Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. M Harel, I Schalk, L Ehret-Sabatier, F Bouet, M Goeldner, C Hirth, ... Proceedings of the National Academy of Sciences 90 (19), 9031-9035, 1993 | 1168 | 1993 |
The E46K mutation in α-synuclein increases amyloid fibril formation EA Greenbaum, CL Graves, AJ Mishizen-Eberz, MA Lupoli, DR Lynch, ... Journal of Biological Chemistry 280 (9), 7800-7807, 2005 | 502 | 2005 |
Role of α-synuclein carboxy-terminus on fibril formation in vitro IVJ Murray, BI Giasson, SM Quinn, V Koppaka, PH Axelsen, ... Biochemistry 42 (28), 8530-8540, 2003 | 469 | 2003 |
An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase. DR Ripoll, CH Faerman, PH Axelsen, I Silman, JL Sussman Proceedings of the National Academy of Sciences 90 (11), 5128-5132, 1993 | 372 | 1993 |
Open" back door" in a molecular dynamics simulation of acetylcholinesterase MK Gilson, TP Straatsma, JA McCammon, DR Ripoll, CH Faerman, ... Science 263 (5151), 1276-1278, 1994 | 364 | 1994 |
Copper and oxidative stress in the pathogenesis of Alzheimer’s disease G Eskici, PH Axelsen Biochemistry 51 (32), 6289-6311, 2012 | 301 | 2012 |
Mass spectrometric analysis of long‐chain lipids RC Murphy, PH Axelsen Mass spectrometry reviews 30 (4), 579-599, 2011 | 264 | 2011 |
Folding of β-sheet membrane proteins: a hydrophobic hexapeptide model WC Wimley, K Hristova, AS Ladokhin, L Silvestro, PH Axelsen, SH White Journal of molecular biology 277 (5), 1091-1110, 1998 | 236 | 1998 |
Structure and dynamics of the active site gorge of acetylcholinesterase: synergistic use of molecular dynamics simulation and X‐ray crystallography PH Axelsen, M Harel, I Silman, JL Sussman Protein Science 3 (2), 188-197, 1994 | 235 | 1994 |
Oxidative stress and cell membranes in the pathogenesis of Alzheimer's disease PH Axelsen, H Komatsu, IVJ Murray Physiology 26 (1), 54-69, 2011 | 215 | 2011 |
Simultaneous recognition of a carboxylate-containing ligand and an intramolecular surrogate ligand in the crystal structure of an asymmetric vancomycin dimer PJ Loll, AE Bevivino, BD Korty, PH Axelsen Journal of the American Chemical Society 119 (7), 1516-1522, 1997 | 192 | 1997 |
2D IR provides evidence for mobile water molecules in β-amyloid fibrils YS Kim, L Liu, PH Axelsen, RM Hochstrasser Proceedings of the National Academy of Sciences 106 (42), 17751-17756, 2009 | 190 | 2009 |
The structure of human lipoprotein AI: evidence for the “belt” model V Koppaka, L Silvestro, JA Engler, CG Brouillette, PH Axelsen Journal of Biological Chemistry 274 (21), 14541-14544, 1999 | 181 | 1999 |
Accelerated accumulation of amyloid β proteins on oxidatively damaged lipid membranes V Koppaka, PH Axelsen Biochemistry 39 (32), 10011-10016, 2000 | 168 | 2000 |
Antibacterial and Antimembrane Activities of Cecropin A in Escherichia coli L Silvestro, JN Weiser, PH Axelsen Antimicrobial agents and chemotherapy 44 (3), 602-607, 2000 | 165 | 2000 |
The concentration-dependent membrane activity of cecropin A L Silvestro, K Gupta, JN Weiser, PH Axelsen Biochemistry 36 (38), 11452-11460, 1997 | 165 | 1997 |
Two-dimensional infrared spectra of isotopically diluted amyloid fibrils from Aβ40 YS Kim, L Liu, PH Axelsen, RM Hochstrasser Proceedings of the National Academy of Sciences 105 (22), 7720-7725, 2008 | 156 | 2008 |
Buried water in homologous serine proteases U Sreenivasan, PH Axelsen Biochemistry 31 (51), 12785-12791, 1992 | 144 | 1992 |
The structural biology of molecular recognition by vancomycin PJ Loll, PH Axelsen Annual review of biophysics and biomolecular structure 29 (1), 265-289, 2000 | 140 | 2000 |
Promotion of oxidative lipid membrane damage by amyloid β proteins IVJ Murray, ME Sindoni, PH Axelsen Biochemistry 44 (37), 12606-12613, 2005 | 139 | 2005 |