| Molecular basis for the N-terminal bromodomain-and-extra-terminal-family selectivity of a dual kinase–bromodomain inhibitor A Divakaran, SK Talluri, AM Ayoub, NK Mishra, H Cui, JC Widen, ... Journal of Medicinal Chemistry 61 (20), 9316-9334, 2018 | 73 | 2018 |
| SAR by (protein-observed) 19F NMR A Divakaran, SE Kirberger, WCK Pomerantz Accounts of Chemical Research 52 (12), 3407-3418, 2019 | 51 | 2019 |
| Selective N‐Terminal BET Bromodomain Inhibitors by Targeting Non‐Conserved Residues and Structured Water Displacement H Cui, A Divakaran, AK Pandey, JA Johnson, H Zahid, ZJ Hoell, ... Angewandte Chemie International Edition 60 (3), 1220-1226, 2021 | 32 | 2021 |
| Wide dynamic range sensing with single quantum dot biosensors SR Opperwall, A Divakaran, EG Porter, JA Christians, AJ DenHartigh, ... ACS Nano 6 (9), 8078-8086, 2012 | 32 | 2012 |
| Systematically mitigating the p38α activity of triazole-based BET inhibitors AS Carlson, H Cui, A Divakaran, JA Johnson, RM Brunner, ... ACS Medicinal Chemistry Letters 10 (9), 1296-1301, 2019 | 31 | 2019 |
| 4-methyl-1, 2, 3-triazoles as N-acetyl-lysine mimics afford potent BET bromodomain inhibitors with improved selectivity H Cui, AS Carlson, MA Schleiff, A Divakaran, JA Johnson, CR Buchholz, ... Journal of Medicinal Chemistry 64 (14), 10497-10511, 2021 | 26 | 2021 |
| A structure-based design approach for generating high affinity BRD4 D1-selective chemical probes H Cui, A Divakaran, ZJ Hoell, MO Ellingson, CR Scholtz, H Zahid, ... Journal of Medicinal Chemistry 65 (3), 2342-2360, 2022 | 19 | 2022 |
| Identifying proteins that can form tyrosine-cysteine crosslinks RJ Martinie, PI Godakumbura, EG Porter, A Divakaran, BJ Burkhart, ... Metallomics 4 (10), 1037-1042, 2012 | 19 | 2012 |
| Recent progress and structural analyses of domain‐selective BET inhibitors A Divakaran, DA Harki, WCK Pomerantz Medicinal Research Reviews 43 (4), 972-1018, 2023 | 15 | 2023 |
| Exploiting the cullin E3 ligase adaptor protein SKP1 for targeted protein degradation SH Hong, A Divakaran, A Osa, OW Huang, IE Wertz, DK Nomura ACS Chemical Biology 19 (2), 442-450, 2024 | 9 | 2024 |
| Quantifying the selectivity of protein–protein and small molecule interactions with fluorinated tandem bromodomain reader proteins P Kalra, L McGraw, JR Kimbrough, AK Pandey, J Solberg, H Cui, ... ACS Chemical Biology 15 (11), 3038-3049, 2020 | 9 | 2020 |
| Development of an N-terminal BRD4 bromodomain-targeted degrader A Divakaran, CR Scholtz, H Zahid, W Lin, EC Griffith, RE Lee, T Chen, ... ACS Medicinal Chemistry Letters 13 (10), 1621-1627, 2022 | 5 | 2022 |
| Potent and selective N-terminal BRD4 bromodomain inhibitors by targeting non-conserved residues and structured water displacement H Cui, A Divakaran, AK Pandey, JA Johnson, H Aihara, DA Harki | 2 | 2020 |
| Therapeutic compounds and methods of use thereof JJ Topczewski, WCK Pomerantz, AS Carlson, H Cui, A Divakaran US Patent App. 18/639,608, 2024 | | 2024 |
| Therapeutic compounds and methods of use thereof JJ Topczewski, WCK Pomerantz, AS Carlson, H Cui, A Divakaran US Patent 11,987,572, 2024 | | 2024 |
| Selective brd4-degrader molecules H Cui, A Divakaran, DA Harki, WCK Pomerantz US Patent App. 18/228,422, 2024 | | 2024 |
| 6 Appendix A: Additional applications of AlphaScreen assay H Cui, A Divakaran, AK Pandey, JA Johnson, H Zahid, ZJ Hoell, ... Development of Small-Molecule Inhibitors and Biophysical Tools to Study the …, 2022 | | 2022 |
| Development and Cellular Evaluation of Selective N-Terminal BET Bromodomain Inhibitors A Divakaran | | 2021 |
| Selective bromodomain inhibition of BRD4-D1 using trisubstituted-imidazoles and triazoles A Divakaran, H Cui, S Henry, A Carlson ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
| Dual kinase-bromodomain inhibition of Brd4 and p38a using trisubstituted-imidazoles A Divakaran, S Talluri, A Ayoub, N Mishra, J Widen, JY Zhu, N Berndt, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
