Hyperbranched polyglycerols: recent advances in synthesis, biocompatibility and biomedical applications S Abbina, S Vappala, P Kumar, EMJ Siren, CC La, U Abbasi, DE Brooks, ... Journal of Materials Chemistry B 5 (47), 9249-9277, 2017 | 159 | 2017 |
Smart thrombosis inhibitors without bleeding side effects via charge tunable ligand design CC La, SA Smith, S Vappala, R Adili, CE Luke, S Abbina, HD Luo, ... Nature Communications 14 (1), 2177, 2023 | 15 | 2023 |
Targeting biological polyanions in blood: strategies toward the design of therapeutics CC La, LE Takeuchi, S Abbina, S Vappala, U Abbasi, JN Kizhakkedathu Biomacromolecules 21 (7), 2595-2621, 2020 | 10 | 2020 |
DNAse-mediated dissolution of neutrophil extracellular traps accelerates in vitro thrombin generation kinetics in trauma patients J Goswami, TA MacArthur, C Mahony, JN Kizhakkedathu, S Vappala, ... Shock 58 (3), 217-223, 2022 | 6 | 2022 |
Development of a high-throughput urosepsis mouse model R Herout, S Vappala, S Hanstock, I Moskalev, BH Chew, ... Pathogens 12 (4), 604, 2023 | 3 | 2023 |
Influence of steric shield on biocompatibility and antithrombotic activity of dendritic polyphosphate inhibitor S Abbina, CC La, S Vappala, MT Kalathottukaren, U Abbasi, A Gill, ... Molecular pharmaceutics 19 (6), 1853-1865, 2022 | 3 | 2022 |
Rheological and clot microstructure evaluation of heparin neutralization by UHRA and protamine HH Yeh, K Yu, S Vappala, MT Kalathottukaren, S Abbina, HD Luo, ... Journal of the Mechanical Behavior of Biomedical Materials 124, 104851, 2021 | 3 | 2021 |
A nanoparticle-preparation kit using ethylene glycol-based block copolymers with a common temperature-responsive block Y Kotsuchibashi, CM Lee, I Constantinescu, LE Takeuchi, S Vappala, ... Polymer Chemistry 8 (47), 7311-7315, 2017 | 2 | 2017 |
Inhibitors of polyphosphate and neutrophil extracellular traps S Vappala, SA Smith, JN Kizhakkedathu, JH Morrissey Seminars in Thrombosis and Hemostasis, 2023 | 1 | 2023 |
PB0416 Platelet Polyphosphate Activates NFκB Signaling to Induce Myofibroblast Differentiation P Suess, C La, S Vappala, J Kizhakkedathu, J Morrissey Research and Practice in Thrombosis and Haemostasis 7, 2023 | | 2023 |
PB0590 The Control of Protein Binding on Bio-Interface by a Novel Coating to Prevent Contact Activation on Biomaterials H Ji, T Xu, K Yu, S Vappala, J Kizhakkedathu Research and Practice in Thrombosis and Haemostasis 7, 2023 | | 2023 |
OC 55.5 Safe Nucleic Acid Inhibitors that Show Protection Against Immunothrombosis in Sepsis S Vappala, A Reicherz, C La, H Ji, S Abbina, M Kalathottukaren, ... Research and Practice in Thrombosis and Haemostasis 7, 2023 | | 2023 |
OC 62.5 Next-Generation, Dendrimer-Like Polyphosphate Inhibitor is a Safe and Effective Antithrombotic Agent S Smith, C La, S Vappala, R Adili, C Luke, S Abbina, H Luo, I Chafeeva, ... Research and Practice in Thrombosis and Haemostasis 7, 2023 | | 2023 |
PD19-04 A NOVEL, HIGH-THROUGHPUT UROSEPSIS MOUSE MODEL R Herout, S Vappala, S Hanstock, I Moskalev, BH Chew, ... Journal of Urology 209 (Supplement 4), e578, 2023 | | 2023 |
INHIBITORS OF INORGANIC POLYPHOSPHATE AND NUCLEIC ACIDS LEAD TO DECREASED THROMBIN GENERATION IN TRAUMA PATIENTS TA MacArthur, J Goswami, S Vappala, J Zietlow, SA Smith, JH Morrissey, ... AMERICAN JOURNAL OF HEMATOLOGY 98, E67-E68, 2023 | | 2023 |
Inhibitors of Inorganic Polyphosphate and Nucleic Acids Attenuate in vitro Thrombin Generation in Plasma from Trauma Patients TA MacArthur, J Goswami, SM Navarro, S Vappala, CC La, N Yudin, ... Shock, 10.1097, 2023 | | 2023 |
Polycationic inhibitors to target prothrombotic nucleic acids in vitro and in mouse models S Vappala University of British Columbia, 2023 | | 2023 |
DNA Mediated Blood Coagulation: Extracellular DNA Accelerates Fibrinogen Polymerization By Thrombin Independent of Contact Pathway S Vappala, S Straus, EL Pryzdial, E Conway, J Kizhakkedathu Blood 138, 2101, 2021 | | 2021 |
A UNIVERSAL HEPARIN REVERSAL AGENT DEMONSTRATES NEGLIGIBLE EFFECT ON PLATELETS, ENDOTHELIAL CELLS AND REVERSES PROFIBRINOLYTIC ACTIVITY OF HEPARIN S Vappala, MT Kalathottukaren, U Abbasi, S Abbina, I Constantinescu, ... AMERICAN JOURNAL OF HEMATOLOGY 93 (9), E68-E69, 2018 | | 2018 |
The control of protein binding on bio-interface by a novel coating to prevent contact activation on biomaterials HF Ji, K Yu, S Abbina, L Xu, T Xu, SJ Cheng, S Vappala, A Arefi, ... | | |