Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 11151 | 2021 |
Peroxiredoxin 1 functions as a signal peroxidase to receive, transduce, and transmit peroxide signals in mammalian cells RM Jarvis, SM Hughes, EC Ledgerwood Free Radical Biology and Medicine 53 (7), 1522-1530, 2012 | 326 | 2012 |
Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors AI Brooks, CS Stein, SM Hughes, J Heth, PM McCray Jr, SL Sauter, ... Proceedings of the National Academy of Sciences 99 (9), 6216-6221, 2002 | 187 | 2002 |
Diversity of layer 5 projection neurons in the mouse motor cortex MJ Oswald, MLS Tantirigama, I Sonntag, SM Hughes, RM Empson Frontiers in cellular neuroscience 7, 174, 2013 | 175 | 2013 |
Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors JM Alisky, SM Hughes, SL Sauter, D Jolly, TW Dubensky Jr, PD Staber, ... Neuroreport 11 (12), 2669-2673, 2000 | 172 | 2000 |
Transplanted adult neural progenitor cells survive, differentiate and reduce motor function impairment in a rodent model of Huntington's disease EM Vazey, K Chen, SM Hughes, B Connor Experimental neurology 199 (2), 384-396, 2006 | 151 | 2006 |
CNS transduction benefits of AAV-PHP. eB over AAV9 are dependent on administration route and mouse strain SN Mathiesen, JL Lock, L Schoderboeck, WC Abraham, SM Hughes Molecular Therapy-Methods & Clinical Development 19, 447-458, 2020 | 133 | 2020 |
Lentiviral vectors as tools to understand central nervous system biology in mammalian model organisms LC Parr-Brownlie, C Bosch-Bouju, L Schoderboeck, RJ Sizemore, ... Frontiers in molecular neuroscience 8, 14, 2015 | 133 | 2015 |
Viral-mediated gene transfer to mouse primary neural progenitor cells SM Hughes, F Moussavi-Harami, SL Sauter, BL Davidson Molecular Therapy 5 (1), 16-24, 2002 | 128 | 2002 |
AAV‐mediated delivery of BDNF augments neurogenesis in the normal and quinolinic acid‐lesioned adult rat brain RA Henry, SM Hughes, B Connor European Journal of Neuroscience 25 (12), 3513-3525, 2007 | 116 | 2007 |
Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system RE Haskell, SM Hughes, JA Chiorini, JM Alisky, BL Davidson Gene therapy 10 (1), 34-42, 2003 | 81 | 2003 |
Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer’s disease LCD Smyth, HC Murray, M Hill, E van Leeuwen, B Highet, NJ Magon, ... Acta neuropathologica communications 10 (1), 38, 2022 | 79 | 2022 |
Longitudinal in vivo monitoring of the CNS demonstrates the efficacy of gene therapy in a sheep model of CLN5 Batten disease NL Mitchell, KN Russell, MP Wellby, HE Wicky, L Schoderboeck, ... Molecular Therapy 26 (10), 2366-2378, 2018 | 77 | 2018 |
Cellular composition of human glial cultures from adult biopsy brain tissue HM Gibbons, SM Hughes, W Van Roon-Mom, JM Greenwood, ... Journal of neuroscience methods 166 (1), 89-98, 2007 | 64 | 2007 |
Lentivirus-mediated expression of human secreted amyloid precursor protein-alpha prevents development of memory and plasticity deficits in a mouse model of Alzheimer's disease VTY Tan, BG Mockett, SM Ohline, KD Parfitt, HE Wicky, K Peppercorn, ... Molecular brain 11, 1-16, 2018 | 61 | 2018 |
Creating a neurogenic environment: the role of BDNF and FGF2 K Chen, RA Henry, SM Hughes, B Connor Molecular and Cellular Neuroscience 36 (1), 108-120, 2007 | 61 | 2007 |
Lentiviral-mediated gene transfer to the sheep brain: implications for gene therapy in Batten disease KS Linterman, DN Palmer, GW Kay, LA Barry, NL Mitchell, RG McFarlane, ... Human gene therapy 22 (8), 1011-1020, 2011 | 55 | 2011 |
Temporal profile of subventricular zone progenitor cell migration following quinolinic acid–induced striatal cell loss RJ Gordon, AS Tattersfield, EM Vazey, AP Kells, AL McGregor, ... Neuroscience 146 (4), 1704-1718, 2007 | 55 | 2007 |
Gene therapy corrects brain and behavioral pathologies in CLN6-Batten disease JT Cain, S Likhite, KA White, DJ Timm, SS Davis, TB Johnson, ... Molecular Therapy 27 (10), 1836-1847, 2019 | 50 | 2019 |
Patterned, but not tonic, optogenetic stimulation in motor thalamus improves reaching in acute drug-induced Parkinsonian rats S Seeger-Armbruster, C Bosch-Bouju, STC Little, RA Smither, SM Hughes, ... Journal of Neuroscience 35 (3), 1211-1216, 2015 | 49 | 2015 |