Neocentromeres: new insights into centromere structure, disease development, and karyotype evolution OJ Marshall, AC Chueh, LH Wong, KHA Choo The American Journal of Human Genetics 82 (2), 261-282, 2008 | 410 | 2008 |
LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin AC Chueh, EL Northrop, KH Brettingham-Moore, KHA Choo, LH Wong PLoS Genetics 5 (1), e1000354, 2009 | 188 | 2009 |
Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction AJ Wilson, AC Chueh, L Tögel, GA Corner, N Ahmed, S Goel, DS Byun, ... Cancer research 70 (2), 609-620, 2010 | 122 | 2010 |
Dual targeting of bromodomain and extraterminal domain proteins, and WNT or MAPK signaling, inhibits c-MYC expression and proliferation of colorectal cancer cells L Tögel, R Nightingale, AC Chueh, A Jayachandran, H Tran, T Phesse, ... Molecular cancer therapeutics 15 (6), 1217-1226, 2016 | 98 | 2016 |
Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere AC Chueh, LH Wong, N Wong, KHA Choo Human molecular genetics 14 (1), 85-93, 2005 | 84 | 2005 |
Mechanisms of histone deacetylase inhibitor-regulated gene expression in cancer cells AC Chueh, JWT Tse, L Tögel, JM Mariadason Antioxidants & redox signaling 23 (1), 66-84, 2015 | 80 | 2015 |
The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer … J Shin, A Carr, GA Corner, L Tögel, M Dávaos-Salas, H Tran, AC Chueh, ... Journal of Biological Chemistry 289 (36), 25306-25316, 2014 | 61 | 2014 |
FOXP3 over-expression inhibits melanoma tumorigenesis via effects on proliferation and apoptosis. BS Tan, M Anaka, S Deb, C Freyer, LM Ebert, AC Chueh, S Al-Obaidi, ... Oncotarget 5 (1), 264, 2014 | 60 | 2014 |
ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types AC Chüeh, JWT Tse, M Dickinson, P Ioannidis, L Jenkins, L Togel, ... Clinical Cancer Research 23 (18), 5573-5584, 2017 | 56 | 2017 |
BAC‐based PCR fragment microarray: High‐resolution detection of chromosomal deletion and duplication breakpoints H Ren, W Francis, A Boys, AC Chueh, N Wong, P La, LH Wong, J Ryan, ... Human mutation 25 (5), 476-482, 2005 | 52 | 2005 |
Transketolase-like 1 ectopic expression is associated with DNA hypomethylation and induces the Warburg effect in melanoma cells A Jayachandran, PH Lo, AC Chueh, P Prithviraj, R Molania, ... BMC cancer 16, 1-15, 2016 | 43 | 2016 |
A beacon of hope in stroke therapy—Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies A Hoque, MI Hossain, SS Ameen, CS Ang, N Williamson, DCH Ng, ... Pharmacology & Therapeutics 160, 159-179, 2016 | 37 | 2016 |
PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity O Gilan, J Diesch, M Amalia, K Jastrzebski, AC Chueh, NM Verrills, ... Oncogene 34 (10), 1333-1339, 2015 | 28 | 2015 |
Molecular Imaging of Death Receptor 5 Occupancy and Saturation Kinetics In Vivo by Humanized Monoclonal Antibody CS-1008 IJG Burvenich, FT Lee, GA Cartwright, GJ O'Keefe, D Makris, D Cao, ... Clinical Cancer Research 19 (21), 5984-5993, 2013 | 19 | 2013 |
Promoter hypomethylation of NY-ESO-1, association with clinicopathological features and PD-L1 expression in non-small cell lung cancer AC Chüeh, MS Liew, PA Russell, M Walkiewicz, A Jayachandran, ... Oncotarget 8 (43), 74036, 2017 | 17 | 2017 |
DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis L Tögel, R Nightingale, R Wu, AC Chüeh, S Al-Obaidi, I Luk, ... Scientific reports 8 (1), 1767, 2018 | 15 | 2018 |
CSK-Homologous Kinase HC Cheng, G Advani, MI Hossain, NL Ng, YC Lim, AC Chüeh, ... Encyclopedia of Signaling Molecules (Second Edition), 1215-1230, 2018 | 15 | 2018 |
CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation AC Chüeh, G Advani, M Foroutan, J Smith, N Ng, H Nandurkar, DS Lio, ... Oncogene 40 (17), 3015-3029, 2021 | 13 | 2021 |
Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine G Advani, YC Lim, B Catimel, DSS Lio, NLY Ng, AC Chüeh, M Tran, ... Cell Communication and Signaling 15, 1-22, 2017 | 12 | 2017 |
Proteomics‐based interrogation of the kinome and its implications for precision oncology TCC Lim Kam Sian, AC Chüeh, RJ Daly Proteomics 21 (17-18), 2000161, 2021 | 11 | 2021 |