Cancer-associated SF3B1 mutants recognize otherwise inaccessible cryptic 3′ splice sites within RNA secondary structures AK Kesarwani, O Ramirez, AK Gupta, X Yang, T Murthy, AC Minella, ... Oncogene 36 (8), 1123-1133, 2017 | 84 | 2017 |
Self-circularizing 5′-ETS RNAs accumulate along with unprocessed pre ribosomal RNAs in growth-stressed Entamoeba histolytica AK Gupta, SK Panigrahi, A Bhattacharya, S Bhattacharya Scientific reports 2 (1), 303, 2012 | 30 | 2012 |
Cyclin-dependent kinase 1 (CDK1) and CDK2 have opposing roles in regulating interactions of splicing factor 3B1 with chromatin T Murthy, T Bluemn, AK Gupta, M Reimer, S Rao, MM Pillai, AC Minella Journal of Biological Chemistry 293 (26), 10220-10234, 2018 | 17 | 2018 |
Differential distribution of a SINE element in the Entamoeba histolytica and Entamoeba dispar genomes: Role of the LINE-encoded endonuclease V Kumari, R Sharma, VP Yadav, AK Gupta, A Bhattacharya, ... BMC genomics 12, 1-12, 2011 | 15 | 2011 |
Multi-omics investigation of innate navitoclax resistance in triple-negative breast cancer cells M Marczyk, GA Patwardhan, J Zhao, R Qu, X Li, VB Wali, AK Gupta, ... Cancers 12 (9), 2551, 2020 | 14 | 2020 |
Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2) S Karmakar, O Ramirez, KV Paul, AK Gupta, V Kumari, V Botti, ... NAR cancer 4 (2), zcac015, 2022 | 11 | 2022 |
Degenerate minigene library analysis enables identification of altered branch point utilization by mutant splicing factor 3B1 (SF3B1) AK Gupta, T Murthy, KV Paul, O Ramirez, JB Fisher, S Rao, ... Nucleic acids research 47 (2), 970-980, 2019 | 11 | 2019 |
Computational prediction and validation of C/D, H/ACA and Eh_U3 snoRNAs of Entamoeba histolytica D Kaur, AK Gupta, V Kumari, R Sharma, A Bhattacharya, S Bhattacharya BMC genomics 13, 1-20, 2012 | 10 | 2012 |
Generation of scalable cancer models by combining AAV-intron-trap, CRISPR/Cas9, and inducible Cre-recombinase PC Boddu, AK Gupta, JS Kim, KM Neugebauer, T Waldman, MM Pillai Communications Biology 4 (1), 1184, 2021 | 8 | 2021 |
Rationally designed inhibitors of the Musashi protein-RNA interaction by hotspot mimicry N Bai, Y Adeshina, I Bychkov, Y Xia, R Gowthaman, SA Miller, AK Gupta, ... bioRxiv, 2023 | 4 | 2023 |
Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape PC Boddu, AK Gupta, R Roy, BDLP Avalos, A Olazabal-Herrero, ... Molecular Cell 84 (8), 1475-1495. e18, 2024 | 3 | 2024 |
The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export A Olazabal-Herrero, B He, Y Kwon, AK Gupta, A Dutta, Y Huang, P Boddu, ... Cell reports 43 (1), 2024 | 3 | 2024 |
Transcription elongation defects link oncogenic splicing factor mutations to targetable alterations in chromatin landscape PC Boddu, AK Gupta, R Roy, BDL Pena Avalos, AO Herrero, ... bioRxiv, 2023.02. 25.530019, 2023 | 2 | 2023 |
Integrative analysis of RNA-Interactome and translatome reveal functional targets of MSI2 in myeloid leukemia O Ramirez, A Kesarwani, G Abhishek, AC Minella, MM Pillai Blood 128 (22), 1881, 2016 | 2 | 2016 |
Ribosomal RNA Genes and Their Regulation in Entamoeba histolytica AK Gupta, S Bhattacharya Amebiasis: Biology and Pathogenesis of Entamoeba, 119-135, 2015 | 1 | 2015 |
Transcription Defects in SF3B1K700E Induce Targetable Alterations in the Chromatin Landscape P Boddu, A Gupta, R Roy, AO Herrero, A Verma, K Neugebauer, M Pillai Blood 142, 709, 2023 | | 2023 |
Impaired Early Spliceosome Complex Assembly Underlies Gene Body Elongation Transcription Defect in SF3B1K700E P Boddu, A Gupta, R Roy, AO Herrero, J Zimmer, M Simon, NS Chandhok, ... Blood 142, 714, 2023 | | 2023 |
The Fanconi Anemia pathway protein complex FANCI/FANCD2 couples the DNA damage response to R-loop regulation through SRSF1-mediated mRNA export A Olazabal-Herrero, F Liang, A Dutta, Y Huang, Z Liang, A Gupta, Y Teng, ... Cancer Research 83 (7_Supplement), 6100-6100, 2023 | | 2023 |
Complex Formation between FANCD2 and the Splicing Factor SRSF1 Helps Prevent R-Loop Accumulation through mRNA Export Regulation A Olazabal Herrero, F Liang, A Dutta, Y Huang, Z Liang, AK Gupta, L Lan, ... Blood 140 (Supplement 1), 5828-5829, 2022 | | 2022 |
Binding of FANCD2 to SRSF1 splicing factor prevents R-loop accumulation through mRNA export regulation GMK Anne Olazabal-Herrero, Fengshan Liang,Arijit Dutta,Yuxin Huang,Zhuobin ... Fanconi Anemia Symposium, 44-45, 2022 | | 2022 |