Pazopanib for treatment of advanced malignant and dedifferentiated solitary fibrous tumour: a multicentre, single-arm, phase 2 trial J Martin-Broto, S Stacchiotti, A Lopez-Pousa, A Redondo, D Bernabeu, ... The Lancet Oncology 20 (1), 134-144, 2019 | 109 | 2019 |
Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial J Martin-Broto, N Hindi, G Grignani, J Martinez-Trufero, A Redondo, ... Journal for ImmunoTherapy of Cancer 8 (2), e001561, 2020 | 107 | 2020 |
High stability of microRNAs in tissue samples of compromised quality L Peiró-Chova, M Peña-Chilet, JA López-Guerrero, JL García-Giménez, ... Virchows Archiv 463 (6), 765-774, 2013 | 98 | 2013 |
COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms M Ostaszewski, A Niarakis, A Mazein, I Kuperstein, R Phair, ... bioRxiv, 2020 | 85* | 2020 |
MicroRNA profile in very young women with breast cancer M Peña-Chilet, MT Martínez, JA Pérez-Fidalgo, L Peiró-Chova, SS Oltra, ... Bmc Cancer 14 (1), 529, 2014 | 73 | 2014 |
Pazopanib for treatment of typical solitary fibrous tumours: a multicentre, single-arm, phase 2 trial J Martin-Broto, J Cruz, N Penel, A Le Cesne, N Hindi, P Luna, DS Moura, ... The Lancet Oncology 21 (3), 456-466, 2020 | 66 | 2020 |
Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection C Loucera, M Esteban-Medina, K Rian, MM Falco, J Dopazo, ... Signal transduction and targeted therapy 5 (1), 1-3, 2020 | 61 | 2020 |
Gender is a major factor explaining discrepancies in eye colour prediction based on HERC2/OCA2 genotype and the IrisPlex model C Martinez-Cadenas, M Peña-Chilet, M Ibarrola-Villava, G Ribas Forensic Science International: Genetics 7 (4), 453-460, 2013 | 55 | 2013 |
Genetic polymorphisms in DNA repair and oxidative stress pathways associated with malignant melanoma susceptibility M Ibarrola-Villava, M Peña-Chilet, LP Fernandez, JA Aviles, M Mayor, ... European Journal of Cancer 47 (17), 2618-2625, 2011 | 53 | 2011 |
Methylation deregulation of miRNA promoters identifies miR124-2 as a survival biomarker in Breast Cancer in very young women SS Oltra, M Peña-Chilet, V Vidal-Tomas, K Flower, MT Martinez, E Alonso, ... Scientific reports 8 (1), 1-12, 2018 | 52 | 2018 |
Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population M Peña-Chilet, M Blanquer-Maceiras, M Ibarrola-Villava, ... BMC cancer 13 (1), 160, 2013 | 52 | 2013 |
CSVS, a crowdsourcing database of the Spanish population genetic variability M Peña-Chilet, G Roldán, J Perez-Florido, FM Ortuño, R Carmona, ... Nucleic Acids Research 49 (D1), D1130-D1137, 2021 | 47 | 2021 |
Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin B Hernando, M Ibarrola-Villava, LP Fernandez, M Peña-Chilet, ... Biology of sex differences 7 (1), 17, 2016 | 43 | 2016 |
Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk MJ Llorca-Cardeñosa, M Peña-Chilet, M Mayor, C Gomez-Fernandez, ... European Journal of Cancer 50 (18), 3168-3177, 2014 | 42 | 2014 |
Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models M Esteban-Medina, M Peña-Chilet, C Loucera, J Dopazo BMC bioinformatics 20 (1), 370, 2019 | 30 | 2019 |
A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene M Ibarrola-Villava, LP Fernandez, S Alonso, MD Boyano, M Peña-Chilet, ... PloS one 6 (4), e19271, 2011 | 30 | 2011 |
rs12512631 on the group specific complement (vitamin D-binding protein GC) implicated in melanoma susceptibility M Peña-Chilet, M Ibarrola-Villava, M Martin-González, M Feito, ... PloS one 8 (3), e59607, 2013 | 28 | 2013 |
Breast Cancer in Very Young Patients in a Spanish Cohort: Age as an Independent Bad Prognostic Indicator MT Martínez, SS Oltra, M Peña-Chilet, E Alonso, C Hernando, O Burgues, ... Breast cancer: basic and clinical research 13, 1178223419828766, 2019 | 27 | 2019 |
Using mechanistic models for the clinical interpretation of complex genomic variation M Peña-Chilet, M Esteban-Medina, MM Falco, K Rian, MR Hidalgo, ... Scientific Reports 9 (1), 1-12, 2019 | 23 | 2019 |
Mechanistic modeling of the SARS-CoV-2 disease map K Rian, M Esteban-Medina, MR Hidalgo, C Cubuk, MM Falco, C Loucera, ... BioRxiv, 2020 | 22 | 2020 |