Strategies to target ADAM17 in disease: from its discovery to the iRhom revolution M Calligaris, D Cuffaro, S Bonelli, DP Spanò, A Rossello, E Nuti, ... Molecules 26 (4), 944, 2021 | 72 | 2021 |
Sugar‐Based Arylsulfonamide Carboxylates as Selective and Water‐Soluble Matrix Metalloproteinase‐12 Inhibitors E Nuti, D Cuffaro, F D'Andrea, L Rosalia, L Tepshi, M Fabbi, G Carbotti, ... ChemMedChem 11 (15), 1626-1637, 2016 | 41 | 2016 |
Development of thioaryl-based matrix metalloproteinase-12 inhibitors with alternative zinc-binding groups: Synthesis, potentiometric, NMR, and crystallographic studies E Nuti, D Cuffaro, E Bernardini, C Camodeca, L Panelli, S Chaves, ... Journal of Medicinal Chemistry 61 (10), 4421-4435, 2018 | 39 | 2018 |
An overview of carbohydrate-based carbonic anhydrase inhibitors D Cuffaro, E Nuti, A Rossello Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1906-1922, 2020 | 32 | 2020 |
ADAM metalloproteinases as potential drug targets C Camodeca, D Cuffaro, E Nuti, A Rossello Current Medicinal Chemistry 26 (15), 2661-2689, 2019 | 25 | 2019 |
The metalloproteinase ADAM10 requires its activity to sustain surface expression A Seifert, S Düsterhöft, J Wozniak, CZ Koo, MG Tomlinson, E Nuti, ... Cellular and Molecular Life Sciences 78, 715-732, 2021 | 24 | 2021 |
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide S Santamaria, D Cuffaro, E Nuti, L Ciccone, T Tuccinardi, F Liva, ... Scientific reports 11 (1), 949, 2021 | 16 | 2021 |
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates D Cuffaro, C Camodeca, F D'Andrea, E Piragine, L Testai, V Calderone, ... Bioorganic & Medicinal Chemistry 26 (22), 5804-5815, 2018 | 16 | 2018 |
Bifunctional inhibitors as a new tool to reduce cancer cell invasion by impairing MMP-9 homodimerization E Nuti, L Rosalia, D Cuffaro, C Camodeca, C Giacomelli, E Da Pozzo, ... ACS Medicinal Chemistry Letters 8 (3), 293-298, 2017 | 16 | 2017 |
Bivalent inhibitor with selectivity for trimeric MMP-9 amplifies neutrophil chemotaxis and enables functional studies on MMP-9 proteoforms E Nuti, A Rossello, D Cuffaro, C Camodeca, J Van Bael, D van der Maat, ... Cells 9 (7), 1634, 2020 | 15 | 2020 |
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators A Nocentini, D Cuffaro, L Ciccone, E Orlandini, S Nencetti, E Nuti, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 48-57, 2021 | 12 | 2021 |
Identification of histone deacetylase inhibitors with (arylidene) aminoxy scaffold active in uveal melanoma cell lines S Nencetti, D Cuffaro, E Nuti, L Ciccone, A Rossello, M Fabbi, F Ballante, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 34-47, 2021 | 12 | 2021 |
Content variations in oleocanthalic acid and other phenolic compounds in extra-virgin olive oil during storage J Esposito Salsano, M Digiacomo, D Cuffaro, S Bertini, M Macchia Foods 11 (9), 1354, 2022 | 11 | 2022 |
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP) D Cuffaro, E Nuti, V Gifford, N Ito, C Camodeca, T Tuccinardi, S Nencetti, ... Bioorganic & Medicinal Chemistry 27 (1), 196-207, 2019 | 11 | 2019 |
Enhanced nutraceutical properties of extra virgin olive oil extract by olive leaf enrichment D Cuffaro, S Bertini, M Macchia, M Digiacomo Nutrients 15 (5), 1073, 2023 | 10 | 2023 |
Targeting aggrecanases for osteoarthritis therapy: from zinc chelation to exosite inhibition D Cuffaro, L Ciccone, A Rossello, E Nuti, S Santamaria Journal of medicinal chemistry 65 (20), 13505-13532, 2022 | 10 | 2022 |
Inhibitors of ADAM10 reduce Hodgkin lymphoma cell growth in 3D microenvironments and enhance brentuximab-vedotin effect R Pece, S Tavella, D Costa, S Varesano, C Camodeca, D Cuffaro, E Nuti, ... haematologica 107 (4), 909, 2022 | 7 | 2022 |
Identification of broad-spectrum MMP inhibitors by virtual screening A Gimeno, D Cuffaro, E Nuti, MJ Ojeda-Montes, R Beltrán-Debón, ... Molecules 26 (15), 4553, 2021 | 6 | 2021 |
Insights into the antioxidant/antiradical effects and in vitro intestinal permeation of Oleocanthal and its metabolites Tyrosol and Oleocanthalic acid D Cuffaro, D Pinto, AM Silva, A Bertolini, S Bertini, A Saba, M Macchia, ... Molecules 28 (13), 5150, 2023 | 5 | 2023 |
Ionic liquid-promoted green synthesis of biologically relevant diaryl thioethers D Cuffaro, F D’Andrea, A Mezzetta, L Guazzelli, C Chiappe, E Nuti, ... Green Chemistry Letters and Reviews 13 (4), 295-302, 2020 | 5 | 2020 |