Nourse, PL Onuchic, PR Banerjee, ... Nature communications 9 (1), 842, 2018 | 331 | 2018 |
Ratiometric single-molecule studies of freely diffusing biomolecules AA Deniz, TA Laurence, M Dahan, DS Chemla, PG Schultz, S Weiss Annual review of physical chemistry 52 (1), 233-253, 2001 | 265 | 2001 |
A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer EM Brustad, EA Lemke, PG Schultz, AA Deniz Journal of the American Chemical Society 130 (52), 17664-17665, 2008 | 236 | 2008 |
Ratiometric measurement and identification of single diffusing molecules M Dahan, AA Deniz, T Ha, DS Chemla, PG Schultz, S Weiss Chemical Physics 247 (1), 85-106, 1999 | 196 | 1999 |
FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices E Lerner, A Barth, J Hendrix, B Ambrose, V Birkedal, SC Blanchard, ... Elife 10, e60416, 2021 | 194 | 2021 |
Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer JR Grunwell, JL Glass, TD Lacoste, AA Deniz, DS Chemla, PG Schultz Journal of the American Chemical Society 123 (18), 4295-4303, 2001 | 173 | 2001 |
Unnatural amino acid mutagenesis of green fluorescent protein L Wang, J Xie, AA Deniz, PG Schultz The Journal of organic chemistry 68 (1), 174-176, 2003 | 157 | 2003 |
Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing Y Gambin, V VanDelinder, ACM Ferreon, EA Lemke, A Groisman, ... Nature methods 8 (3), 239-241, 2011 | 149 | 2011 |
Conserved features of intermediates in amyloid assembly determine their benign or toxic states R Krishnan, JL Goodman, S Mukhopadhyay, CD Pacheco, EA Lemke, ... Proceedings of the National Academy of Sciences 109 (28), 11172-11177, 2012 | 138 | 2012 |
Three‐color single‐molecule fluorescence resonance energy transfer JP Clamme, AA Deniz ChemPhysChem 6 (1), 74-77, 2005 | 135 | 2005 |
Single-molecule fluorescence studies of intrinsically disordered proteins ACM Ferreon, CR Moran, Y Gambin, AA Deniz Methods in enzymology 472, 179-204, 2010 | 133 | 2010 |