Role for NLRP3 inflammasome–mediated, IL-1β–dependent responses in severe, steroid-resistant asthma RY Kim, JW Pinkerton, AT Essilfie, AAB Robertson, KJ Baines, AC Brown, ... American journal of respiratory and critical care medicine 196 (3), 283-297, 2017 | 379 | 2017 |
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis EL Beckett, RL Stevens, AG Jarnicki, RY Kim, I Hanish, NG Hansbro, ... Journal of Allergy and Clinical Immunology 131 (3), 752-762. e7, 2013 | 281 | 2013 |
Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease KL Bowerman, SF Rehman, A Vaughan, N Lachner, KF Budden, RY Kim, ... Nature communications 11 (1), 5886, 2020 | 253 | 2020 |
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase–mediated suppression of histone deacetylase 2 RY Kim, JC Horvat, JW Pinkerton, MR Starkey, AT Essilfie, JR Mayall, ... Journal of Allergy and Clinical Immunology 139 (2), 519-532, 2017 | 207 | 2017 |
Animal and translational models of SARS-CoV-2 infection and COVID-19 MD Johansen, A Irving, X Montagutelli, MD Tate, I Rudloff, MF Nold, ... Mucosal immunology 13 (6), 877-891, 2020 | 194 | 2020 |
Inflammasomes in the lung JW Pinkerton, RY Kim, AAB Robertson, JA Hirota, LG Wood, DA Knight, ... Molecular immunology 86, 44-55, 2017 | 178 | 2017 |
Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD) MS Eapen, PM Hansbro, K McAlinden, RY Kim, C Ward, TL Hackett, ... Scientific reports 7 (1), 13392, 2017 | 161 | 2017 |
Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma AT Essilfie, JC Horvat, RY Kim, JR Mayall, JW Pinkerton, EL Beckett, ... Thorax 70 (5), 458-467, 2015 | 143 | 2015 |
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages MC Runtsch, S Angiari, A Hooftman, R Wadhwa, Y Zhang, Y Zheng, ... Cell metabolism 34 (3), 487-501. e8, 2022 | 135 | 2022 |
Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma PM Hansbro, RY Kim, MR Starkey, C Donovan, K Dua, JR Mayall, G Liu, ... Immunological reviews 278 (1), 41-62, 2017 | 135 | 2017 |
MicroRNA profiling reveals a role for microRNA-218-5p in the pathogenesis of chronic obstructive pulmonary disease G Conickx, P Mestdagh, F Avila Cobos, FM Verhamme, T Maes, ... American journal of respiratory and critical care medicine 195 (1), 43-56, 2017 | 133 | 2017 |
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases G Liu, MA Cooley, AG Jarnicki, ACY Hsu, PM Nair, TJ Haw, M Fricker, ... JCI insight 1 (9), 2016 | 132 | 2016 |
Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction M Fricker, BJ Goggins, S Mateer, B Jones, RY Kim, SL Gellatly, ... JCI insight 3 (3), 2018 | 131 | 2018 |
Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology JC Horvat, MR Starkey, RY Kim, S Phipps, PG Gibson, KW Beagley, ... Journal of allergy and clinical immunology 125 (3), 617-625. e6, 2010 | 131 | 2010 |
Inflammasomes in COPD and neutrophilic asthma RY Kim, JW Pinkerton, PG Gibson, MA Cooper, JC Horvat, PM Hansbro Thorax 70 (12), 1199-1201, 2015 | 129 | 2015 |
Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease JC Horvat, MR Starkey, RY Kim, KW Beagley, JA Preston, PG Gibson, ... The Journal of Immunology 184 (8), 4159-4169, 2010 | 116 | 2010 |
Th2 cytokine antagonists: potential treatments for severe asthma PM Hansbro, GV Scott, AT Essilfie, RY Kim, MR Starkey, DH Nguyen, ... Expert Opinion on Investigational Drugs 22 (1), 49-69, 2013 | 102 | 2013 |
Role of iron in the pathogenesis of respiratory disease MK Ali, RY Kim, R Karim, JR Mayall, KL Martin, A Shahandeh, F Abbasian, ... The international journal of biochemistry & cell biology 88, 181-195, 2017 | 95 | 2017 |
Critical role for iron accumulation in the pathogenesis of fibrotic lung disease MK Ali, RY Kim, AC Brown, C Donovan, KS Vanka, JR Mayall, G Liu, ... The Journal of pathology 251 (1), 49-62, 2020 | 89 | 2020 |
A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease TJ Haw, MR Starkey, PM Nair, S Pavlidis, G Liu, DH Nguyen, AC Hsu, ... Mucosal immunology 9 (4), 859-872, 2016 | 81 | 2016 |