Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases J Zheng, V Haberland, D Baird, V Walker, PC Haycock, MR Hurle, ... Nature Genetics 52 (10), 1122-1131, 2020 | 433 | 2020 |
Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales R Knight, V Walker, S Ip, JA Cooper, T Bolton, S Keene, R Denholm, ... Circulation 146 (12), 892-906, 2022 | 187 | 2022 |
Mendelian randomization: a novel approach for the prediction of adverse drug events and drug repurposing opportunities VM Walker, G Davey Smith, NM Davies, RM Martin International journal of epidemiology 46 (6), 2078-2089, 2017 | 162 | 2017 |
Mendelian randomization for studying the effects of perturbing drug targets D Gill, MK Georgakis, VM Walker, AF Schmidt, A Gkatzionis, DF Freitag, ... Wellcome Open Research 6, 2021 | 157 | 2021 |
Linked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource A Wood, R Denholm, S Hollings, J Cooper, S Ip, V Walker, S Denaxas, ... bmj 373, 2021 | 144 | 2021 |
Cardiometabolic Traits, Sepsis, and Severe COVID-19: A Mendelian Randomization Investigation MJ Ponsford, A Gkatzionis, VM Walker, AJ Grant, RE Wootton, LSP Moore, ... Circulation 142 (18), 1791-1793, 2020 | 124 | 2020 |
Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes VM Walker, NM Davies, G Hemani, J Zheng, PC Haycock, TR Gaunt, ... Wellcome Open Research 4, 2019 | 98 | 2019 |
Repurposing antihypertensive drugs for the prevention of Alzheimer’s disease: a Mendelian randomization study VM Walker, PG Kehoe, RM Martin, NM Davies International journal of epidemiology 49 (4), 1132-1140, 2020 | 75 | 2020 |
Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England WN Whiteley, S Ip, JA Cooper, T Bolton, S Keene, V Walker, R Denholm, ... PLoS medicine 19 (2), e1003926, 2022 | 70 | 2022 |
Prioritizing the role of major lipoproteins and subfractions as risk factors for peripheral artery disease MG Levin, V Zuber, VM Walker, D Klarin, J Lynch, R Malik, AW Aday, ... Circulation 144 (5), 353-364, 2021 | 55 | 2021 |
Evaluating the efficacy and mechanism of metformin targets on reducing Alzheimer’s disease risk in the general population: a Mendelian randomisation study J Zheng, M Xu, V Walker, J Yuan, R Korologou-Linden, J Robinson, ... Diabetologia 65 (10), 1664-1675, 2022 | 52 | 2022 |
Waning effectiveness of BNT162b2 and ChAdOx1 covid-19 vaccines over six months since second dose: OpenSAFELY cohort study using linked electronic health records EMF Horne, WJ Hulme, RH Keogh, TM Palmer, EJ Williamson, ... bmj 378, 2022 | 49 | 2022 |
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease J Zheng, Y Zhang, H Rasheed, V Walker, Y Sugawara, J Li, Y Leng, ... International journal of epidemiology 50 (6), 1995-2010, 2021 | 46 | 2021 |
Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers: A mendelian randomization analysis J Yarmolinsky, V Díez-Obrero, TG Richardson, M Pigeyre, J Sjaarda, ... PLoS medicine 19 (2), e1003897, 2022 | 41 | 2022 |
Strategies to investigate and mitigate collider bias in genetic and Mendelian randomisation studies of disease progression RE Mitchell, AE Hartley, VM Walker, A Gkatzionis, J Yarmolinsky, JA Bell, ... PLoS genetics 19 (2), e1010596, 2023 | 30 | 2023 |
Association Between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease MG Levin, D Klarin, VM Walker, D Gill, J Lynch, JN Hellwege, JM Keaton, ... Arteriosclerosis, Thrombosis, and Vascular Biology 41 (6), 2027-2034, 2021 | 29 | 2021 |
Comparative effectiveness of BNT162b2 versus mRNA-1273 covid-19 vaccine boosting in England: matched cohort study in OpenSAFELY-TPP WJ Hulme, EMF Horne, EPK Parker, RH Keogh, EJ Williamson, V Walker, ... bmj 380, 2023 | 27* | 2023 |
Effects of general and central adiposity on circulating lipoprotein, lipid, and metabolite levels in UK Biobank: a multivariable Mendelian randomization study JA Bell, TG Richardson, Q Wang, E Sanderson, T Palmer, V Walker, ... The Lancet Regional Health–Europe 21, 2022 | 25* | 2022 |
Comparison of antihypertensive drug classes for dementia prevention VM Walker, NM Davies, RM Martin, PG Kehoe Epidemiology 31 (6), 852-859, 2020 | 24 | 2020 |
Genetically predicted blood pressure and risk of atrial fibrillation MC Hyman, MG Levin, D Gill, VM Walker, MK Georgakis, NM Davies, ... Hypertension 77 (2), 376-382, 2021 | 21 | 2021 |