Specific substitutions in the echinocandin target Fks1p account for reduced susceptibility of rare laboratory and clinical Candida sp. isolates. PDS Park S, Kelly R, Kahn JN, Robles J, Hsu MJ, Register E, Li W, Vyas V ... Antimicrob Agents Chemother 49 (8), 3264-73, 2005 | 520 | 2005 |
A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families VK Vyas, MI Barrasa, GR Fink Science advances 1 (3), e1500248, 2015 | 386 | 2015 |
Snf1 protein kinase and the repressors Nrg1 and Nrg2 regulate FLO11, haploid invasive growth, and diploid pseudohyphal differentiation S Kuchin, VK Vyas, M Carlson Molecular and cellular biology, 2002 | 271 | 2002 |
Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages A Esteban, MW Popp, VK Vyas, K Strijbis, HL Ploegh, GR Fink Proceedings of the National Academy of Sciences 108 (34), 14270-14275, 2011 | 168 | 2011 |
Bruton's Tyrosine Kinase (BTK) and Vav1 Contribute to Dectin1-Dependent Phagocytosis of Candida albicans in Macrophages K Strijbis, FG Tafesse, GD Fairn, MD Witte, SK Dougan, N Watson, ... PLoS pathogens 9 (6), e1003446, 2013 | 99 | 2013 |
Interaction of the Srb10 kinase with Sip4, a transcriptional activator of gluconeogenic genes in Saccharomyces cerevisiae O Vincent, S Kuchin, SP Hong, R Townley, VK Vyas, M Carlson Molecular and cellular biology, 2001 | 95 | 2001 |
Snf1 kinases with different β-subunit isoforms play distinct roles in regulating haploid invasive growth VK Vyas, S Kuchin, CD Berkey, M Carlson Molecular and cellular biology 23 (4), 1341-1348, 2003 | 94 | 2003 |
Interaction of the Repressors Nrg1 and Nrg2 With the Snf1 Protein Kinase in Saccharomyces cerevisiae VK Vyas, S Kuchin, M Carlson Genetics 158 (2), 563-572, 2001 | 90 | 2001 |
Repressors Nrg1 and Nrg2 Regulate a Set of Stress-Responsive Genes in Saccharomyces cerevisiae VK Vyas, CD Berkey, T Miyao, M Carlson Eukaryotic Cell 4 (11), 1882-1891, 2005 | 87 | 2005 |
New CRISPR mutagenesis strategies reveal variation in repair mechanisms among fungi VK Vyas, GG Bushkin, DA Bernstein, MA Getz, M Sewastianik, MI Barrasa, ... MSphere 3 (2), 10.1128/msphere. 00154-18, 2018 | 85 | 2018 |
A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families. Sci Adv 1: e1500248 VK Vyas, MI Barrasa, GR Fink | 73 | 2015 |
Nrg1 and Nrg2 transcriptional repressors are differently regulated in response to carbon source CD Berkey, VK Vyas, M Carlson Eukaryotic Cell 3 (2), 311-317, 2004 | 69 | 2004 |
Candida albicans Dicer (CaDcr1) is required for efficient ribosomal and spliceosomal RNA maturation DA Bernstein, VK Vyas, DE Weinberg, IA Drinnenberg, DP Bartel, GR Fink Proceedings of the National Academy of Sciences 109 (2), 523-528, 2012 | 65 | 2012 |
The Candida glabrata adhesin Epa1p causes adhesion, phagocytosis, and cytokine secretion by innate immune cells DM Kuhn, VK Vyas FEMS yeast research 12 (4), 398-414, 2012 | 48 | 2012 |
Role of the yeast Snf1 protein kinase in invasive growth S Kuchin, VK Vyas, M Carlson Biochemical Society transactions 31 (1), 175-177, 2003 | 47 | 2003 |
Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space AO Veri, Z Miao, RS Shapiro, F Tebbji, TR O’Meara, SH Kim, J Colazo, ... PLoS genetics 14 (3), e1007270, 2018 | 46 | 2018 |
Compositions And Methods For Genetically Modifying Yeast VK Vyas, GR Fink US Patent App. 15/089,472, 2017 | 40 | 2017 |
Std1p (Msn3p) Positively Regulates the Snf1 Kinase in Saccharomyces cerevisiae S Kuchin, VK Vyas, E Kanter, SP Hong, M Carlson Genetics 163 (2), 507-514, 2003 | 39 | 2003 |
Reducing phenolic off-flavors through CRISPR-based gene editing of the FDC1 gene in Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid lager … S Mertens, B Gallone, J Steensels, B Herrera-Malaver, J Cortebeek, ... PLoS One 14 (1), e0209124, 2019 | 34 | 2019 |
CpALS4770 and CpALS4780 contribution to the virulence of Candida parapsilosis M Zoppo, M Di Luca, M Franco, C Rizzato, A Lupetti, A Stringaro, ... Microbiological research 231, 126351, 2020 | 16 | 2020 |