Crystal structure of opsin in its G-protein-interacting conformation P Scheerer, JH Park, PW Hildebrand, YJ Kim, N Krauß, HW Choe, ... Nature 455 (7212), 497-502, 2008 | 1353 | 2008 |
NGL Viewer: a web application for molecular visualization AS Rose, PW Hildebrand Nucleic acids research 43 (W1), W576-W579, 2015 | 488 | 2015 |
AG protein-coupled receptor at work: the rhodopsin model KP Hofmann, P Scheerer, PW Hildebrand, HW Choe, JH Park, M Heck, ... Trends in biochemical sciences 34 (11), 540-552, 2009 | 446 | 2009 |
Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites AH Ratje, J Loerke, A Mikolajka, M Brünner, PW Hildebrand, AL Starosta, ... Nature 468 (7324), 713-716, 2010 | 391 | 2010 |
Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production A Brehm, Y Liu, A Sheikh, B Marrero, E Omoyinmi, Q Zhou, ... The Journal of clinical investigation 125 (11), 4196-4211, 2015 | 295 | 2015 |
Crystal structure of a common GPCR-binding interface for G protein and arrestin M Szczepek, F Beyrière, KP Hofmann, M Elgeti, R Kazmin, A Rose, ... Nature communications 5 (1), 4801, 2014 | 189 | 2014 |
Bringing molecular dynamics simulation data into view PW Hildebrand, AS Rose, JKS Tiemann Trends in Biochemical Sciences 44 (11), 902-913, 2019 | 167 | 2019 |
Membrane cholesterol access into a G-protein-coupled receptor R Guixà-González, JL Albasanz, I Rodriguez-Espigares, M Pastor, F Sanz, ... Nature communications 8 (1), 14505, 2017 | 152 | 2017 |
Structural insights into the process of GPCR-G protein complex formation X Liu, X Xu, D Hilger, P Aschauer, JKS Tiemann, Y Du, H Liu, K Hirata, ... Cell 177 (5), 1243-1251. e12, 2019 | 146 | 2019 |
Role of amyloid-β glycine 33 in oligomerization, toxicity, and neuronal plasticity A Harmeier, C Wozny, BR Rost, LM Munter, H Hua, O Georgiev, ... Journal of Neuroscience 29 (23), 7582-7590, 2009 | 136 | 2009 |
Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement TV Budkevich, J Giesebrecht, E Behrmann, J Loerke, DJF Ramrath, ... Cell 158 (1), 121-131, 2014 | 134 | 2014 |
A ligand channel through the G protein coupled receptor opsin PW Hildebrand, P Scheerer, JH Park, HW Choe, R Piechnick, OP Ernst, ... PloS one 4 (2), e4382, 2009 | 132 | 2009 |
Amyloid beta 42 peptide (Aβ42)-lowering compounds directly bind to Aβ and interfere with amyloid precursor protein (APP) transmembrane dimerization L Richter, LM Munter, J Ness, PW Hildebrand, M Dasari, S Unterreitmeier, ... Proceedings of the National Academy of Sciences 107 (33), 14597-14602, 2010 | 124 | 2010 |
Position of transmembrane helix 6 determines receptor G protein coupling specificity AS Rose, M Elgeti, U Zachariae, H Grubmüller, KP Hofmann, ... Journal of the American Chemical Society 136 (32), 11244-11247, 2014 | 117 | 2014 |
GPCRmd uncovers the dynamics of the 3D-GPCRome I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ... Nature Methods 17 (8), 777-787, 2020 | 114 | 2020 |
SuperLooper—a prediction server for the modeling of loops in globular and membrane proteins PW Hildebrand, A Goede, RA Bauer, B Gruening, J Ismer, E Michalsky, ... Nucleic acids research 37 (suppl_2), W571-W574, 2009 | 109 | 2009 |
Voronoia: analyzing packing in protein structures K Rother, PW Hildebrand, A Goede, B Gruening, R Preissner Nucleic acids research 37 (suppl_1), D393-D395, 2009 | 106 | 2009 |
Structural features of transmembrane helices PW Hildebrand, R Preissner, C Frömmel FEBS letters 559 (1-3), 145-151, 2004 | 98 | 2004 |
Novel APP/Aβ mutation K16N produces highly toxic heteromeric Aβ oligomers D Kaden, A Harmeier, C Weise, LM Munter, V Althoff, BR Rost, ... EMBO molecular medicine 4 (7), 647-659, 2012 | 96 | 2012 |
Molecular architecture of the ribosome‐bound Hepatitis C Virus internal ribosomal entry site RNA H Yamamoto, M Collier, J Loerke, J Ismer, A Schmidt, T Hilal, T Sprink, ... The EMBO journal 34 (24), 3042-3058, 2015 | 92 | 2015 |