| Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy CM Overall, O Kleifeld Nature Reviews Cancer 6 (3), 227-239, 2006 | 1449 | 2006 |
| Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products O Kleifeld, A Doucet, U auf dem Keller, A Prudova, O Schilling, ... Nature biotechnology 28 (3), 281-288, 2010 | 576 | 2010 |
| Towards third generation matrix metalloproteinase inhibitors for cancer therapy CM Overall, O Kleifeld British journal of cancer 94 (7), 941-946, 2006 | 428 | 2006 |
| Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates O Kleifeld, A Doucet, A Prudova, M Gioia, JN Kizhakkedathu, CM Overall Nature protocols 6 (10), 1578-1611, 2011 | 300 | 2011 |
| auf dem Keller U, Gioia M, Kizhakkedathu JN, Overall CM (2011) Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of … O Kleifeld, A Doucet, A Prudova Nat. Protoc 6, 1578-1611, 0 | 198 | |
| Reversible 26S proteasome disassembly upon mitochondrial stress N Livnat-Levanon, E Kevei, O Kleifeld, D Krutauz, A Segref, T Rinaldi, ... Cell reports 7 (5), 1371-1380, 2014 | 187 | 2014 |
| auf dem Keller U, Prudova A, Schilling O, Kainthan RK, Starr AE, Foster LJ, Kizhakkedathu JN, Overall CM. 2010. Isotopic labeling of terminal amines in complex samples … O Kleifeld, A Doucet Nat Biotechnol 28 (3), 281-288, 2010 | 176 | 2010 |
| A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis I Ziv, Y Matiuhin, DS Kirkpatrick, Z Erpapazoglou, S Leon, ... Molecular & Cellular Proteomics 10 (5), 2011 | 166 | 2011 |
| LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification PF Huesgen, PF Lange, LD Rogers, N Solis, U Eckhard, O Kleifeld, ... Nature methods 12 (1), 55-58, 2015 | 161 | 2015 |
| The eIF3 interactome reveals the translasome, a supercomplex linking protein synthesis and degradation machineries Z Sha, LM Brill, R Cabrera, O Kleifeld, JS Scheliga, MH Glickman, ... Molecular cell 36 (1), 141-152, 2009 | 158 | 2009 |
| Conformational changes during pore formation by the perforin-related protein pleurotolysin N Lukoyanova, SC Kondos, I Farabella, RHP Law, CF Reboul, ... PLoS biology 13 (2), e1002049, 2015 | 145 | 2015 |
| Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis P Deo, SH Chow, ID Hay, O Kleifeld, A Costin, KD Elgass, JH Jiang, ... PLoS pathogens 14 (3), e1006945, 2018 | 141 | 2018 |
| Active site electronic structure and dynamics during metalloenzyme catalysis O Kleifeld, A Frenkel, JML Martin, I Sagi Nature structural biology 10 (2), 98-103, 2003 | 140 | 2003 |
| Granzyme B promotes cytotoxic lymphocyte transmigration via basement membrane remodeling MD Prakash, MA Munoz, R Jain, PL Tong, A Koskinen, M Regner, ... Immunity 41 (6), 960-972, 2014 | 131 | 2014 |
| Extraproteasomal Rpn10 restricts access of the polyubiquitin-binding protein Dsk2 to proteasome Y Matiuhin, DS Kirkpatrick, I Ziv, W Kim, A Dakshinamurthy, O Kleifeld, ... Molecular cell 32 (3), 415-425, 2008 | 121 | 2008 |
| Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia P Sulkshane, J Ram, A Thakur, N Reis, O Kleifeld, MH Glickman Redox biology 45, 102047, 2021 | 119 | 2021 |
| Phase speciation by extended x-ray absorption fine structure spectroscopy AI Frenkel, O Kleifeld, SR Wasserman, I Sagi The Journal of chemical physics 116 (21), 9449-9456, 2002 | 104 | 2002 |
| X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) bound to a highly selective mechanism-based inhibitor: Comparison with the latent and active forms of the … O Kleifeld, LP Kotra, DC Gervasi, S Brown, MM Bernardo, R Fridman, ... Journal of Biological Chemistry 276 (20), 17125-17131, 2001 | 104 | 2001 |
| The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag I Sahu, SM Mali, P Sulkshane, C Xu, A Rozenberg, R Morag, MP Sahoo, ... Nature communications 12 (1), 6173, 2021 | 102 | 2021 |
| N-terminomics TAILS identifies host cell substrates of poliovirus and coxsackievirus B3 3C proteinases that modulate virus infection JM Jagdeo, A Dufour, T Klein, N Solis, O Kleifeld, J Kizhakkedathu, H Luo, ... Journal of virology 92 (8), 10.1128/jvi. 02211-17, 2018 | 83 | 2018 |
