Fluorescence-activated droplet sorting for single-cell directed evolution D Vallejo, A Nikoomanzar, BM Paegel, JC Chaput ACS synthetic biology 8 (6), 1430-1440, 2019 | 111 | 2019 |
Evolution of a general RNA-cleaving FANA enzyme Y Wang, AK Ngor, A Nikoomanzar, JC Chaput Nature Communications 9 (1), 5067, 2018 | 75 | 2018 |
Engineering polymerases for applications in synthetic biology A Nikoomanzar, N Chim, EJ Yik, JC Chaput Quarterly reviews of biophysics 53, e8, 2020 | 61 | 2020 |
Structural basis for TNA synthesis by an engineered TNA polymerase N Chim, C Shi, SP Sau, A Nikoomanzar, JC Chaput Nature Communications 8 (1), 1810, 2017 | 51 | 2017 |
Elucidating the determinants of polymerase specificity by microfluidic-based deep mutational scanning A Nikoomanzar, D Vallejo, JC Chaput ACS Synthetic Biology 8 (6), 1421-1429, 2019 | 38 | 2019 |
Programmed allelic mutagenesis of a DNA polymerase with single amino acid resolution A Nikoomanzar, D Vallejo, EJ Yik, JC Chaput ACS Synthetic Biology 9 (7), 1873-1881, 2020 | 35 | 2020 |
Engineered polymerases with altered substrate specificity: Expression and purification A Nikoomanzar, MR Dunn, JC Chaput Current Protocols in Nucleic Acid Chemistry 69 (1), 4.75. 1-4.75. 20, 2017 | 24 | 2017 |
Evaluating the rate and substrate specificity of laboratory evolved XNA polymerases A Nikoomanzar, MR Dunn, JC Chaput Analytical chemistry 89 (23), 12622-12625, 2017 | 20 | 2017 |
DNA sequencing using polymerase substrate-binding kinetics MJR Previte, C Zhou, M Kellinger, R Pantoja, CY Chen, J Shi, BB Wang, ... Nature communications 6 (1), 5936, 2015 | 17 | 2015 |
ACS Synth D Vallejo, A Nikoomanzar, BM Paegel, JC Chaput Biol 8, 1430, 2019 | 8 | 2019 |
Directed evolution of custom polymerases using droplet microfluidics D Vallejo, A Nikoomanzar, JC Chaput Methods in Enzymology 644, 227-253, 2020 | 7 | 2020 |
Strand displacing amplification enzymes N Souad, EN Glezer, BK Kutche, A Nikoomanzar, A Sevy, C Newman, ... US Patent App. 18/145,007, 2023 | | 2023 |
Strand displacing sequencing enzymes N Souad, EN Glezer, BK Kutche, A Nikoomanzar, A Sevy, C Newman, ... US Patent App. 18/069,990, 2023 | | 2023 |
Engineering DNA Polymerases to Synthesize Unnatural Genetic Polymers for Applications in Synthetic Biology A Nikoomanzar University of California, Irvine, 2020 | | 2020 |
Hybrid nanopores for highly parallelized nanopore platforms J Bai, N Sam-Soon, A Nikoomanzar, CY Chen, L Qiang, B Baas, ... NHGRI Advanced DNA Sequencing Technology Development Meeting, San Diego, CA …, 2015 | | 2015 |