Small-cell carcinoma of the ovary, hypercalcemic type–genetics, new treatment targets, and current management guidelines M Tischkowitz, S Huang, S Banerjee, J Hague, WPD Hendricks, ... Clinical Cancer Research 26 (15), 3908-3917, 2020 | 128 | 2020 |
The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type Y Wang, SY Chen, AN Karnezis, S Colborne, ND Santos, JD Lang, ... The Journal of pathology 242 (3), 371-383, 2017 | 107 | 2017 |
Insulin‐like growth factor‐2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer S Bhusari, B Yang, J Kueck, W Huang, DF Jarrard The Prostate 71 (15), 1621-1630, 2011 | 86 | 2011 |
Histone deacetylase inhibitors synergize with catalytic inhibitors of EZH2 to exhibit antitumor activity in small cell carcinoma of the ovary, hypercalcemic type Y Wang, SY Chen, S Colborne, G Lambert, CY Shin, ND Santos, ... Molecular cancer therapeutics 17 (12), 2767-2779, 2018 | 78 | 2018 |
Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multikinase inhibition JD Lang, WPD Hendricks, KA Orlando, H Yin, J Kiefer, P Ramos, ... Clinical Cancer Research 24 (8), 1932-1943, 2018 | 71 | 2018 |
The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer R Soldi, T Ghosh Halder, A Weston, T Thode, K Drenner, R Lewis, ... PLoS One 15 (7), e0235705, 2020 | 66 | 2020 |
Prostaglandin E2 induces miR675-5p to promote colorectal tumor metastasis via modulation of p53 expression B Cen, JD Lang, Y Du, J Wei, Y Xiong, N Bradley, D Wang, RN DuBois Gastroenterology 158 (4), 971-984. e10, 2020 | 63 | 2020 |
Methylation profiling defines an extensive field defect in histologically normal prostate tissues associated with prostate cancer B Yang, S Bhusari, J Kueck, P Weeratunga, J Wagner, G Leverson, ... Neoplasia 15 (4), 399-408, 2013 | 60 | 2013 |
Purification of cell subpopulations via immiscible filtration assisted by surface tension (IFAST) SM Berry, LN Strotman, JD Kueck, ET Alarid, DJ Beebe Biomedical microdevices 13, 1033-1042, 2011 | 60 | 2011 |
Local production of lactate, ribose phosphate, and amino acids by human triple-negative breast cancer JM Ghergurovich, JD Lang, MK Levin, N Briones, SJ Facista, C Mueller, ... Med 2 (6), 736-754. e6, 2021 | 55 | 2021 |
Improved methods for RNAseq-based alternative splicing analysis RF Halperin, A Hegde, JD Lang, EA Raupach, ... Scientific reports 11 (1), 10740, 2021 | 43 | 2021 |
The COX-2–PGE2 Pathway Promotes Tumor Evasion in Colorectal Adenomas J Wei, J Zhang, D Wang, B Cen, JD Lang, RN DuBois Cancer Prevention Research 15 (5), 285-296, 2022 | 39 | 2022 |
Hormonally responsive breast cancer cells in a microfluidic co-culture model as a sensor of microenvironmental activity JD Lang, SM Berry, GL Powers, DJ Beebe, ET Alarid Integrative Biology 5 (5), 807-816, 2013 | 38 | 2013 |
Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism KA Orlando, AK Douglas, A Abudu, Y Wang, B Tessier-Cloutier, W Su, ... Elife 9, e59073, 2020 | 31 | 2020 |
Streamlining gene expression analysis: integration of co-culture and mRNA purification SM Berry, C Singh, JD Lang, LN Strotman, ET Alarid, DJ Beebe Integrative Biology 6 (2), 224-231, 2014 | 21 | 2014 |
Identification of Driver Mutations in Rare Cancers: The Role of SMARCA4 in Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) JD Lang, WPD Hendricks Disease Gene Identification: Methods and Protocols, 367-379, 2018 | 15 | 2018 |
TP53 mutations and the association with platinum resistance in high grade serous ovarian carcinoma L Montemorano, ZB Shultz, A Farooque, M Hyun, RJ Chappell, ... Gynecologic Oncology 186, 26-34, 2024 | 3 | 2024 |
CD8+ cells and small viral reservoirs facilitate post-ART control of SIV replication in M3+ Mauritian cynomolgus macaques initiated on ART two weeks post-infection OE Harwood, LM Matschke, RV Moriarty, AJ Balgeman, AJ Weaver, ... PLoS Pathogens 19 (9), e1011676, 2023 | 3 | 2023 |
Novel functional insights revealed by distinct protein-protein interactions of the residual SWI/SNF complex in SMARCA4-deficient small cell carcinoma of the ovary … EA Raupach, K Garcia-Mansfield, R Sharma, AM Hegde, V David-Dirgo, ... bioRxiv, 794776, 2019 | 3 | 2019 |
Pilot clinical trial and phenotypic analysis in chemotherapy-pretreated, metastatic triple-negative breast cancer patients treated with oral TAK-228 and TAK-117 (PIKTOR) to … JD Lang, TVV Nguyen, MK Levin, PE Blas, HL Williams, ESR Rodriguez, ... Biomarker Research 11 (1), 73, 2023 | 2 | 2023 |