Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP‐induced receptor signaling and platelet aggregation JJJ Van Giezen, L Nilsson, P Berntsson, BM Wissing, F Giordanetto, ... Journal of thrombosis and haemostasis 7 (9), 1556-1565, 2009 | 350 | 2009 |
Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism S Nylander, EA Femia, M Scavone, P Berntsson, AK Asztély, K Nelander, ... Journal of Thrombosis and Haemostasis 11 (10), 1867-1876, 2013 | 190 | 2013 |
Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis JJJ Van Giezen, P Berntsson, H Zachrisson, JA Björkman Thrombosis research 124 (5), 565-571, 2009 | 105 | 2009 |
Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down‐regulating … W Knecht, J Willemse, H Stenhamre, M Andersson, P Berntsson, ... The FEBS journal 273 (4), 778-792, 2006 | 50 | 2006 |
Treatment of cells with the polyamine analog N1,N11‐diethylnorspermine retards S phase progression within one cell cycle K Alm, PSH Berntsson, DL Kramer, CW Porter, SM Oredsson European Journal of Biochemistry 267 (13), 4157-4164, 2000 | 49 | 2000 |
Comprendo: Focus and approach U Schulte-Oehlmann, T Albanis, A Allera, J Bachmann, P Berntsson, ... Environmental health perspectives 114 (Suppl 1), 98-100, 2006 | 31 | 2006 |
Topoisomerase II is nonfunctional in polyamine‐depleted cells K Alm, P Berntsson, SM Oredsson Journal of cellular biochemistry 75 (1), 46-55, 1999 | 28 | 1999 |
Half-lives of ornithine decarboxylase and S-adenosylmethionine decarboxylase activities during the cell cycle of Chinese hamster ovary cells PSH Berntsson, K Alm, SM Oredsson Biochemical and biophysical research communications 263 (1), 13-16, 1999 | 15 | 1999 |
Effect of polyamine deficiency on proteins involved in Okazaki fragment maturation VM Johansson, MF Miniotis, C Hegardt, G Jönsson, J Staaf, ... Cell biology international 32 (12), 1467-1477, 2008 | 14 | 2008 |
Direct oral P2Y (12) receptor antagonist AZD6140 potently and reversibly binds to the Rh-P2Y (12) receptor expressed on CHO-K1 cells JJ van Giezen, PS Berntsson, BM Wissing ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 28 (6), E72-E72, 2008 | 12 | 2008 |
Comparing Flow Cytometry QBeads PlexScreen assays with other immunoassays for determining multiple analytes M Ding, A Cavallin, NO Hermansson, P Berntsson, L Jinton, ... SLAS DISCOVERY: Advancing Life Sciences R&D 23 (7), 676-686, 2018 | 10 | 2018 |
Optimization of ketone-based P2Y12 receptor antagonists as antithrombotic agents: Pharmacodynamics and receptor kinetics considerations F Giordanetto, P Bach, F Zetterberg, T Antonsson, R Bylund, J Johansson, ... Bioorganic & Medicinal Chemistry Letters 24 (13), 2963-2968, 2014 | 9 | 2014 |
AZD6140 displays over 100-fold higher affinity for the P2Y (12) receptor vs AZ11702105, a chemical compound indistinguishable from the active metabolite of prasugrel, and is a … JJ van Giezen, PS Berntsson ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 28 (6), E139-E140, 2008 | 8 | 2008 |
Melagatran-induced inhibition of thrombin generation is reversed by Feiba JC Ulvinge, P Berntsson, SL Bostrom Blood 96 (11), 2000 | 8 | 2000 |
HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD J Horndahl, R Svärd, P Berntsson, C Wingren, J Li, SM Abdillahi, B Ghosh, ... PloS one 17 (10), e0266310, 2022 | 7 | 2022 |
Induction of Diabetes Abolishes the Antithrombotic Effect of Clopidogrel in Apolipoprotein E–Deficient Mice A Sugidachi, K Ohno, JA Jakubowski, Y Ito, A Tomizawa, M Mizuno TH Open 1 (02), e92-e100, 2017 | 5 | 2017 |
An Angle on MK2 Inhibition—Optimization and Evaluation of Prevention of Activation Inhibitors U Hedström, M Norberg, E Evertsson, SR Lever, M Munck af Rosenschöld, ... ChemMedChem 14 (19), 1701-1709, 2019 | 4 | 2019 |
Comparative research on endocrine disrupters-Phylogenetic approach and common principles focussing on androgenic/antiandrogenic compounds-COMPRENDO: Final published report T Albanis, A Allera, J Bachmann, A Barbaglio, P Berntsson, N Beresford, ... EU-Energy, Environment and Sustainable Development, 2006 | 4 | 2006 |
AZD9567 versus prednisolone in patients with active rheumatoid arthritis: A phase IIa, randomized, double‐blind, efficacy, and safety study JM van Laar, A Lei, M Safy‐Khan, J Almquist, G Belfield, K Edman, ... Clinical and Translational Science 16 (12), 2494-2506, 2023 | 1 | 2023 |
Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism S Nylander, E Femia, M Scavone, P Berntsson, AK Asztély, L Löfgren, ... Arteriosclerosis, Thrombosis, and Vascular Biology 32 (suppl_1), A213-A213, 2012 | 1 | 2012 |