Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF‐C/D receptor VEGFR‐3 T Mäkinen, T Veikkola, S Mustjoki, T Karpanen, B Catimel, EC Nice, ... The EMBO journal, 2001 | 1145 | 2001 |
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ... New England journal of medicine 366 (20), 1905-1913, 2012 | 872 | 2012 |
Discontinuation of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia (EURO-SKI): a prespecified interim analysis of a prospective, multicentre, non-randomised, trial S Saussele, J Richter, J Guilhot, FX Gruber, H Hjorth-Hansen, A Almeida, ... The Lancet Oncology 19 (6), 747-757, 2018 | 566 | 2018 |
VEGFR-3 and CD133 identify a population of CD34+ lymphatic/vascular endothelial precursor cells P Salven, S Mustjoki, R Alitalo, K Alitalo, S Rafii Blood, The Journal of the American Society of Hematology 101 (1), 168-172, 2003 | 533 | 2003 |
Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia K Porkka, P Koskenvesa, T Lundán, J Rimpiläinen, S Mustjoki, R Smykla, ... Blood, The Journal of the American Society of Hematology 112 (4), 1005-1012, 2008 | 526 | 2008 |
Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease SE Flanagan, E Haapaniemi, MA Russell, R Caswell, HL Allen, ... Nature genetics 46 (8), 812-814, 2014 | 523 | 2014 |
STAT3 mutations unify the pathogenesis of chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte leukemia A Jerez, MJ Clemente, H Makishima, H Koskela, F LeBlanc, K Peng Ng, ... Blood, The Journal of the American Society of Hematology 120 (15), 3048-3057, 2012 | 452 | 2012 |
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ... Cancer discovery 3 (12), 1416-1429, 2013 | 451* | 2013 |
Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia A Giustacchini, S Thongjuea, N Barkas, PS Woll, BJ Povinelli, CAG Booth, ... Nature medicine 23 (6), 692-702, 2017 | 413 | 2017 |
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy S Mustjoki, M Ekblom, TP Arstila, I Dybedal, PK Epling-Burnette, F Guilhot, ... Leukemia 23 (8), 1398-1405, 2009 | 372 | 2009 |
Integrated drug profiling and CRISPR screening identify essential pathways for CAR T-cell cytotoxicity O Dufva, J Koski, P Maliniemi, A Ianevski, J Klievink, J Leitner, P Pölönen, ... Blood, The Journal of the American Society of Hematology 135 (9), 597-609, 2020 | 336* | 2020 |
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ... Blood, The Journal of the American Society of Hematology 121 (22), 4541-4550, 2013 | 334 | 2013 |
Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3 EM Haapaniemi, M Kaustio, HLM Rajala, AJ van Adrichem, L Kainulainen, ... Blood, The Journal of the American Society of Hematology 125 (4), 639-648, 2015 | 298 | 2015 |
Combination of pegylated IFN-α2b with imatinib increases molecular response rates in patients with low-or intermediate-risk chronic myeloid leukemia B Simonsson, T Gedde-Dahl, B Markevärn, K Remes, J Stentoft, ... Blood, The Journal of the American Society of Hematology 118 (12), 3228-3235, 2011 | 255 | 2011 |
Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia M Ilander, U Olsson-Strömberg, H Schlums, J Guilhot, O Brück, ... Leukemia 31 (5), 1108-1116, 2017 | 249 | 2017 |
Mono/oligoclonal T and NK cells are common in chronic myeloid leukemia patients at diagnosis and expand during dasatinib therapy A Kreutzman, V Juvonen, V Kairisto, M Ekblom, L Stenke, R Seggewiss, ... Blood, The Journal of the American Society of Hematology 116 (5), 772-782, 2010 | 207 | 2010 |
STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients A Jerez, MJ Clemente, H Makishima, H Rajala, I Gómez-Seguí, T Olson, ... Blood, The Journal of the American Society of Hematology 122 (14), 2453-2459, 2013 | 177 | 2013 |
Drug-perturbation-based stratification of blood cancer S Dietrich, M Oleś, J Lu, L Sellner, S Anders, B Velten, B Wu, J Huellein, ... The Journal of clinical investigation 128 (1), 427-445, 2018 | 156 | 2018 |
Increased level of myeloid-derived suppressor cells, programmed death receptor ligand 1/programmed death receptor 1, and soluble CD25 in Sokal high risk chronic myeloid leukemia L Christiansson, S Söderlund, E Svensson, S Mustjoki, M Bengtsson, ... PloS one 8 (1), e55818, 2013 | 151 | 2013 |
Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML R Warfvinge, L Geironson, MNE Sommarin, S Lang, C Karlsson, ... Blood, The Journal of the American Society of Hematology 129 (17), 2384-2394, 2017 | 144 | 2017 |