LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the toll adapters TRAM and TRIF KA Fitzgerald, DC Rowe, BJ Barnes, DR Caffrey, A Visintin, E Latz, ... The Journal of experimental medicine 198 (7), 1043-1055, 2003 | 1611 | 2003 |
Targeting potential drivers of COVID-19: Neutrophil extracellular traps BJ Barnes, JM Adrover, A Baxter-Stoltzfus, A Borczuk, J Cools-Lartigue, ... Journal of Experimental Medicine 217 (6), 2020 | 1579 | 2020 |
Neutrophil extracellular traps in COVID-19 Y Zuo, S Yalavarthi, H Shi, K Gockman, M Zuo, JA Madison, C Blair, ... JCI insight 5 (11), 2020 | 1548 | 2020 |
The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling A Schoenemeyer, BJ Barnes, ME Mancl, E Latz, N Goutagny, PM Pitha, ... Journal of Biological Chemistry 280 (17), 17005-17012, 2005 | 502 | 2005 |
Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon α genes BJ Barnes, PA Moore, PM Pitha Journal of Biological Chemistry 276 (26), 23382-23390, 2001 | 466 | 2001 |
Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells A Izaguirre, BJ Barnes, S Amrute, WS Yeow, N Megjugorac, J Dai, D Feng, ... Journal of Leucocyte Biology 74 (6), 1125-1138, 2003 | 442 | 2003 |
On the role of IRF in host defense B Barnes, B Lubyova, PM Pitha Journal of interferon & cytokine research 22 (1), 59-71, 2002 | 418 | 2002 |
Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes BJ Barnes, MJ Kellum, AE Field, PM Pitha Molecular and cellular biology, 2002 | 296 | 2002 |
Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection BJ Barnes, J Richards, M Mancl, S Hanash, L Beretta, PM Pitha Journal of Biological Chemistry 279 (43), 45194-45207, 2004 | 271 | 2004 |
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus … S Sigurdsson, HHH Göring, G Kristjansdottir, L Milani, G Nordmark, ... Human molecular genetics 17 (6), 872-881, 2008 | 227 | 2008 |
Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death BJ Barnes, MJ Kellum, KE Pinder, JA Frisancho, PM Pitha Cancer research 63 (19), 6424-6431, 2003 | 219 | 2003 |
Two discrete promoters regulate the alternatively spliced human interferon regulatory factor-5 isoforms: multiple isoforms with distinct cell type-specific expression … ME Mancl, G Hu, N Sangster-Guity, SL Olshalsky, K Hoops, ... Journal of Biological Chemistry 280 (22), 21078-21090, 2005 | 199 | 2005 |
Virus-induced Heterodimer Formation betweenIRF-5 and IRF-7 Modulates Assembly of theIFNA Enhanceosome in Vivo and Transcriptional Activity of IFNA Genes BJ Barnes, AE Field, PM Pitha-Rowe Journal of Biological Chemistry 278 (19), 16630-16641, 2003 | 168 | 2003 |
Neutrophil phenotypes and functions in cancer: A consensus statement DF Quail, B Amulic, M Aziz, BJ Barnes, E Eruslanov, ZG Fridlender, ... Journal of Experimental Medicine 219 (6), e20220011, 2022 | 163 | 2022 |
Signaling through IFN regulatory factor-5 sensitizes p53-deficient tumors to DNA Damage–Induced apoptosis and cell death G Hu, ME Mancl, BJ Barnes Cancer research 65 (16), 7403-7412, 2005 | 134 | 2005 |
Genetic variants and disease‐associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus D Feng, RC Stone, ML Eloranta, N Sangster‐Guity, G Nordmark, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2010 | 132 | 2010 |
IRF-5 is a mediator of the death receptor-induced apoptotic signaling pathway G Hu, BJ Barnes Journal of Biological Chemistry 284 (5), 2767-2777, 2009 | 108 | 2009 |
Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series AG Weber, AS Chau, M Egeblad, BJ Barnes, T Janowitz Molecular Medicine 26, 1-7, 2020 | 92 | 2020 |
Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression D Feng, N Sangster-Guity, R Stone, J Korczeniewska, ME Mancl, ... The Journal of Immunology 185 (10), 6003-6012, 2010 | 87 | 2010 |
Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes HM Akilesh, MB Buechler, JM Duggan, WO Hahn, B Matta, X Sun, ... Science 363 (6423), eaao5213, 2019 | 83 | 2019 |