From Pd(OAc)2 to Chiral Catalysts: The Discovery and Development of Bifunctional Mono-N-Protected Amino Acid Ligands for Diverse C–H Functionalization … Q Shao, K Wu, Z Zhuang, S Qian, JQ Yu Accounts of chemical research 53 (4), 833-851, 2020 | 325 | 2020 |
Ligand-accelerated enantioselective methylene C (sp3)–H bond activation G Chen, W Gong, Z Zhuang, MS Andrä, YQ Chen, X Hong, YF Yang, T Liu, ... Science 353 (6303), 1023-1027, 2016 | 315 | 2016 |
Ligand‐enabled β‐C–H arylation of α‐amino acids without installing exogenous directing groups G Chen, Z Zhuang, GC Li, TG Saint‐Denis, Y Hsiao, CL Joe, JQ Yu Angewandte Chemie 129 (6), 1528-1531, 2017 | 133 | 2017 |
Lactonization as a general route to β-C(sp3)–H functionalization Z Zhuang, JQ Yu Nature 577 (7792), 656-659, 2020 | 118 | 2020 |
Ligand-Enabled β-C(sp3)–H Olefination of Free Carboxylic Acids Z Zhuang, CB Yu, G Chen, QF Wu, Y Hsiao, CL Joe, JX Qiao, MA Poss, ... Journal of the American Chemical Society 140 (32), 10363-10367, 2018 | 113 | 2018 |
Pd(II)-Catalyzed Enantioselective γ-C(sp3)–H Functionalizations of Free Cyclopropylmethylamines Z Zhuang, JQ Yu Journal of the American Chemical Society 142 (28), 12015-12019, 2020 | 95 | 2020 |
Ligand-controlled divergent dehydrogenative reactions of carboxylic acids via C–H activation Z Wang, L Hu, N Chekshin, Z Zhuang, S Qian, JX Qiao, JQ Yu Science 374 (6572), 1281-1285, 2021 | 86 | 2021 |
Ligand-Enabled Monoselective β-C(sp3)–H Acyloxylation of Free Carboxylic Acids Using a Practical Oxidant Z Zhuang, AN Herron, Z Fan, JQ Yu Journal of the American Chemical Society 142 (14), 6769-6776, 2020 | 79 | 2020 |
Palladium-Catalyzed Enantioselective β-C(sp3)–H Activation Reactions of Aliphatic Acids: A Retrosynthetic Surrogate for Enolate Alkylation and Conjugate Addition EL Lucas, NYS Lam, Z Zhuang, HSS Chan, DA Strassfeld, JQ Yu Accounts of chemical research 55 (4), 537-550, 2022 | 76 | 2022 |
Merging C (sp 3)–H activation with DNA-encoding Z Fan, S Zhao, T Liu, PX Shen, ZN Cui, Z Zhuang, Q Shao, JS Chen, ... Chemical Science 11 (45), 12282-12288, 2020 | 65 | 2020 |
Ligand‐Enabled β‐Methylene C(sp3)−H Arylation of Masked Aliphatic Alcohols G Xia, Z Zhuang, LY Liu, SL Schreiber, B Melillo, JQ Yu Angewandte Chemie International Edition 59 (20), 7783-7787, 2020 | 47 | 2020 |
Rational development of remote C− H functionalization of biphenyl: Experimental and computational studies Z Fan, KL Bay, X Chen, Z Zhuang, HS Park, KS Yeung, KN Houk, JQ Yu Angewandte Chemie 132 (12), 4800-4807, 2020 | 47 | 2020 |
Rapid construction of tetralin, chromane, and indane motifs via cyclative C–H/C–H coupling: four-step total synthesis of (±)-russujaponol F Z Zhuang, AN Herron, S Liu, JQ Yu Journal of the American Chemical Society 143 (2), 687-692, 2021 | 41 | 2021 |
One-step synthesis of β-alkylidene-γ-lactones via ligand-enabled β, γ-dehydrogenation of aliphatic acids T Sheng, Z Zhuang, Z Wang, L Hu, AN Herron, JX Qiao, JQ Yu Journal of the American Chemical Society 144 (28), 12924-12933, 2022 | 39 | 2022 |
Construction of Highly Functional Quaternary Carbon Stereocenters via an Organocatalytic Tandem Cyanation–Allylic Alkylation Reaction Z Zhuang, F Pan, JG Fu, JM Chen, WW Liao Organic Letters 13 (23), 6164-6167, 2011 | 36 | 2011 |
Asymmetric synthesis of functionalized dihydronaphthoquinones containing quaternary carbon centers via a metal-free catalytic intramolecular acylcyanation of activated alkenes Z Zhuang, ZP Hu, WW Liao Organic Letters 16 (12), 3380-3383, 2014 | 35 | 2014 |
Construction of highly functional α-amino nitriles via a novel multicomponent tandem organocatalytic reaction: a facile access to α-methylene γ-lactams F Pan, JM Chen, Z Zhuang, YZ Fang, SXA Zhang, WW Liao Organic & Biomolecular Chemistry 10 (11), 2214-2217, 2012 | 35 | 2012 |
Synthesis of Cyclic Anhydrides via Ligand‐Enabled C–H Carbonylation of Simple Aliphatic Acids Z Zhuang, AN Herron, JQ Yu Angewandte Chemie 133 (30), 16518-16523, 2021 | 33 | 2021 |
Ligand Enabled Pd(II)-Catalyzed γ-C(sp3)–H Lactamization of Native Amides S Liu, Z Zhuang, JX Qiao, KS Yeung, S Su, EC Cherney, Z Ruan, ... Journal of the American Chemical Society 143 (51), 21657-21666, 2021 | 30 | 2021 |
Lewis base promoted intramolecular acylcyanation of α-substituted activated alkenes: Construction of ketones bearing β-quaternary carbon centers Z Zhuang, JM Chen, F Pan, WW Liao Organic letters 14 (9), 2354-2357, 2012 | 20 | 2012 |