| Nrf2–ARE pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases I Buendia, P Michalska, E Navarro, I Gameiro, J Egea, R Leon Pharmacology & therapeutics 157, 84-104, 2016 | 525 | 2016 |
| European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ... Redox biology 13, 94-162, 2017 | 319 | 2017 |
| Redox control of microglial function: molecular mechanisms and functional significance AI Rojo, G McBean, M Cindric, J Egea, MG López, P Rada, N Zarkovic, ... Antioxidants & redox signaling 21 (12), 1766-1801, 2014 | 300 | 2014 |
| Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection J Egea, I Buendia, E Parada, E Navarro, R Leon, MG Lopez Biochemical pharmacology 97 (4), 463-472, 2015 | 290 | 2015 |
| The Microglial α7-Acetylcholine Nicotinic Receptor Is a Key Element in Promoting Neuroprotection by Inducing Heme Oxygenase-1 via Nuclear Factor Erythroid-2 … E Parada, J Egea, I Buendia, P Negredo, AC Cunha, S Cardoso, ... Antioxidants & redox signaling 19 (11), 1135-1148, 2013 | 199 | 2013 |
| A review of metal‐catalyzed molecular damage: protection by melatonin A Romero, E Ramos, C de Los Rios, J Egea, J Del Pino, RJ Reiter Journal of Pineal Research 56 (4), 343-370, 2014 | 179 | 2014 |
| Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis‐mediated cell death M Guerrero‐Hue, C García‐Caballero, A Palomino‐Antolín, ... The FASEB Journal 33 (8), 8961-8975, 2019 | 172 | 2019 |
| From single drug targets to synergistic network pharmacology in ischemic stroke AI Casas, AA Hassan, SJ Larsen, V Gomez-Rangel, M Elbatreek, ... Proceedings of the National Academy of Sciences 116 (14), 7129-7136, 2019 | 154 | 2019 |
| Na+ controls hypoxic signalling by the mitochondrial respiratory chain P Hernansanz-Agustín, C Choya-Foces, S Carregal-Romero, E Ramos, ... Nature 586 (7828), 287-291, 2020 | 149 | 2020 |
| Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal celldeath AI Rojo, P Rada, J Egea, AO Rosa, MG López, A Cuadrado Molecular and Cellular Neuroscience 39 (1), 125-132, 2008 | 133 | 2008 |
| Novel tacrine–benzofuran hybrids as potent multitarget-directed ligands for the treatment of Alzheimer’s disease: design, synthesis, biological evaluation, and X-ray … X Zha, D Lamba, L Zhang, Y Lou, C Xu, D Kang, L Chen, Y Xu, L Zhang, ... Journal of Medicinal Chemistry 59 (1), 114-131, 2016 | 131 | 2016 |
| Neuroprotectant minocycline depresses glutamatergic neurotransmission and Ca2+ signalling in hippocampal neurons JC González, J Egea, M Del Carmen Godino, FJ Fernandez‐Gomez, ... European Journal of Neuroscience 26 (9), 2481-2495, 2007 | 129 | 2007 |
| NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage AI Casas, E Geuss, PWM Kleikers, S Mencl, AM Herrmann, I Buendia, ... Proceedings of the National Academy of Sciences 114 (46), 12315-12320, 2017 | 127 | 2017 |
| Neuroprotective effect of melatonin against ischemia is partially mediated by alpha‐7 nicotinic receptor modulation and HO‐1 overexpression E Parada, I Buendia, R León, P Negredo, A Romero, A Cuadrado, ... Journal of pineal research 56 (2), 204-212, 2014 | 124 | 2014 |
| Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway T Dal-Cim, S Molz, J Egea, E Parada, A Romero, J Budni, ... Neurochemistry International 61 (3), 397-404, 2012 | 124 | 2012 |
| Antioxidant, antiinflammatory and neuroprotective actions of chondroitin sulfate and proteoglycans J Egea, AG García, J Verges, E Montell, MG López Osteoarthritis and Cartilage 18, S24-S27, 2010 | 119 | 2010 |
| Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia P Hernansanz-Agustín, E Ramos, E Navarro, E Parada, ... Redox Biology 12, 1040-1051, 2017 | 107 | 2017 |
| Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions T Dal‐Cim, FK Ludka, WC Martins, C Reginato, E Parada, J Egea, ... Journal of neurochemistry 126 (4), 437-450, 2013 | 106 | 2013 |
| Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in α7 nicotinic receptor knockout mice J Egea, AO Rosa, M Sobrado, L Gandia, MG Lopez, AG Garcia Neuroscience 145 (3), 866-872, 2007 | 106 | 2007 |
| The antioxidant additive approach for Alzheimer’s disease therapy: new ferulic (lipoic) acid plus melatonin modified tacrines as cholinesterases inhibitors, direct antioxidants … M Benchekroun, A Romero, J Egea, R Leon, P Michalska, I Buendia, ... Journal of medicinal chemistry 59 (21), 9967-9973, 2016 | 101 | 2016 |
