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DORETTA CUFFARO
DORETTA CUFFARO
Junior researcher at Department of Pharmacy, University of pisa
在 unipi.it 的电子邮件经过验证
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引用次数
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年份
Strategies to target ADAM17 in disease: from its discovery to the iRhom revolution
M Calligaris, D Cuffaro, S Bonelli, DP Spanò, A Rossello, E Nuti, ...
Molecules 26 (4), 944, 2021
722021
Sugar‐Based Arylsulfonamide Carboxylates as Selective and Water‐Soluble Matrix Metalloproteinase‐12 Inhibitors
E Nuti, D Cuffaro, F D'Andrea, L Rosalia, L Tepshi, M Fabbi, G Carbotti, ...
ChemMedChem 11 (15), 1626-1637, 2016
412016
Development of thioaryl-based matrix metalloproteinase-12 inhibitors with alternative zinc-binding groups: Synthesis, potentiometric, NMR, and crystallographic studies
E Nuti, D Cuffaro, E Bernardini, C Camodeca, L Panelli, S Chaves, ...
Journal of Medicinal Chemistry 61 (10), 4421-4435, 2018
392018
An overview of carbohydrate-based carbonic anhydrase inhibitors
D Cuffaro, E Nuti, A Rossello
Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1906-1922, 2020
322020
ADAM metalloproteinases as potential drug targets
C Camodeca, D Cuffaro, E Nuti, A Rossello
Current Medicinal Chemistry 26 (15), 2661-2689, 2019
252019
The metalloproteinase ADAM10 requires its activity to sustain surface expression
A Seifert, S Düsterhöft, J Wozniak, CZ Koo, MG Tomlinson, E Nuti, ...
Cellular and Molecular Life Sciences 78, 715-732, 2021
242021
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide
S Santamaria, D Cuffaro, E Nuti, L Ciccone, T Tuccinardi, F Liva, ...
Scientific reports 11 (1), 949, 2021
162021
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates
D Cuffaro, C Camodeca, F D'Andrea, E Piragine, L Testai, V Calderone, ...
Bioorganic & Medicinal Chemistry 26 (22), 5804-5815, 2018
162018
Bifunctional inhibitors as a new tool to reduce cancer cell invasion by impairing MMP-9 homodimerization
E Nuti, L Rosalia, D Cuffaro, C Camodeca, C Giacomelli, E Da Pozzo, ...
ACS Medicinal Chemistry Letters 8 (3), 293-298, 2017
162017
Bivalent inhibitor with selectivity for trimeric MMP-9 amplifies neutrophil chemotaxis and enables functional studies on MMP-9 proteoforms
E Nuti, A Rossello, D Cuffaro, C Camodeca, J Van Bael, D van der Maat, ...
Cells 9 (7), 1634, 2020
152020
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators
A Nocentini, D Cuffaro, L Ciccone, E Orlandini, S Nencetti, E Nuti, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 48-57, 2021
122021
Identification of histone deacetylase inhibitors with (arylidene) aminoxy scaffold active in uveal melanoma cell lines
S Nencetti, D Cuffaro, E Nuti, L Ciccone, A Rossello, M Fabbi, F Ballante, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 34-47, 2021
122021
Content variations in oleocanthalic acid and other phenolic compounds in extra-virgin olive oil during storage
J Esposito Salsano, M Digiacomo, D Cuffaro, S Bertini, M Macchia
Foods 11 (9), 1354, 2022
112022
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP)
D Cuffaro, E Nuti, V Gifford, N Ito, C Camodeca, T Tuccinardi, S Nencetti, ...
Bioorganic & Medicinal Chemistry 27 (1), 196-207, 2019
112019
Enhanced nutraceutical properties of extra virgin olive oil extract by olive leaf enrichment
D Cuffaro, S Bertini, M Macchia, M Digiacomo
Nutrients 15 (5), 1073, 2023
102023
Targeting aggrecanases for osteoarthritis therapy: from zinc chelation to exosite inhibition
D Cuffaro, L Ciccone, A Rossello, E Nuti, S Santamaria
Journal of medicinal chemistry 65 (20), 13505-13532, 2022
102022
Inhibitors of ADAM10 reduce Hodgkin lymphoma cell growth in 3D microenvironments and enhance brentuximab-vedotin effect
R Pece, S Tavella, D Costa, S Varesano, C Camodeca, D Cuffaro, E Nuti, ...
haematologica 107 (4), 909, 2022
72022
Identification of broad-spectrum MMP inhibitors by virtual screening
A Gimeno, D Cuffaro, E Nuti, MJ Ojeda-Montes, R Beltrán-Debón, ...
Molecules 26 (15), 4553, 2021
62021
Insights into the antioxidant/antiradical effects and in vitro intestinal permeation of Oleocanthal and its metabolites Tyrosol and Oleocanthalic acid
D Cuffaro, D Pinto, AM Silva, A Bertolini, S Bertini, A Saba, M Macchia, ...
Molecules 28 (13), 5150, 2023
52023
Ionic liquid-promoted green synthesis of biologically relevant diaryl thioethers
D Cuffaro, F D’Andrea, A Mezzetta, L Guazzelli, C Chiappe, E Nuti, ...
Green Chemistry Letters and Reviews 13 (4), 295-302, 2020
52020
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