Chromatin position effects assayed by thousands of reporters integrated in parallel W Akhtar, J de Jong, AV Pindyurin, L Pagie, W Meuleman, J de Ridder, ... Cell 154 (4), 914-927, 2013 | 350 | 2013 |
Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model EA Bard-Chapeau, AT Nguyen, AG Rust, A Sayadi, P Lee, BQ Chua, ... Nature genetics 46 (1), 24-32, 2014 | 125 | 2014 |
Dosage-dependent tumor suppression by histone deacetylases 1 and 2 through regulation of c-Myc collaborating genes and p53 function MR Heideman, RH Wilting, E Yanover, A Velds, J de Jong, RM Kerkhoven, ... Blood, The Journal of the American Society of Hematology 121 (11), 2038-2050, 2013 | 101 | 2013 |
Chromatin landscapes of retroviral and transposon integration profiles J de Jong, W Akhtar, J Badhai, AG Rust, R Rad, J Hilkens, A Berns, ... PLoS genetics 10 (4), e1004250, 2014 | 100 | 2014 |
Prolonged Ezh2 depletion in glioblastoma causes a robust switch in cell fate resulting in tumor progression NA de Vries, D Hulsman, W Akhtar, J de Jong, DC Miles, M Blom, ... Cell reports 10 (3), 383-397, 2015 | 94 | 2015 |
Chemical profiling of the genome with anti-cancer drugs defines target specificities B Pang, J De Jong, X Qiao, LFA Wessels, J Neefjes Nature chemical biology 11 (7), 472-480, 2015 | 90 | 2015 |
A cell-based model of Nematostella vectensis gastrulation including bottle cell formation, invagination and zippering C Tamulonis, M Postma, HQ Marlow, CR Magie, J de Jong, J Kaandorp Developmental biology 351 (1), 217-228, 2011 | 71 | 2011 |
Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency S Gisler, JP Gonçalves, W Akhtar, J de Jong, AV Pindyurin, LFA Wessels, ... Nature communications 10 (1), 1598, 2019 | 64 | 2019 |
Towards realizing the vision of precision medicine: AI based prediction of clinical drug response J de Jong, I Cutcutache, M Page, S Elmoufti, C Dilley, H Fröhlich, ... Brain 144 (6), 1738-1750, 2021 | 61 | 2021 |
Deep learning for clustering of multivariate clinical patient trajectories with missing values J de Jong, MA Emon, P Wu, R Karki, M Sood, P Godard, A Ahmad, ... GigaScience 8 (11), giz134, 2019 | 58 | 2019 |
3D hotspots of recurrent retroviral insertions reveal long-range interactions with cancer genes S Babaei, W Akhtar, J De Jong, M Reinders, J De Ridder Nature communications 6 (1), 6381, 2015 | 41 | 2015 |
Using TRIP for genome-wide position effect analysis in cultured cells W Akhtar, AV Pindyurin, J De Jong, L Pagie, J Ten Hoeve, A Berns, ... Nature protocols 9 (6), 1255-1281, 2014 | 41 | 2014 |
Computational identification of insertional mutagenesis targets for cancer gene discovery J de Jong, J de Ridder, L van der Weyden, N Sun, M van Uitert, A Berns, ... Nucleic acids research 39 (15), e105-e105, 2011 | 38 | 2011 |
The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional … M van Keimpema, LJ Grüneberg, EJM Schilder-Tol, MECM Oud, ... Haematologica 102 (3), 573, 2017 | 22 | 2017 |
A computational approach towards a gene regulatory network for the developing Nematostella vectensis gut D Botman, E Röttinger, MQ Martindale, J de Jong, JA Kaandorp PLoS One 9 (7), e103341, 2014 | 18 | 2014 |
An explainable multimodal neural network architecture for predicting epilepsy comorbidities based on administrative claims data T Linden, J De Jong, C Lu, V Kiri, K Haeffs, H Fröhlich Frontiers in Artificial Intelligence 4, 610197, 2021 | 14 | 2021 |
Analysis of a spatial gene expression database for sea anemone Nematostella vectensis during early development D Botman, F Jansson, E Röttinger, MQ Martindale, J De Jong, ... BMC Systems Biology 9, 1-21, 2015 | 10 | 2015 |
Applications of DNA integrating elements: facing the bias bully J de Jong, LFA Wessels, M van Lohuizen, J de Ridder, W Akhtar Mobile Genetic Elements 4 (6), 1-6, 2014 | 7 | 2014 |
Predicting seizure recurrence after an initial seizure-like episode from routine clinical notes using large language models: a retrospective cohort study BK Beaulieu-Jones, MF Villamar, P Scordis, AP Bartmann, W Ali, ... The Lancet Digital Health 5 (12), e882-e894, 2023 | 6 | 2023 |
TRIP through the chromatin: a high throughput exploration of enhancer regulatory landscapes AV Pindyurin, J de Jong, W Akhtar Genomics 106 (3), 171-177, 2015 | 5 | 2015 |