| Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin MOW Grimm, HS Grimm, AJ Pätzold, EG Zinser, R Halonen, M Duering, ... Nature cell biology 7 (11), 1118-1123, 2005 | 552 | 2005 |
| Mechanism of the cleavage specificity of Alzheimer’s disease γ-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor … SF Lichtenthaler, R Wang, H Grimm, SN Uljon, CL Masters, K Beyreuther Proceedings of the National Academy of Sciences 96 (6), 3053-3058, 1999 | 312 | 1999 |
| Docosahexaenoic acid reduces amyloid β production via multiple pleiotropic mechanisms MOW Grimm, J Kuchenbecker, S Grösgen, VK Burg, B Hundsdörfer, ... Journal of Biological Chemistry 286 (16), 14028-14039, 2011 | 253 | 2011 |
| Independent inhibition of Alzheimer disease β-and γ-secretase cleavage by lowered cholesterol levels MOW Grimm, HS Grimm, I Tomic, K Beyreuther, T Hartmann, C Bergmann Journal of Biological Chemistry 283 (17), 11302-11311, 2008 | 161 | 2008 |
| Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study VK Burg, HS Grimm, TL Rothhaar, S Grösgen, B Hundsdörfer, ... Journal of Neuroscience 33 (41), 16072-16087, 2013 | 151 | 2013 |
| From brain to food: Analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin–plasmalogens derivates in Alzheimer's disease human post mortem brains and … MOW Grimm, S Grösgen, M Riemenschneider, H Tanila, HS Grimm, ... Journal of Chromatography A 1218 (42), 7713-7722, 2011 | 137 | 2011 |
| Mean age of onset in familial Alzheimer's disease is determined by amyloid beta 42 M Duering, MOW Grimm, HS Grimm, J Schröder, T Hartmann Neurobiology of aging 26 (6), 785-788, 2005 | 136 | 2005 |
| Plasmalogen synthesis is regulated via alkyl‐dihydroxyacetonephosphate‐synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease MOW Grimm, J Kuchenbecker, TL Rothhaar, S Grösgen, B Hundsdörfer, ... Journal of neurochemistry 116 (5), 916-925, 2011 | 129 | 2011 |
| Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the β-amyloid peptide … V Echeverria, A Ducatenzeiler, E Dowd, J Jänne, SM Grant, M Szyf, ... Neuroscience 129 (3), 583-592, 2004 | 124 | 2004 |
| APP function and lipids: a bidirectional link MOW Grimm, J Mett, HS Grimm, T Hartmann Frontiers in molecular neuroscience 10, 63, 2017 | 103 | 2017 |
| The impact of cholesterol, DHA, and sphingolipids on Alzheimer’s disease MOW Grimm, VC Zimmer, J Lehmann, HS Grimm, T Hartmann BioMed research international 2013 (1), 814390, 2013 | 101 | 2013 |
| Amyloid beta as a regulator of lipid homeostasis MOW Grimm, HS Grimm, T Hartmann Trends in molecular medicine 13 (8), 337-344, 2007 | 100 | 2007 |
| Vitamin D and its analogues decrease amyloid-β (Aβ) formation and increase Aβ-degradation MOW Grimm, A Thiel, AA Lauer, J Winkler, J Lehmann, L Regner, C Nelke, ... International journal of molecular sciences 18 (12), 2764, 2017 | 97 | 2017 |
| The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain SF Lichtenthaler, D Beher, HS Grimm, R Wang, MS Shearman, ... Proceedings of the National Academy of Sciences 99 (3), 1365-1370, 2002 | 88 | 2002 |
| APP intracellular domain derived from amyloidogenic β-and γ-secretase cleavage regulates neprilysin expression MOW Grimm, J Mett, CP Stahlmann, S Grösgen, VJ Haupenthal, T Blümel, ... Frontiers in aging neuroscience 7, 77, 2015 | 85 | 2015 |
| Plasmalogens Inhibit APP Processing by Directly Affecting γ‐Secretase Activity in Alzheimer’s Disease TL Rothhaar, S Grösgen, VJ Haupenthal, VK Burg, B Hundsdörfer, J Mett, ... The Scientific World Journal 2012 (1), 141240, 2012 | 83 | 2012 |
| Impact of vitamin D on amyloid precursor protein processing and amyloid-β peptide degradation in Alzheimer's disease MOW Grimm, J Lehmann, J Mett, VC Zimmer, S Grösgen, CP Stahlmann, ... Neurodegenerative diseases 13 (2-3), 75-81, 2014 | 77 | 2014 |
| Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism MOW Grimm, EG Zinser, S Grösgen, B Hundsdörfer, TL Rothhaar, ... PloS one 7 (3), e34095, 2012 | 75 | 2012 |
| Intracellular APP domain regulates serine-palmitoyl-CoA transferase expression and is affected in Alzheimer's disease MOW Grimm, S Grösgen, TL Rothhaar, VK Burg, B Hundsdörfer, ... International journal of Alzheimer's disease 2011, 2011 | 72 | 2011 |
| Oxidized docosahexaenoic acid species and lipid peroxidation products increase amyloidogenic amyloid precursor protein processing MOW Grimm, VJ Haupenthal, J Mett, CP Stahlmann, T Blümel, ... Neurodegenerative diseases 16 (1-2), 44-54, 2016 | 62 | 2016 |
