Enantioselective, intermolecular benzylic C–H amination catalysed by an engineered iron-haem enzyme CK Prier, RK Zhang, AR Buller, S Brinkmann-Chen, FH Arnold Nature chemistry 9 (7), 629-634, 2017 | 376 | 2017 |
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp 3 C–H functionalization - Nature cover RK Zhang, K Chen, X Huang, L Wohlschlager, H Renata, FH Arnold Nature 565 (7737), 67-72, 2019 | 291 | 2019 |
Enzymatic construction of highly strained carbocycles K Chen, X Huang, SBJ Kan, RK Zhang, FH Arnold Science 360 (6384), 71-75, 2018 | 228 | 2018 |
Enantioselective enzyme-catalyzed aziridination enabled by active-site evolution of a cytochrome P450 CC Farwell, RK Zhang, JA McIntosh, TK Hyster, FH Arnold ACS central science 1 (2), 89-93, 2015 | 185 | 2015 |
Selective CH bond functionalization with engineered heme proteins: new tools to generate complexity RK Zhang, X Huang, FH Arnold Current opinion in chemical biology 49, 67-75, 2019 | 126 | 2019 |
Enantiodivergent α-amino C–H fluoroalkylation catalyzed by engineered cytochrome P450s J Zhang, X Huang, RK Zhang, FH Arnold Journal of the American Chemical Society 141 (25), 9798-9802, 2019 | 115 | 2019 |
Enantioselective aminohydroxylation of styrenyl olefins catalyzed by an engineered hemoprotein I Cho, CK Prier, ZJ Jia, RK Zhang, T Görbe, FH Arnold Angewandte Chemie International Edition 58 (10), 3138-3142, 2019 | 102 | 2019 |
Directed evolution of a bright near-infrared fluorescent rhodopsin using a synthetic chromophore L Herwig, AJ Rice, CN Bedbrook, RK Zhang, A Lignell, JKB Cahn, ... Cell chemical biology 24 (3), 415-425, 2017 | 69 | 2017 |
Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Ligands NW Goldberg, AM Knight, RK Zhang, FH Arnold Journal of the American Chemical Society 141 (50), 19585-19588, 2019 | 62 | 2019 |
Development of Scalable Processes with Underutilized Biocatalyst Classes RM Phelan, MJ Abrahamson, JTC Brown, RK Zhang, CR Zwick III Organic Process Research & Development 26 (7), 1944-1959, 2022 | 5 | 2022 |
Method for enantioselective carbene C–H insertion using an iron-containing protein catalyst. RK Zhang, L Wohlschlager, H Renata, FH Arnold, K Chen US10934531B2, 2021 | 1 | 2021 |
Directed Evolution of Artificial Metalloenzymes: Bridging Synthetic Chemistry and Biology RK Zhang, DK Romney, SBJ Kan, FH Arnold Artificial Metalloenzymes and MetalloDNAzymes in Catalysis: From Design to …, 2018 | 1 | 2018 |