| ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes K Yoshimi, Y Kunihiro, T Kaneko, H Nagahora, B Voigt, T Mashimo Nature communications 7 (1), 10431, 2016 | 380 | 2016 |
| Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases T Mashimo, A Takizawa, B Voigt, K Yoshimi, H Hiai, T Kuramoto, ... PloS one 5 (1), e8870, 2010 | 303 | 2010 |
| Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform K Yoshimi, T Kaneko, B Voigt, T Mashimo Nature communications 5 (1), 4240, 2014 | 204 | 2014 |
| CRISPR-Cas3 induces broad and unidirectional genome editing in human cells H Morisaka, K Yoshimi, Y Okuzaki, P Gee, Y Kunihiro, E Sonpho, H Xu, ... Nature communications 10 (1), 5302, 2019 | 171 | 2019 |
| CLICK: one-step generation of conditional knockout mice Y Miyasaka, Y Uno, K Yoshimi, Y Kunihiro, T Yoshimura, T Tanaka, ... BMC genomics 19, 1-8, 2018 | 89 | 2018 |
| Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation CB Gurumurthy, AR O’brien, RM Quadros, J Adams, P Alcaide, S Ayabe, ... Genome biology 20 (1), 1-14, 2019 | 88 | 2019 |
| The utility of Apc-mutant rats in modeling human colon cancer AA Irving, K Yoshimi, ML Hart, T Parker, L Clipson, MR Ford, T Kuramoto, ... Disease models & mechanisms 7 (11), 1215-1225, 2014 | 88 | 2014 |
| Generation and characterization of severe combined immunodeficiency rats T Mashimo, A Takizawa, J Kobayashi, Y Kunihiro, K Yoshimi, S Ishida, ... Cell reports 2 (3), 685-694, 2012 | 81 | 2012 |
| Hierarchy in the home cage affects behaviour and gene expression in group-housed C57BL/6 male mice Y Horii, T Nagasawa, H Sakakibara, A Takahashi, A Tanave, ... Scientific reports 7 (1), 6991, 2017 | 70 | 2017 |
| Enhanced colitis‐associated colon carcinogenesis in a novel Apc mutant rat K Yoshimi, T Tanaka, A Takizawa, M Kato, M Hirabayashi, T Mashimo, ... Cancer science 100 (11), 2022-2027, 2009 | 57 | 2009 |
| Rapid and accurate detection of novel coronavirus SARS-CoV-2 using CRISPR-Cas3 K Yoshimi, K Takeshita, S Yamayoshi, S Shibumura, Y Yamauchi, ... MedRxiv, 2020.06. 02.20119875, 2020 | 43 | 2020 |
| Combi-CRISPR: combination of NHEJ and HDR provides efficient and precise plasmid-based knock-ins in mice and rats K Yoshimi, Y Oka, Y Miyasaka, Y Kotani, M Yasumura, Y Uno, K Hattori, ... Human Genetics 140, 277-287, 2021 | 40 | 2021 |
| CRISPR-Cas3-based diagnostics for SARS-CoV-2 and influenza virus K Yoshimi, K Takeshita, S Yamayoshi, S Shibumura, Y Yamauchi, ... Iscience 25 (2), 2022 | 38 | 2022 |
| Use of a chemically induced-colon carcinogenesis-prone Apc-mutant rat in a chemotherapeutic bioassay K Yoshimi, T Hashimoto, Y Niwa, K Hata, T Serikawa, T Tanaka, ... BMC cancer 12, 1-8, 2012 | 26 | 2012 |
| Next-generation prebiotic promotes selective growth of bifidobacteria, suppressing Clostridioides difficile R Hirano, M Sakanaka, K Yoshimi, N Sugimoto, S Eguchi, Y Yamauchi, ... Gut Microbes 13 (1), 1973835, 2021 | 24 | 2021 |
| Tumor suppressor APC protein is essential in mucosal repair from colonic inflammation through angiogenesis K Yoshimi, T Tanaka, T Serikawa, T Kuramoto The American Journal of Pathology 182 (4), 1263-1274, 2013 | 24 | 2013 |
| Dynamic mechanisms of CRISPR interference by Escherichia coli CRISPR-Cas3 K Yoshimi, K Takeshita, N Kodera, S Shibumura, Y Yamauchi, M Omatsu, ... Nature communications 13 (1), 4917, 2022 | 22 | 2022 |
| Utility of Apc-mutant rats with a colitis-associated colon carcinogenesis model for chemoprevention studies T Kochi, M Shimizu, Y Shirakami, K Yoshimi, T Kuramoto, T Tanaka, ... European Journal of Cancer Prevention 24 (3), 180-187, 2015 | 22 | 2015 |
| Tremor dominant Kyoto (Trdk) rats carry a missense mutation in the gene encoding the SK2 subunit of small-conductance Ca2+-activated K+ channel T Kuramoto, M Yokoe, N Kunisawa, K Ohashi, T Miyake, Y Higuchi, ... Brain research 1676, 38-45, 2017 | 19 | 2017 |
| Application of genome editing technologies in rats for human disease models K Yoshimi, T Mashimo Journal of human genetics 63 (2), 115-123, 2018 | 18 | 2018 |
